Cryoballoon Versus Open Irrigated Radiofrequency Ablation in Patients With Paroxysmal Atrial Fibrillation: The Prospective, Randomized, Controlled, Noninferiority FreezeAF Study.

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Published in Circulation on August 17, 2015

Authors

Armin Luik1, Andrea Radzewitz2, Meinhard Kieser2, Marlene Walter2, Peter Bramlage2, Patrick Hörmann2, Kerstin Schmidt2, Nicolas Horn2, Maria Brinkmeier-Theofanopoulou2, Kevin Kunzmann2, Tobias Riexinger2, Gerhard Schymik2, Matthias Merkel2, Claus Schmitt2

Author Affiliations

1: From Medizinische Klinik IV, Städtisches Klinikum Karlsruhe, Academic Teaching Hospital of the University of Freiburg, Karlsruhe, Germany (A.L., A.R., M.W., P.H., K.S., N.H., M.B.-T., T.R., G.S., M.M., C.S.); Institute of Medical Biometry and Informatics, University of Heidelberg, Germany (M.K., K.K.); and Institute for Pharmacology and Preventive Medicine, Mahlow, Germany (P.B.). armin.luik@klinikum-karlsruhe.de.
2: From Medizinische Klinik IV, Städtisches Klinikum Karlsruhe, Academic Teaching Hospital of the University of Freiburg, Karlsruhe, Germany (A.L., A.R., M.W., P.H., K.S., N.H., M.B.-T., T.R., G.S., M.M., C.S.); Institute of Medical Biometry and Informatics, University of Heidelberg, Germany (M.K., K.K.); and Institute for Pharmacology and Preventive Medicine, Mahlow, Germany (P.B.).

Associated clinical trials:

FIRE AND ICE: Comparative Study of Two Ablation Procedures in Patients With Atrial Fibrillation | NCT01490814

PV-Isolation With the Cryoballoon Versus RF:a Randomized Controlled Prospective Non-inferiority Trial (FreezeAF) (FreezeAF) | NCT00774566

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