Published in Expert Opin Ther Targets on August 17, 2015
Mechanisms of Endothelial Dysfunction in Hypertensive Pregnancy and Preeclampsia. Adv Pharmacol (2016) 0.75
Decreased Homodimerization and Increased TIMP-1 Complexation of Uteroplacental and Uterine Arterial Matrix Metalloproteinase-9 during Hypertension-in-Pregnancy. Biochem Pharmacol (2017) 0.75
Increased Vascular and Uteroplacental Matrix Metalloproteinase-1 and -7 Levels and Collagen I Deposition in Hypertension-in-Pregnancy. Role of TNF. Am J Physiol Heart Circ Physiol (2017) 0.75
Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia. Prog Mol Biol Transl Sci (2017) 0.75
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest (2003) 13.72
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VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med (2008) 9.87
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med (2006) 7.06
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Paternal and maternal components of the predisposition to preeclampsia. N Engl J Med (2001) 4.02
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Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsia. Circ Res (2004) 2.52
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Genetic variants in pre-eclampsia: a meta-analysis. Hum Reprod Update (2013) 2.28
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Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature (2008) 2.09
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Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide. Hypertension (2001) 2.04
Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1. Hypertension (2009) 2.00
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of tumor necrosis factor-alpha. Hypertension (2005) 1.95
Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats. Hypertension (2005) 1.95
Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency. Blood (2008) 1.90
Circulating levels of immunoreactive cytokines in women with preeclampsia. Am J Reprod Immunol (1998) 1.83
Hypertension in response to chronic reductions in uterine perfusion in pregnant rats: effect of tumor necrosis factor-alpha blockade. Hypertension (2008) 1.78
Altered global gene expression in first trimester placentas of women destined to develop preeclampsia. Placenta (2008) 1.76
Maternal ethnicity, paternal ethnicity, and parental ethnic discordance: predictors of preeclampsia. Obstet Gynecol (2005) 1.60
The role of the immune system in preeclampsia. Mol Aspects Med (2007) 1.54
Primary, secondary, and tertiary prevention of pre-eclampsia. Lancet (2001) 1.51
The glomerular injury of preeclampsia. J Am Soc Nephrol (2007) 1.50
Circulating concentrations of sFlt1 (soluble fms-like tyrosine kinase 1) in fetal and maternal serum during pre-eclampsia. Eur J Obstet Gynecol Reprod Biol (2005) 1.48
Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2. Endocrinology (2008) 1.47
Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expression. Hypertension (2008) 1.45
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretion. Am J Hypertens (2005) 1.40
Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat. Hypertension (2000) 1.37
CD4+ T-helper cells stimulated in response to placental ischemia mediate hypertension during pregnancy. Hypertension (2011) 1.32
Effective prediction of preeclampsia by a combined ratio of angiogenesis-related factors. Obstet Gynecol (2008) 1.26
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats. Hypertension (2002) 1.24
Tumor necrosis factor-alpha-induced hypertension in pregnant rats results in decreased renal neuronal nitric oxide synthase expression. Am J Hypertens (2002) 1.23
Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin-1, and angiopoietin-2. J Clin Endocrinol Metab (2002) 1.21
Activation of leukocytes during the uteroplacental passage in preeclampsia. Hypertension (2002) 1.17
Twin pregnancy and the risk of preeclampsia: bigger placenta or relative ischemia? Am J Obstet Gynecol (2008) 1.17
Microalbuminuria after pregnancy complicated by pre-eclampsia. Nephrol Dial Transplant (1999) 1.16
Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats. Hypertension (1998) 1.16
Human-specific expression of Siglec-6 in the placenta. Glycobiology (2007) 1.15
Uterine vascular function in a transgenic preeclampsia rat model. Hypertension (2008) 1.12
First-trimester serum levels of soluble endoglin and soluble fms-like tyrosine kinase-1 as first-trimester markers for late-onset preeclampsia. Am J Obstet Gynecol (2008) 1.12
The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy. Endocrinology (2009) 1.08
Abnormal placentation and the syndrome of preeclampsia. Semin Nephrol (2004) 1.06
Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia condition. Placenta (2005) 1.03
Mesangial AT1/B2 receptor heterodimers contribute to angiotensin II hyperresponsiveness in experimental hypertension. J Mol Neurosci (2005) 1.01
Intolerance to volume expansion: a theorized mechanism for the development of preeclampsia. Obstet Gynecol (1998) 1.01
Uric acid attenuates trophoblast invasion and integration into endothelial cell monolayers. Am J Physiol Cell Physiol (2009) 1.00
Enhanced expression of Ang-(1-7) during pregnancy. Braz J Med Biol Res (2004) 1.00
Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant rats. Am J Physiol Regul Integr Comp Physiol (2002) 0.99
Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy. J Clin Lab Anal (2009) 0.99
Preeclampsia-like symptoms induced in mice by fetoplacental expression of STOX1 are reversed by aspirin treatment. Hypertension (2013) 0.98
Nitric oxide production with preeclampsia. Obstet Gynecol (1999) 0.98
Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn. Pharmacol Rev (2012) 0.97
Vascular matrix metalloproteinase-9 mediates the inhibition of myogenic reactivity in small arteries isolated from rats after short-term administration of relaxin. Endocrinology (2006) 0.97
Levels of antibodies against cytomegalovirus and Chlamydophila pneumoniae are increased in early onset pre-eclampsia. BJOG (2003) 0.97
Hepatoprotective and anti-inflammatory effects of silibinin on experimental preeclampsia induced by L-NAME in rats. Life Sci (2012) 0.96
Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies. Placenta (2007) 0.96
Circulating angiogenic factors in singleton vs multiple-gestation pregnancies. Am J Obstet Gynecol (2008) 0.96
Pregnancy-associated reduction in vascular protein kinase C activity rebounds during inhibition of NO synthesis. Am J Physiol Regul Integr Comp Physiol (2000) 0.94
Systemic hemodynamics and regional blood flow during chronic nitric oxide synthesis inhibition in pregnant rats. Hypertension (1998) 0.94
Generation of reactive oxygen species by neutrophils and endothelial cell injury in normal and preeclamptic pregnancies. Hypertension (2005) 0.93
STOX1 overexpression in choriocarcinoma cells mimics transcriptional alterations observed in preeclamptic placentas. PLoS One (2008) 0.92
Is preeclampsia an infectious disease? Acta Obstet Gynecol Scand (2001) 0.91
Neutrophil activation induced by placental factors in normal and pre-eclamptic pregnancies in vitro. Placenta (2001) 0.91
Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites. Am J Physiol Regul Integr Comp Physiol (2007) 0.90
STOX2 but not STOX1 is differentially expressed in decidua from pre-eclamptic women: data from the Second Nord-Trondelag Health Study. Mol Hum Reprod (2010) 0.90
Tumor necrosis factor-alpha in the placenta is not elevated in pre-eclamptic patients despite its elevation in peripheral blood. Am J Reprod Immunol (2005) 0.90
Downregulation of microvascular endothelial type B endothelin receptor is a central vascular mechanism in hypertensive pregnancy. Hypertension (2014) 0.90
Adhesion molecules changes at 20 gestation weeks in pregnancies complicated by preeclampsia. Eur J Obstet Gynecol Reprod Biol (2007) 0.89
Cellular mRNA expressions of anti-oxidant factors in the blood of preeclamptic women. Prenat Diagn (2009) 0.88
Association of -634G/C and 936C/T polymorphisms of the vascular endothelial growth factor with spontaneous preterm delivery. Acta Obstet Gynecol Scand (2004) 0.87
Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins. Placenta (2008) 0.87
STOX1: Key player in trophoblast dysfunction underlying early onset preeclampsia with growth retardation. J Pregnancy (2010) 0.87
Expression of endothelial nitric oxide synthase by extravillous trophoblast cells in the human placenta. Placenta (2000) 0.87
Risk factors and mediators of the vascular dysfunction associated with hypertension in pregnancy. Cardiovasc Hematol Disord Drug Targets (2010) 0.87
Fine mapping and SNP analysis of positional candidates at the preeclampsia susceptibility locus (PREG1) on chromosome 2. Hum Biol (2004) 0.87
Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6-infused pregnant rats. Hypertension (2004) 0.86
Prediction of preeclampsia by analysis of cell-free messenger RNA in maternal plasma. Am J Obstet Gynecol (2009) 0.86
Pregnancy outcome and fibrinolytic, endothelial and coagulation markers in women undergoing uterine artery Doppler screening at 23 weeks. J Thromb Haemost (2009) 0.86
Enhanced [Ca2+]i in renal arterial smooth muscle cells of pregnant rats with reduced uterine perfusion pressure. Am J Physiol Heart Circ Physiol (2002) 0.85
Altered matrix metalloproteinase-2 and -9 expression/activity links placental ischemia and anti-angiogenic sFlt-1 to uteroplacental and vascular remodeling and collagen deposition in hypertensive pregnancy. Biochem Pharmacol (2014) 0.83
GRP78 as a marker of pre-eclampsia: an exploratory study. Mol Hum Reprod (2009) 0.83
Possible gene-gene interaction of KIR2DL4 with its cognate ligand HLA-G in modulating risk for preeclampsia. Reprod Sci (2009) 0.82
Soluble fms-like tyrosine kinase 1. N Engl J Med (2004) 0.82
Differential [Ca2+]i signaling of vasoconstriction in mesenteric microvessels of normal and reduced uterine perfusion pregnant rats. Am J Physiol Regul Integr Comp Physiol (2008) 0.82
Plasma level of soluble c-Met is tightly associated with the clinical risk of preeclampsia. Am J Obstet Gynecol (2009) 0.82
Interleukin 10 gene promoter polymorphisms in women with early-onset pre-eclampsia. Clin Exp Immunol (2014) 0.81
[Ca(2+)](i) signaling in renal arterial smooth muscle cells of pregnant rat is enhanced during inhibition of NOS. Am J Physiol Regul Integr Comp Physiol (2001) 0.81
Angiotensinogen genotype and plasma volume in nulligravid women. Obstet Gynecol (1998) 0.81
Serum levels of interleukin-6, interleukin-1beta and human chorionic gonadotropin in pre-eclamptic and normal pregnancy. Gynecol Endocrinol (2007) 0.81
Association between 894G>T endothelial nitric oxide synthase gene polymorphisms and metabolic syndrome. Arq Bras Endocrinol Metabol (2008) 0.80
Polymorphisms of FAS and FAS ligand genes in preeclamptic women. Eur J Obstet Gynecol Reprod Biol (2009) 0.80
Maternal serum and amniotic fluid inhibin A levels in women who subsequently develop severe preeclampsia. J Korean Med Sci (2006) 0.79
Renal angiotensin-II receptors expression changes in a model of preeclampsia. Hypertens Pregnancy (2007) 0.79
Vascular contraction and preeclampsia: downregulation of the Angiotensin receptor 1 by hemopexin in vitro. Hypertension (2009) 0.79
Angiogenin and vascular endothelial growth factor in pregnancies complicated by preeclampsia. Int J Gynaecol Obstet (2004) 0.78