Reduced rate of copy number aberrations in mucinous colorectal carcinoma.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 26329972)

Published in Oncotarget on September 22, 2015

Authors

Niek Hugen1, Femke Simmer2, Leonie J M Mekenkamp3, Miriam Koopman4, Evert van den Broek5, Johannes H W de Wilt1, Cornelis J A Punt6, Bauke Ylstra5, Gerrit A Meijer5, Iris D Nagtegaal2

Author Affiliations

1: Department of Surgery, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
2: Department of Pathology, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
3: Department of Internal Medicine, Medical Spectrum Twente Enschede, 7500 KA Enschede, The Netherlands.
4: Department of Medical Oncology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
5: Department of Pathology, VU University Medical Centre, 1007 MB Amsterdam, The Netherlands.
6: Department of Medical Oncology, Academic Medical Center University of Amsterdam, 1100 DD Amsterdam, The Netherlands.

Associated clinical trials:

Cetuximab, Capecitabine, Oxaliplatin and Bevacizumab in Advanced Colorectal Cancer | NCT00208546

Sequential Versus Combination Chemotherapy in Advanced Colorectal Carcinoma | NCT00312000

Articles cited by this

BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics (2010) 53.23

Comprehensive molecular characterization of human colon and rectal cancer. Nature (2012) 34.13

Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics (2004) 24.18

Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med (2009) 11.63

On the road to cancer: aneuploidy and the mitotic checkpoint. Nat Rev Cancer (2005) 7.53

Microsatellite instability in colorectal cancer. Gastroenterology (2010) 7.39

Does aneuploidy cause cancer? Curr Opin Cell Biol (2006) 3.89

Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial. Lancet (2007) 3.85

The significance of unstable chromosomes in colorectal cancer. Nat Rev Cancer (2003) 3.21

Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis. Gut (2008) 2.68

Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas. Cancer Res (2004) 2.56

High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridization. Carcinogenesis (2004) 2.13

Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability. Gastroenterology (2002) 1.91

Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells. Nat Cell Biol (2014) 1.86

Clinicopathology and outcomes for mucinous and signet ring colorectal adenocarcinoma: analysis from the National Cancer Data Base. Ann Surg Oncol (2012) 1.82

Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression. Gut (2008) 1.77

Deficient mismatch repair system in patients with sporadic advanced colorectal cancer. Br J Cancer (2009) 1.75

Mucinous adenocarcinomas: poor prognosis in metastatic colorectal cancer. Eur J Cancer (2012) 1.73

The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes. Genes Chromosomes Cancer (2006) 1.67

Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation. J Clin Pathol (1998) 1.54

CGHregions: dimension reduction for array CGH data with minimal information loss. Cancer Inform (2007) 1.49

Mucinous histology predicts for poor response rate and overall survival of patients with colorectal cancer and treated with first-line oxaliplatin- and/or irinotecan-based chemotherapy. Br J Cancer (2009) 1.48

Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features. Mod Pathol (2013) 1.47

BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer. Int J Cancer (2006) 1.46

Smoothing waves in array CGH tumor profiles. Bioinformatics (2009) 1.45

Mucinous histology predicts for reduced fluorouracil responsiveness and survival in advanced colorectal cancer. Ann Oncol (2005) 1.41

Metastatic pattern in colorectal cancer is strongly influenced by histological subtype. Ann Oncol (2014) 1.39

Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN, and FOCUS studies. Clin Cancer Res (2014) 1.33

Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour DNA ploidy, genotypes and phenotypes. Br J Cancer (1999) 1.28

Across array comparative genomic hybridization: a strategy to reduce reference channel hybridizations. Genes Chromosomes Cancer (2008) 1.25

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer. Clin Cancer Res (2013) 1.17

TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression. Gut (2011) 1.15

PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival. PLoS One (2013) 1.13

Amplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancer. PLoS One (2011) 1.03

Gain of chromosome 20q is an indicator of poor prognosis in colorectal cancer. Cell Oncol (2007) 0.99

Prognosis and value of adjuvant chemotherapy in stage III mucinous colorectal carcinoma. Ann Oncol (2013) 0.95

Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer. J Pathol (2000) 0.93

Mucinous carcinomas of the colorectum have distinct molecular genetic characteristics. Int J Oncol (2005) 0.91

Identification of chromosomal aberrations of metastatic potential in colorectal carcinoma. Genes Chromosomes Cancer (2010) 0.90

Genomic landscape of metastatic colorectal cancer. Nat Commun (2014) 0.89

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases. BMC Cancer (2010) 0.89

Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas. Genome Biol (2014) 0.89

Mucinous carcinomas of the colon and rectum show higher rates of microsatellite instability and lower rates of chromosomal instability: a study matched for T classification and tumor location. Cancer (2005) 0.86

CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression. Cell Oncol (Dordr) (2012) 0.86

Mucinous histology of colon cancer predicts poor outcomes with FOLFOX regimen in metastatic colon cancer. J Chemother (2012) 0.85

Evidence for various 20q status using allelotyping, CGH arrays, and quantitative PCR in distal CIN colon cancers. Cancer Lett (2009) 0.78