Influence of ejection fraction on outcomes and efficacy of spironolactone in patients with heart failure with preserved ejection fraction.

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Published in Eur Heart J on September 15, 2015

Authors

Scott D Solomon1, Brian Claggett2, Eldrin F Lewis2, Akshay Desai2, Inder Anand3, Nancy K Sweitzer4, Eileen O'Meara5, Sanjiv J Shah6, Sonja McKinlay7, Jerome L Fleg8, George Sopko8, Bertram Pitt9, Marc A Pfeffer2, TOPCAT Investigators

Author Affiliations

1: Cardiovascular Division, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115, USA ssolomon@rics.bwh.harvard.edu.
2: Cardiovascular Division, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115, USA.
3: Minneapolis VA Hospital, Minneapolis, MN, USA.
4: University of Arizona, Tuscon, AZ, USA.
5: Montreal Heart Institute, Montreal, Canada.
6: Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
7: New England Research Institute, Watertown, MA, USA.
8: National Heart, Lung and Blood Institute, Bethesda, MD, USA.
9: University of Michigan, Ann Arbor, MI, USA.

Associated clinical trials:

Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic Function (TOPCAT) | NCT00094302

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