PubRank

Fengling Li

Author PubWeight™ 38.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1. ACS Chem Biol 2013 1.89
2 Altered macrophage function contributes to colitis in mice defective in the phosphoinositide-3 kinase subunit p110δ. Gastroenterology 2010 1.80
3 Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun 2012 1.67
4 Activation of the murine interleukin-12 p40 promoter by functional interactions between NFAT and ICSBP. J Biol Chem 2003 1.56
5 Inhibition of interleukin-12 p40 transcription and NF-kappaB activation by nitric oxide in murine macrophages and dendritic cells. J Biol Chem 2003 1.49
6 Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis. J Leukoc Biol 2009 1.45
7 An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis. J Immunol 2011 1.31
8 Functional characterization of the Arabidopsis beta-ketoacyl-coenzyme A reductase candidates of the fatty acid elongase. Plant Physiol 2009 1.28
9 Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis. J Immunol 2010 1.23
10 Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP. J Med Chem 2013 1.23
11 Amelioration of chronic murine colitis by peptide-mediated transduction of the IkappaB kinase inhibitor NEMO binding domain peptide. J Immunol 2007 1.22
12 Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids. Plant Physiol 2010 1.19
13 Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2. J Am Chem Soc 2012 1.17
14 Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. Biochem J 2013 1.12
15 Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation. Gastroenterology 2002 1.06
16 Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8. J Med Chem 2014 1.05
17 Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J Med Chem 2013 1.00
18 Nahuoic acid A produced by a Streptomyces sp. isolated from a marine sediment is a selective SAM-competitive inhibitor of the histone methyltransferase SETD8. Org Lett 2012 0.97
19 Insertional mutant analysis reveals that long-chain acyl-CoA synthetase 1 (LACS1), but not LACS8, functionally overlaps with LACS9 in Arabidopsis seed oil biosynthesis. Plant J 2010 0.92
20 A cell permeable peptide inhibitor of NFAT inhibits macrophage cytokine expression and ameliorates experimental colitis. PLoS One 2012 0.92
21 Kininogen deficiency modulates chronic intestinal inflammation in genetically susceptible rats. Am J Physiol Gastrointest Liver Physiol 2002 0.88
22 Development of a Brassica seed cDNA microarray. Genome 2008 0.87
23 A chemical tool for in vitro and in vivo precipitation of lysine methyltransferase G9a. ChemMedChem 2014 0.86
24 An efficient method for producing an indexed, insertional-mutant library in rice. Genomics 2007 0.86
25 A new and reliable animal model for optic nerve injury. Curr Eye Res 2012 0.86
26 A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3). Angew Chem Int Ed Engl 2015 0.85
27 The mutation Ser511Asn leads to N-glycosylation and increases the cleavage of high molecular weight kininogen in rats genetically susceptible to inflammation. Blood 2003 0.83
28 Perilla oil and exercise decrease expressions of tumor necrosis factor-alpha, plasminogen activator inhibitor-1 and highly sensitive C-reactive protein in patients with hyperlipidemia. J Tradit Chin Med 2013 0.81
29 Strategy to target the substrate binding site of SET domain protein methyltransferases. J Chem Inf Model 2013 0.81
30 Qiguiyishen decoction reduced the accumulation of extracellular matrix in the kidneys of rats with adriamycin-induced nephropathy. J Tradit Chin Med 2014 0.79
31 Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia. Nat Chem Biol 2015 0.78
32 Chronic intestinal inflammation and angiogenesis in genetically susceptible rats is modulated by kininogen deficiency. Int Immunopharmacol 2002 0.77
33 In vitro and in vivo evaluation of a water-in-oil microemulsion system for enhanced peptide intestinal delivery. AAPS J 2012 0.77
34 Clinical application of iodine-eluting stent in patients with advanced esophageal cancer. Oncol Lett 2013 0.76
35 Aβ(1-42) disrupts the expression and function of KLF2 in Alzheimer's disease mediated by p53. Biochem Biophys Res Commun 2013 0.76
36 Erratum: The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol 2017 0.75