Published in Genomics Proteomics Bioinformatics on September 16, 2015
Autoimmune Diseases in the Bioinformatics Paradigm. Genomics Proteomics Bioinformatics (2015) 0.75
The Sequence Alignment/Map format and SAMtools. Bioinformatics (2009) 232.39
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
Global cancer statistics. CA Cancer J Clin (2011) 185.92
A method and server for predicting damaging missense mutations. Nat Methods (2010) 78.53
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res (2008) 54.83
Global cancer statistics, 2012. CA Cancer J Clin (2015) 53.52
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature (2005) 18.30
Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell (2011) 16.72
Esophageal cancer. N Engl J Med (2003) 15.23
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature (2005) 14.65
The genomic complexity of primary human prostate cancer. Nature (2011) 14.06
Cell cycle checkpoints: preventing an identity crisis. Science (1996) 13.74
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature (2011) 13.30
ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med (2010) 13.07
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell (2006) 12.72
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature (2006) 11.76
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature (2006) 11.18
Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science (2010) 10.78
GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol (2011) 9.60
Genomic instability--an evolving hallmark of cancer. Nat Rev Mol Cell Biol (2010) 7.11
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell (1992) 7.06
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet (2012) 6.65
EUROCARE-3: survival of cancer patients diagnosed 1990-94--results and commentary. Ann Oncol (2003) 5.78
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Nat Genet (2012) 4.82
Expression of Yes-associated protein in common solid tumors. Hum Pathol (2008) 4.61
Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation. Cancer Cell (2006) 4.10
Identification of genomic alterations in oesophageal squamous cell cancer. Nature (2014) 3.10
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes. Nat Genet (2012) 2.71
Pattern of recurrence following complete resection of esophageal carcinoma and factors predictive of recurrent disease. Cancer (2003) 2.23
Genomic and molecular characterization of esophageal squamous cell carcinoma. Nat Genet (2014) 2.02
The genetics of cell cycle checkpoints. Curr Opin Genet Dev (1995) 1.92
Genetic landscape of esophageal squamous cell carcinoma. Nat Genet (2014) 1.89
Wnt/β-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells. J Biol Chem (2012) 1.89
Risk factors for oesophageal cancer in northeast China. Int J Cancer (1994) 1.73
The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability. Proc Natl Acad Sci U S A (2003) 1.69
The CDKN2A (p16) gene and human cancer. Mol Med (1997) 1.46
Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma. BMC Genomics (2010) 1.40
R-Gada: a fast and flexible pipeline for copy number analysis in association studies. BMC Bioinformatics (2010) 1.29
Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma. Am J Hum Genet (2015) 1.28
Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis. PLoS One (2012) 1.26
CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome. Breast Cancer Res Treat (2007) 1.22
Genomic characterization of esophageal squamous cell carcinoma from a high-risk population in China. Cancer Res (2009) 1.20
Tumor suppressors, chromosomal instability, and hepatitis C virus-associated liver cancer. Annu Rev Pathol (2009) 1.20
Prognostic factors and family history for survival of esophageal squamous cell carcinoma patients after surgery. Ann Thorac Surg (2010) 1.13
Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array. BMC Genomics (2006) 1.09
p53 abnormalities and genomic instability in primary human breast carcinomas. Cancer Res (1995) 1.09
Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32). Blood (2000) 1.09
p53 Mutation status predicts pathological response to chemoradiotherapy in locally advanced esophageal cancer. Ann Surg Oncol (2009) 1.06
p53: the attractive tumor suppressor in the cancer research field. J Biomed Biotechnol (2010) 1.02
Comparative genomic hybridization analysis of genetic aberrations associated with development of esophageal squamous cell carcinoma in Henan, China. World J Gastroenterol (2008) 0.95
The function of ORAOV1/LTO1, a gene that is overexpressed frequently in cancer: essential roles in the function and biogenesis of the ribosome. Oncogene (2013) 0.92
Characterization of genetic alteration patterns in human esophageal squamous cell carcinoma using selected microsatellite markers spanning multiple loci. Int J Oncol (2007) 0.91
TP53 gene mutation profile in esophageal squamous cell carcinomas. Cancer Res (1993) 0.91
Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays. Lab Invest (2008) 0.88
Characterization of gene rearrangements resulted from genomic structural aberrations in human esophageal squamous cell carcinoma KYSE150 cells. Gene (2012) 0.88
Chromosomal comparative genomic hybridization abnormalities in early- and late-onset human breast cancers: correlation with disease progression and TP53 mutations. Cancer Genet Cytogenet (2004) 0.87
Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study. Breast Cancer Res Treat (2010) 0.81
Genome interrupted: sequencing of prostate cancer reveals the importance of chromosomal rearrangements. Genome Med (2011) 0.80
Overexpression of cortactin in head and neck squamous cell carcinomas can be uncoupled from augmented EGF receptor expression. Acta Oncol (2008) 0.78
p53 gene mutation in 150 dissected lymph nodes in a patient with esophageal cancer. Dis Esophagus (1998) 0.76
[Significance of p53 gene mutation and P53 protein expression abnormality on the prognosis of esophageal cancer: a meta-analysis study]. Zhonghua Liu Xing Bing Xue Za Zhi (2004) 0.76
In vitro transcriptome analysis of two Chinese isolates of Streptococcus suis serotype 2. Genomics Proteomics Bioinformatics (2014) 0.75
Identification of cancer patients using claims data from health insurance systems: A real-world comparative study. Chin J Cancer Res (2019) 0.75
Incidence and clearance of oral human papillomavirus infection: A population-based cohort study in rural China. Oncotarget (2017) 0.75