Published in Oncotarget on October 06, 2015
Why Doesn't Primary Biliary Cholangitis Respond to Immunosuppressive Medications? Curr Hepatol Rep (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Primary biliary cirrhosis. N Engl J Med (2005) 7.59
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med (2009) 6.80
The PD-1 pathway in tolerance and autoimmunity. Immunol Rev (2010) 5.99
B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes. Immunity (2004) 4.60
Role of LAG-3 in regulatory T cells. Immunity (2004) 4.36
CD4+ Tregs and immune control. J Clin Invest (2004) 2.85
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity (2011) 2.49
Ae2a,b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis. Gastroenterology (2008) 1.87
MicroRNA-513 regulates B7-H1 translation and is involved in IFN-gamma-induced B7-H1 expression in cholangiocytes. J Immunol (2009) 1.76
The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis. Gastroenterology (2005) 1.67
Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis. J Clin Invest (2002) 1.65
Primary biliary cirrhosis: a 2010 update. J Hepatol (2010) 1.57
Development and characterization of polarized primary cultures of rat intrahepatic bile duct epithelial cells. Lab Invest (1996) 1.56
Apotopes and the biliary specificity of primary biliary cirrhosis. Hepatology (2009) 1.55
Liver-targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis. Hepatology (2006) 1.53
Molecular physiology and genetics of Na+-independent SLC4 anion exchangers. J Exp Biol (2009) 1.50
Primary biliary cirrhosis. Semin Immunopathol (2009) 1.46
Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis. J Clin Invest (2001) 1.40
Up-regulation of microRNA 506 leads to decreased Cl-/HCO3- anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis. Hepatology (2012) 1.38
Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. Hepatology (2013) 1.33
Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity. Proc Natl Acad Sci U S A (2010) 1.23
Liver antigen-presenting cells. J Hepatol (2010) 1.22
The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies. Hepatology (2010) 1.16
Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells. J Immunol (2013) 1.14
Isolation of small polarized bile duct units. Proc Natl Acad Sci U S A (1995) 1.14
Anion exchanger 2 is essential for spermiogenesis in mice. Proc Natl Acad Sci U S A (2003) 1.11
New insights to the immunopathology and autoimmune responses in primary biliary cirrhosis. Cell Immunol (2006) 1.11
A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes. Hepatology (2012) 1.11
Shotgun proteomics: identification of unique protein profiles of apoptotic bodies from biliary epithelial cells. Hepatology (2014) 1.06
Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells. J Autoimmun (2014) 1.02
Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFβRII mice. Hepatology (2013) 0.98
Assessment of biliary bicarbonate secretion in humans by positron emission tomography. Gastroenterology (1999) 0.96
Modified culture conditions enhance expression of differentiated phenotypic properties of normal rat cholangiocytes. Lab Invest (2000) 0.96
Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis. Hepatology (2011) 0.94
CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease. J Immunol (2010) 0.93
Naturally-occurring regulatory T cells are increased in inflamed portal tracts with cholangiopathy in primary biliary cirrhosis. J Clin Pathol (2006) 0.89
Murine models of autoimmune cholangitis. Curr Opin Gastroenterol (2010) 0.88
Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosis. Hepatology (2011) 0.87
Bicarbonate secretion of mouse cholangiocytes involves Na(+)-HCO(3)(-) cotransport in addition to Na(+)-independent Cl(-)/HCO(3)(-) exchange. Hepatology (2010) 0.87
Approaches to the pathogenesis of primary biliary cirrhosis through animal models. Clin Res Hepatol Gastroenterol (2011) 0.83
Role of the anion exchanger 2 in the pathogenesis and treatment of primary biliary cirrhosis. Dig Dis (2011) 0.81
Role of AE2 for pHi regulation in biliary epithelial cells. Front Physiol (2014) 0.80
Etiopathogenesis of primary biliary cirrhosis: an overview of recent developments. Hepatol Int (2012) 0.78
Anion exchanger 2 is critical for CD8(+) T cells to maintain pHi homeostasis and modulate immune responses. Eur J Immunol (2014) 0.78
Mouse models of primary biliary cirrhosis. Curr Pharm Des (2015) 0.77
The lipid flippase heterodimer ATP8B1-CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells. Biochim Biophys Acta (2014) 0.79
The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator. Biochim Biophys Acta (2016) 0.76
Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis. Lab Invest (2014) 0.75
ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes. Hepatology (2016) 0.75