Published in Spermatogenesis on January 26, 2015
Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility. J Clin Invest (2017) 0.84
Transplanted human p75-positive stem Leydig cells replace disrupted Leydig cells for testosterone production. Cell Death Dis (2017) 0.75
The role of vitamin D in male fertility: A focus on the testis. Rev Endocr Metab Disord (2017) 0.75
Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. Nat Genet (1997) 3.69
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. Proc Natl Acad Sci U S A (2004) 3.48
Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues. Proc Natl Acad Sci U S A (2002) 3.08
A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty. Nature (1993) 2.68
Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance. Proc Natl Acad Sci U S A (1998) 2.50
Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells. Proc Natl Acad Sci U S A (2004) 2.41
Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice. Mol Endocrinol (2001) 1.86
Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor. N Engl J Med (1999) 1.83
Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues. J Histochem Cytochem (1993) 1.77
Hormonal regulation of spermatogenesis in primates and man: insights for development of the male hormonal contraceptive. J Androl (2002) 1.76
Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens. Endocrinology (1994) 1.75
Targeted disruption of luteinizing hormone beta-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility. Proc Natl Acad Sci U S A (2004) 1.73
Localization of androgen and estrogen receptors in adult male mouse reproductive tract. J Androl (2002) 1.69
Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone. N Engl J Med (1992) 1.69
Androgen action via testicular peritubular myoid cells is essential for male fertility. FASEB J (2009) 1.64
The functional significance of FSH in spermatogenesis and the control of its secretion in male primates. Endocr Rev (2001) 1.61
Localization of oestrogen receptor alpha, oestrogen receptor beta and androgen receptors in the rat reproductive organs. J Endocrinol (2000) 1.57
Identification of specific sites of hormonal regulation in spermatogenesis in rats, monkeys, and man. Recent Prog Horm Res (2002) 1.55
Androgen receptor roles in spermatogenesis and fertility: lessons from testicular cell-specific androgen receptor knockout mice. Endocr Rev (2009) 1.55
Induction of spermatogenesis by androgens in gonadotropin-deficient (hpg) mice. Endocrinology (1995) 1.47
The regulation of spermatogenesis by androgens. Semin Cell Dev Biol (2014) 1.47
The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction. Endocrinology (2000) 1.43
Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse. Endocrinology (2003) 1.42
Maintenance of advanced spermatogenic cells in the adult rat testis: quantitative relationship to testosterone concentration within the testis. Endocrinology (1989) 1.40
Advances in male contraception. Endocr Rev (2008) 1.39
Murine germ cells do not require functional androgen receptors to complete spermatogenesis following spermatogonial stem cell transplantation. Endocrinology (2001) 1.33
Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility. Nat Genet (1997) 1.30
Luteinizing hormone beta mutation and hypogonadism in men and women. N Engl J Med (2007) 1.29
Hormonal regulation of spermatogenesis. Int J Androl (2004) 1.24
An update of the pathophysiology of human gonadotrophin subunit and receptor gene mutations and polymorphisms. Reproduction (2005) 1.23
Androgen receptor distribution in rat testis: new implications for androgen regulation of spermatogenesis. Endocrinology (1994) 1.21
Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells. Proc Natl Acad Sci U S A (2006) 1.21
Hormonal regulation of male germ cell development. J Endocrinol (2010) 1.20
Infertility with defective spermatogenesis and steroidogenesis in male mice lacking androgen receptor in Leydig cells. Endocrine (2007) 1.18
Hormonal regulation of spermatogenesis and spermiogenesis. J Steroid Biochem Mol Biol (2008) 1.17
Androgens and spermatogenesis: lessons from transgenic mouse models. Philos Trans R Soc Lond B Biol Sci (2010) 1.16
The differential secretion of FSH and LH: regulation through genes, feedback and packaging. Reprod Suppl (2003) 1.16
Non-classical actions of testosterone and spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 1.09
Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice. Mol Cell Endocrinol (2008) 1.08
Postnatal and pubertal development of the rhesus monkey (Macaca mulatta) testis. Ann N Y Acad Sci (2005) 1.08
Male hypogonadism due to a mutation in the gene for the beta-subunit of follicle-stimulating hormone. N Engl J Med (1998) 1.06
Spermatogenesis and sertoli cell activity in mice lacking sertoli cell receptors for follicle-stimulating hormone and androgen. Endocrinology (2008) 1.05
The androgen microenvironment of the human testis and hormonal control of spermatogenesis. Ann N Y Acad Sci (2005) 1.04
Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models. Hum Reprod Update (2010) 1.04
Sertoli and germ cell development in hypogonadal (hpg) mice expressing transgenic follicle-stimulating hormone alone or in combination with testosterone. Endocrinology (2003) 1.04
Testosterone signaling and the regulation of spermatogenesis. Spermatogenesis (2011) 1.04
Spermatogenesis without gonadotropins: maintenance has a lower testosterone threshold than initiation. Endocrinology (1999) 1.03
Male hypogonadism caused by homozygous deletion of exon 10 of the luteinizing hormone (LH) receptor: differential action of human chorionic gonadotropin and LH. J Clin Endocrinol Metab (2000) 1.03
Development and function of the adult generation of Leydig cells in mice with Sertoli cell-selective or total ablation of the androgen receptor. Endocrinology (2005) 1.03
Maintenance of spermatogenesis in hypogonadotropic hypogonadal men with human chorionic gonadotropin alone. Eur J Endocrinol (2002) 1.02
The consequences of actin disruption at Sertoli ectoplasmic specialization sites facing spermatids after in vivo exposure of rat testis to cytochalasin D. Biol Reprod (1988) 1.02
The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis. Proc Natl Acad Sci U S A (2003) 1.01
What have we learned about gonadotropin function from gonadotropin subunit and receptor knockout mice? Reproduction (2005) 1.00
Testosterone replacement therapy induces spermatogenesis and partially restores fertility in luteinizing hormone receptor knockout mice. Endocrinology (2004) 1.00
Cell-cell interactions in the control of spermatogenesis as studied using Leydig cell destruction and testosterone replacement. Am J Anat (1990) 1.00
Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen. J Androl (2004) 1.00
Normal male sexual differentiation and aetiology of disorders of sex development. Best Pract Res Clin Endocrinol Metab (2011) 0.98
FSH beta gene mutations in a female with partial breast development and a male sibling with normal puberty and azoospermia. J Clin Endocrinol Metab (2002) 0.97
Inhibitory and stimulatory regulation of testicular inhibin B secretion by luteinizing hormone and follicle-stimulating hormone, respectively, in the rhesus monkey (Macaca mulatta). Endocrinology (2003) 0.97
Hypogonadism in a patient with a mutation in the luteinizing hormone beta-subunit gene. N Engl J Med (2004) 0.96
Dynamics of the follicle-stimulating hormone (FSH)-inhibin B feedback loop and its role in regulating spermatogenesis in the adult male rhesus monkey (Macaca mulatta) as revealed by unilateral orchidectomy. Endocrinology (2000) 0.96
Adult height after ketoconazole treatment in patients with familial male-limited precocious puberty. J Clin Endocrinol Metab (2004) 0.95
Developmental and reproductive toxicology studies in nonhuman primates. Birth Defects Res B Dev Reprod Toxicol (2009) 0.95
Regulation of spermatogenesis: an evolutionary biologist's perspective. Semin Cell Dev Biol (2014) 0.95
Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors. Reproduction (2010) 0.95
Pulsatile stimulation with recombinant single chain human luteinizing hormone elicits precocious sertoli cell proliferation in the juvenile male rhesus monkey (Macaca mulatta). Biol Reprod (2000) 0.95
The effects of recombinant follicle-stimulating hormone on the restoration of spermatogenesis in the gonadotropin-releasing hormone-immunized adult rat. Endocrinology (1995) 0.94
Polymorphisms of the luteinizing hormone/chorionic gonadotropin receptor gene: association with maldescended testes and male infertility. Pharmacogenet Genomics (2008) 0.94
Immunohistochemical localization of androgen receptor in mouse testicular germ cells during fetal and postnatal development. Anat Rec (1996) 0.93
Gonadotropin-independent proliferation of the pale type A spermatogonia in the adult rhesus monkey (Macaca mulatta). Biol Reprod (2005) 0.93
Temporal and stage-specific changes in spermatogenesis of rat after gonadotropin deprivation by a potent gonadotropin-releasing hormone antagonist treatment. Endocrinology (1993) 0.92
A splice site mutation combined with a novel missense mutation of LHCGR cause male pseudohermaphroditism. Hum Mutat (2009) 0.92
The molecular basis of impaired follicle-stimulating hormone action: evidence from human mutations and mouse models. Reprod Sci (2012) 0.92
Follitropin (FSH) deficiency in an infertile male due to FSHbeta gene mutation. A syndrome of normal puberty and virilization but underdeveloped testicles with azoospermia, low FSH but high lutropin and normal serum testosterone concentrations. Clin Chem Lab Med (1998) 0.91
Quantitative cytological studies of spermatogenesis in intact and hypophysectomized rats: identification of androgen-dependent stages. Endocrinology (1990) 0.90
Androgen insensitivity syndrome. Semin Reprod Med (2012) 0.90
The effects of recombinant FSH on testosterone-induced spermatogenesis in gonadotrophin-deficient (hpg) mice. J Androl (1996) 0.90
Stimulatory effects of recombinant follicle-stimulating hormone on Leydig cell function and spermatogenesis in immature hypophysectomized rats. Endocrinology (1991) 0.89
Immunization of male bonnet monkeys (M. radiata) with a recombinant FSH receptor preparation affects testicular function and fertility. Endocrinology (1997) 0.89
Luteinizing hormone receptor-mediated effects on initiation of spermatogenesis in gonadotropin-deficient (hpg) mice are replicated by testosterone. Biol Reprod (2003) 0.89
The role of androgens in the initiation of spermatogenesis in man. J Clin Endocrinol Metab (1973) 0.89
FSH and testosterone, alone or in combination, initiate testicular growth and increase the number of spermatogonia and Sertoli cells in a juvenile non-human primate (Macaca mulatta). J Endocrinol (1993) 0.89
Hypogonadism in a patient with two novel mutations of the luteinizing hormone β-subunit gene expressed in a compound heterozygous form. J Clin Endocrinol Metab (2012) 0.89
A novel transgenic model to characterize the specific effects of follicle-stimulating hormone on gonadal physiology in the absence of luteinizing hormone actions. Endocrinology (2001) 0.89
Identification of gonadotropic cells in the human pituitary by immunoperoxidase technique. Mol Cell Endocrinol (1976) 0.88
Spermatogenesis in the dog. Anat Rec (1972) 0.88
Leydig cell hypoplasia: cases with new mutations, new polymorphisms and cases without mutations in the luteinizing hormone receptor gene. Clin Endocrinol (Oxf) (2002) 0.88
Mutation analysis of the LH receptor gene in Leydig cell adenoma and hyperplasia and functional and biochemical studies of activating mutations of the LH receptor gene. J Clin Endocrinol Metab (2011) 0.88
Male hormonal contraception: concept proven, product in sight? Hum Reprod Update (2006) 0.88
Suppression of spermatogenesis in man induced by Nal-Glu gonadotropin releasing hormone antagonist and testosterone enanthate (TE) is maintained by TE alone. J Clin Endocrinol Metab (1998) 0.87
A selective monotropic elevation of FSH, but not that of LH, amplifies the proliferation and differentiation of spermatogonia in the adult rhesus monkey (Macaca mulatta). Hum Reprod (2009) 0.87
Quantitative restoration of advanced spermatogenic cells in adult male rats made azoospermic by active immunization against luteinizing hormone or gonadotropin-releasing hormone. Endocrinology (1989) 0.87
A new LH receptor splice mutation responsible for male hypogonadism with subnormal sperm production in the propositus, and infertility with regular cycles in an affected sister. Hum Reprod (2008) 0.86
Normal spermatogenesis in a man with mutant luteinizing hormone. N Engl J Med (2009) 0.86
Novel male hormonal contraceptive combinations: the hormonal and spermatogenic effects of testosterone and levonorgestrel combined with a 5alpha-reductase inhibitor or gonadotropin-releasing hormone antagonist. J Clin Endocrinol Metab (2004) 0.86
Male LH-independent sexual precocity in a 3.5-year-old boy caused by a somatic activating mutation of the LH receptor in a Leydig cell tumor. J Clin Endocrinol Metab (2002) 0.86
Delay in sexual maturity of the follicle-stimulating hormone receptor knockout male mouse. Biol Reprod (2001) 0.86
Activating mutations of the lutropin choriogonadotropin receptor in precocious puberty. Receptors Channels (2002) 0.86
Testicular phenotype in luteinizing hormone receptor knockout animals and the effect of testosterone replacement therapy. Biol Reprod (2004) 0.85