Published in Schizophr Bull on September 30, 2015
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol (2002) 82.19
Most mammalian mRNAs are conserved targets of microRNAs. Genome Res (2008) 37.16
Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature (2010) 22.04
Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev (2006) 15.20
Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell (2005) 9.01
Modulation of microRNA processing by p53. Nature (2009) 7.88
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
A novel and universal method for microRNA RT-qPCR data normalization. Genome Biol (2009) 6.25
GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits. Cell (1996) 4.76
Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nat Med (2006) 4.00
microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol (2007) 3.26
RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature (1996) 3.20
Schizophrenia is a cognitive illness: time for a change in focus. JAMA Psychiatry (2013) 3.16
Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia. Mol Psychiatry (2007) 2.91
The influence of chronic exposure to antipsychotic medications on brain size before and after tissue fixation: a comparison of haloperidol and olanzapine in macaque monkeys. Neuropsychopharmacology (2005) 2.37
Increased cortical kynurenate content in schizophrenia. Biol Psychiatry (2001) 2.27
Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia. Mol Psychiatry (2003) 2.18
Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. J Neurosci (2005) 2.18
Schizophrenia is associated with an increase in cortical microRNA biogenesis. Mol Psychiatry (2009) 2.16
RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha. Proc Natl Acad Sci U S A (1997) 2.14
MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response. EMBO J (2009) 2.06
Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia. Mol Psychiatry (2001) 1.94
Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia. Neurosci Lett (2001) 1.89
Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia. Biol Psychiatry (2009) 1.71
Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia. Mol Psychiatry (2006) 1.62
NMDA receptor and schizophrenia: a brief history. Schizophr Bull (2012) 1.59
Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia. Biol Psychiatry (2010) 1.58
NMDA receptor hypofunction, parvalbumin-positive neurons, and cortical gamma oscillations in schizophrenia. Schizophr Bull (2012) 1.57
Effect of chronic antipsychotic exposure on astrocyte and oligodendrocyte numbers in macaque monkeys. Biol Psychiatry (2007) 1.57
Lamina-specific abnormalities of NMDA receptor-associated postsynaptic protein transcripts in the prefrontal cortex in schizophrenia and bipolar disorder. Neuropsychopharmacology (2007) 1.56
Altered Expression of CDC42 Signaling Pathway Components in Cortical Layer 3 Pyramidal Cells in Schizophrenia. Biol Psychiatry (2015) 1.56
Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability. Biol Psychiatry (2014) 1.55
Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics. J Neurosci (1996) 1.50
Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule-dependent mechanism. J Neurosci (2005) 1.49
Deficits in transcriptional regulators of cortical parvalbumin neurons in schizophrenia. Am J Psychiatry (2012) 1.40
Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Mol Psychiatry (2006) 1.30
Alterations in metabotropic glutamate receptor 1α and regulator of G protein signaling 4 in the prefrontal cortex in schizophrenia. Am J Psychiatry (2010) 1.30
Identification of differentially expressed microRNAs across the developing human brain. Mol Psychiatry (2013) 1.30
Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia. Mol Psychiatry (2012) 1.27
Segregation of serotonin 5-HT2A and 5-HT3 receptors in inhibitory circuits of the primate cerebral cortex. J Comp Neurol (2000) 1.22
Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes. Arch Gen Psychiatry (2011) 1.22
Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia. Mol Psychiatry (2012) 1.18
Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex. Neuron (2012) 1.17
Tissue preparation and banking. Prog Brain Res (2006) 1.16
Regional alterations in RGS4 protein in schizophrenia. Synapse (2006) 1.15
Distribution of mGluR1alpha and mGluR5 immunolabeling in primate prefrontal cortex. J Comp Neurol (2003) 1.13
Developmental regulation of the NMDA receptor subunits, NR3A and NR1, in human prefrontal cortex. Cereb Cortex (2008) 1.09
Determining the role of microRNAs in psychiatric disorders. Nat Rev Neurosci (2015) 1.09
N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia. Am J Psychiatry (2001) 1.08
Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin. Proc Natl Acad Sci U S A (2006) 1.06
Cortical opioid markers in schizophrenia and across postnatal development. Cereb Cortex (2011) 1.06
Promoter specific alterations of brain-derived neurotrophic factor mRNA in schizophrenia. Neuroscience (2010) 1.05
Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder. Mol Psychiatry (2015) 0.99
Lower glutamic acid decarboxylase 65-kDa isoform messenger RNA and protein levels in the prefrontal cortex in schizoaffective disorder but not schizophrenia. Biol Psychiatry (2014) 0.98
Dopamine D1 and D5 receptors are localized to discrete populations of interneurons in primate prefrontal cortex. Cereb Cortex (2008) 0.97
Abnormal hippocampal BDNF and miR-16 expression is associated with depression-like behaviors induced by stress during early life. PLoS One (2012) 0.96
RGS4 modulates serotonin signaling in prefrontal cortex and links to serotonin dysfunction in a rat model of schizophrenia. Mol Pharmacol (2007) 0.94
Regulator of G protein signaling 4 [corrected] is a crucial modulator of antidepressant drug action in depression and neuropathic pain models. Proc Natl Acad Sci U S A (2013) 0.94
MicroRNA and Posttranscriptional Dysregulation in Psychiatry. Biol Psychiatry (2014) 0.93
RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity. Hum Mol Genet (2006) 0.93
Quantification of D1 and D5 dopamine receptor localization in layers I, III, and V of Macaca mulatta prefrontal cortical area 9: coexpression in dendritic spines and axon terminals. J Comp Neurol (2008) 0.92
Mapping the regulator of G protein signaling 4 (RGS4): presynaptic and postsynaptic substrates for neuroregulation in prefrontal cortex. Cereb Cortex (2009) 0.90
Elevated GRIA1 mRNA expression in Layer II/III and V pyramidal cells of the DLPFC in schizophrenia. Schizophr Res (2007) 0.89
In-Silico Algorithms for the Screening of Possible microRNA Binding Sites and Their Interactions. Curr Genomics (2013) 0.88
Evaluation of TrkB and BDNF transcripts in prefrontal cortex, hippocampus, and striatum from subjects with schizophrenia, bipolar disorder, and major depressive disorder. Neurobiol Dis (2015) 0.85
Maturation of the human dorsolateral prefrontal cortex coincides with a dynamic shift in microRNA expression. Schizophr Bull (2013) 0.84
RNA-binding protein HuR regulates RGS4 mRNA stability in rabbit colonic smooth muscle cells. Am J Physiol Cell Physiol (2010) 0.83
The impact of genome wide supported microRNA-137 (MIR137) risk variants on frontal and striatal white matter integrity, neurocognitive functioning, and negative symptoms in schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2015) 0.81
Brain RGS4 and RGS10 protein expression in schizophrenia and depression. Effect of drug treatment. Psychopharmacology (Berl) (2012) 0.81
Confounders of excessive brain volume loss in schizophrenia. Neurosci Biobehav Rev (2012) 0.80
Recent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs). Int J Mol Sci (2014) 0.80
Regulator of G-protein signalling 4 expression is not altered in the prefrontal cortex in schizophrenia. Aust N Z J Psychiatry (2008) 0.78
Characterization of regulators of G-protein signaling RGS4 and RGS10 proteins in the postmortem human brain. Neurochem Int (2010) 0.78
G-protein-coupled receptor heteromers as key players in the molecular architecture of the central nervous system. CNS Neurosci Ther (2014) 0.78