Chronic inflammation of the placenta: definition, classification, pathogenesis, and clinical significance.

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Published in Am J Obstet Gynecol on October 01, 2015

Authors

Chong Jai Kim1, Roberto Romero2, Piya Chaemsaithong3, Jung-Sun Kim4

Author Affiliations

1: Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea; Perinatology Research Branch, Program for Perinatal Research and Obstetrics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, and Detroit, MI.
2: Perinatology Research Branch, Program for Perinatal Research and Obstetrics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, and Detroit, MI; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI; Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI. Electronic address: romeror@mail.nih.gov.
3: Perinatology Research Branch, Program for Perinatal Research and Obstetrics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, and Detroit, MI; Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI.
4: Perinatology Research Branch, Program for Perinatal Research and Obstetrics, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, and Detroit, MI; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med (1993) 4.94

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Preterm labor: one syndrome, many causes. Science (2014) 2.61

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Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset. Immunology (2004) 2.51

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CXC chemokines: the regulatory link between inflammation and angiogenesis. Trends Immunol (2004) 1.77

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Villitis of unknown etiology is associated with major infiltration of fetal tissue by maternal inflammatory cells. Am J Pathol (1993) 1.28

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Regulatory T cells and their role in pregnancy. Am J Reprod Immunol (2010) 1.27

Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease. J Immunol (2009) 1.27

Prenatal medicine: the child is the father of the man. 1996. J Matern Fetal Neonatal Med (2009) 1.24

HLA-specific antibodies developed in the first year posttransplant are predictive of chronic rejection and renal graft loss. Transplantation (2009) 1.23

Multiple pathways to allograft rejection. Transplantation (2002) 1.21

Donor-specific antibodies adversely affect kidney allograft outcomes. J Am Soc Nephrol (2012) 1.21

Progesterone and maintenance of pregnancy: is progesterone nature's immunosuppressant? Ann N Y Acad Sci (1977) 1.20

Placenta-derived soluble MHC class I chain-related molecules down-regulate NKG2D receptor on peripheral blood mononuclear cells during human pregnancy: a possible novel immune escape mechanism for fetal survival. J Immunol (2006) 1.19

Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis. Am J Transplant (2009) 1.18

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Functionally important disorders of the placenta, umbilical cord, and fetal membranes. Hum Pathol (1987) 1.12

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Severe fetal placental vascular lesions in term infants with neurologic impairment. Am J Obstet Gynecol (2005) 1.11

Inflammatory lesions of the human placenta. III. The histopathology of villitis of unknown aetiology. Placenta (1981) 1.11

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Elevated interleukin-8 concentrations in amniotic fluid of mothers whose neonates subsequently develop bronchopulmonary dysplasia. Eur J Obstet Gynecol Reprod Biol (1998) 1.11

Immunological relationship between the mother and the fetus. Int Rev Immunol (2003) 1.10

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A signature of maternal anti-fetal rejection in spontaneous preterm birth: chronic chorioamnionitis, anti-human leukocyte antigen antibodies, and C4d. PLoS One (2011) 1.10

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A lesson in tolerance--maternal instruction to fetal cells. N Engl J Med (2009) 1.09

Kinetics of gene expression in murine cutaneous graft-versus-host disease. Am J Pathol (2004) 1.08

Gene expression profiling of bronchoalveolar lavage cells in acute lung rejection. Am J Respir Crit Care Med (2003) 1.07

Placental villitis of unknown origin: epidemiologic associations. Am J Obstet Gynecol (2005) 1.07

Exosomes secreted by human placenta carry functional Fas ligand and TRAIL molecules and convey apoptosis in activated immune cells, suggesting exosome-mediated immune privilege of the fetus. J Immunol (2013) 1.06

Clinical and pathologic aspects of recurrent placental villitis. Hum Pathol (1985) 1.06

Complement regulatory proteins at the feto-maternal interface during human placental development: distribution of CD59 by comparison with membrane cofactor protein (CD46) and decay accelerating factor (CD55). Eur J Immunol (1992) 1.06