Chromosome transplantation as a novel approach for correcting complex genomic disorders.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 26485770)

Published in Oncotarget on November 03, 2015

Authors

Marianna Paulis1,2, Alessandra Castelli1,2, Lucia Susani1,2, Michela Lizier2,3, Irina Lagutina4, Maria Luisa Focarelli1,2, Camilla Recordati5, Paolo Uva6, Francesca Faggioli1,2, Tui Neri1,2, Eugenio Scanziani5,7, Cesare Galli4,8, Franco Lucchini3, Anna Villa1,2, Paolo Vezzoni1,2

Author Affiliations

1: Milan Unit, Istituto di Ricerca Genetica e Biomedica, CNR, Milan, Italy.
2: Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
3: Centro Ricerche Biotecnologiche, Università Cattolica del Sacro Cuore, Cremona, Italy.
4: Avantea, Cremona, Italy.
5: Mouse and Animal Pathology Laboratory, Fondazione Filarete, Milan, Italy.
6: CRS4 Bioinformatics Laboratory, Parco Scientifico e Tecnologico POLARIS, Pula, Cagliari, Italy.
7: Department of Veterinary Sciences and Public Health, University of Milan, Milan, Italy.
8: Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.

Articles cited by this

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature (1987) 10.32

Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits. Trends Genet (1998) 7.93

THREE DEGREES OF GUANYLIC ACID--INOSINIC ACID PYROPHOSPHORYLASE DEFICIENCY IN MOUSE FIBROBLASTS. Nature (1964) 4.67

Human oocytes reprogram somatic cells to a pluripotent state. Nature (2011) 4.03

A customized and versatile high-density genotyping array for the mouse. Nat Methods (2009) 3.53

Gene therapy: twenty-first century medicine. Annu Rev Biochem (2005) 2.59

Global hypomethylation of the genome in XX embryonic stem cells. Nat Genet (2005) 2.35

Functional expression and germline transmission of a human chromosome fragment in chimaeric mice. Nat Genet (1997) 2.28

Cloned transchromosomic calves producing human immunoglobulin. Nat Biotechnol (2002) 2.13

A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency. Nucleic Acids Res (1992) 1.96

Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature (2014) 1.66

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells. Proc Natl Acad Sci U S A (2012) 1.62

High frequency DNA rearrangements associated with mouse centromeric satellite DNA. J Mol Biol (1986) 1.54

Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy. Sci Transl Med (2011) 1.51

Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias. BMC Genomics (2012) 1.39

Trisomy correction in Down syndrome induced pluripotent stem cells. Cell Stem Cell (2012) 1.35

Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology. Expert Opin Drug Deliv (2014) 1.26

Targeted chromosome elimination from ES-somatic hybrid cells. Nat Methods (2006) 1.20

Preparation of microcells by enucleation of micronucleate cells. Exp Cell Res (1974) 1.20

New method for culture of zona-included or zona-free embryos: the Well of the Well (WOW) system. Mol Reprod Dev (2000) 1.19

Molecular studies of chromosomal mosaicism: relative frequency of chromosome gain or loss and possible role of cell selection. Am J Hum Genet (1995) 1.17

Microcell-mediated chromosome transfer (MMCT): small cells with huge potential. Mamm Genome (2003) 1.03

Handmade somatic cell cloning in cattle: analysis of factors contributing to high efficiency in vitro. Biol Reprod (2003) 0.94

Human mini-chromosomes in mouse embryonal stem cells. Hum Mol Genet (1997) 0.89

Transfer of a human chromosomal vector from a hamster cell line to a mouse embryonic stem cell line. Stem Cells (2007) 0.83

A simple genotyping assay for the Hprt null allele in mice produced from the HM-1 and E14TG2a mouse embryonic stem cell lines. Transgenic Res (2003) 0.81

Chromosome transfer via cell fusion. Methods Mol Biol (2011) 0.80

Target chromosomes of inducible deletion by a Cre/inverted loxP system in mouse embryonic stem cells. Chromosome Res (2009) 0.80

A pre-screening FISH-based method to detect CRISPR/Cas9 off-targets in mouse embryonic stem cells. Sci Rep (2015) 0.80