Effect of fibulin-5 on adhesion, migration and invasion of hepatocellular carcinoma cells via an integrin-dependent mechanism.

Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/β-catenin signaling pathway. Oncotarget (2017) 0.75

Hepatocellular carcinoma. Lancet (2012) 18.09

Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature (2002) 3.60

Metastasis mechanisms. Biochim Biophys Acta (2009) 2.51

DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries. J Biol Chem (1999) 1.62

Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. J Biol Chem (2002) 1.58

The integrin adhesome: from genes and proteins to human disease. Nat Rev Mol Cell Biol (2014) 1.57

Downregulation of several fibulin genes in prostate cancer. Prostate (2007) 1.46

Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-beta in mammary epithelial cells via a MMP-dependent mechanism. Carcinogenesis (2008) 1.45

Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression. Cancer Res (2009) 1.25

Fibulin-5 binds human smooth-muscle cells through alpha5beta1 and alpha4beta1 integrins, but does not support receptor activation. Biochem J (2007) 1.21

Fibulin-5 antagonizes vascular endothelial growth factor (VEGF) signaling and angiogenic sprouting by endothelial cells. DNA Cell Biol (2004) 1.20

Structural requirements for alpha 9 beta 1-mediated adhesion and migration to thrombin-cleaved osteopontin. Exp Cell Res (1998) 1.18

DKK1 promotes hepatocellular carcinoma cell migration and invasion through β-catenin/MMP7 signaling pathway. Mol Cancer (2013) 1.11

Matricellular proteins: a sticky affair with cancers. J Oncol (2012) 1.10

Fibronectin's central cell-binding domain supports focal adhesion formation and Rho signal transduction. J Biol Chem (2005) 1.07

Fibulin-5 function during tumorigenesis. Future Oncol (2005) 1.05

Loss of fibulin-5 binding to beta1 integrins inhibits tumor growth by increasing the level of ROS. Dis Model Mech (2010) 1.04

Protocadherin 17 acts as a tumour suppressor inducing tumour cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers. J Pathol (2013) 0.97

Oncogenic fibulin-5 promotes nasopharyngeal carcinoma cell metastasis through the FLJ10540/AKT pathway and correlates with poor prognosis. PLoS One (2013) 0.97

Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells. Cell Biosci (2014) 0.91

Fibulin-5 inhibits hepatocellular carcinoma cell migration and invasion by down-regulating matrix metalloproteinase-7 expression. BMC Cancer (2014) 0.90

Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-β signaling. J Biol Chem (2013) 0.88

Retracted Inhibition of fibroblast growth factor receptor signaling impairs metastasis of hepatocellular carcinoma. Tumour Biol (2014) 0.84

Cellular mechanotransduction: sensing rigidity. Nat Mater (2014) 0.82

[Diverse functions of fibulin-5 in tumors]. Mol Biol (Mosk) (2015) 0.77