Sympathetic autonomic dysfunction and impaired cardiovascular performance in higher risk surgical patients: implications for perioperative sympatholysis.

PubWeight™: 0.78‹?›

🔗 View Article (PMC 4620232)

Published in Open Heart on October 19, 2015

Authors

John Whittle1, Alexander Nelson2, James M Otto3, Robert C M Stephens4, Daniel S Martin3, J Robert Sneyd5, Richard Struthers5, Gary Minto5, Gareth L Ackland6

Author Affiliations

1: Division of Medicine, Department of Clinical Physiology , University College London , London , UK.
2: UCL Medical School, University College London , London , UK.
3: Division of Surgery and Interventional Science , University College London, Royal Free Hospital , London , UK.
4: Department of Anaesthesia , University College London Hospitals NHS Trust , London , UK.
5: Plymouth University, Peninsula Schools of Medicine and Dentistry, Plymouth , London , UK.
6: Division of Medicine, Department of Clinical Physiology , University College London , London , UK ; Department of Neuroscience, Physiology and Pharmacology , Centre for Cardiovascular and Metabolic Neuroscience, University College London , London , UK ; William Harvey Research Institute, Queen Mary University of London, London, UK.

Articles cited by this

Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet (2008) 13.15

ATS/ACCP Statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med (2003) 8.83

A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol (1985) (1986) 8.01

2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol (2012) 4.77

Cardiopulmonary exercise testing predicts 5 yr survival after major surgery. Br J Anaesth (2012) 4.65

Goal-directed intraoperative fluid administration reduces length of hospital stay after major surgery. Anesthesiology (2002) 4.10

Perioperative beta blockade in noncardiac surgery: a systematic review for the 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines. J Am Coll Cardiol (2014) 2.85

Individualised oxygen delivery targeted haemodynamic therapy in high-risk surgical patients: a multicentre, randomised, double-blind, controlled, mechanistic trial. Lancet Respir Med (2014) 2.76

The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress. N Engl J Med (1991) 2.74

Meta-analysis of secure randomised controlled trials of β-blockade to prevent perioperative death in non-cardiac surgery. Heart (2013) 2.61

Mental stress and the induction of silent myocardial ischemia in patients with coronary artery disease. N Engl J Med (1988) 2.61

Predicted values for clinical exercise testing. Am Rev Respir Dis (1984) 2.58

Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature (2007) 2.56

Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes. Lancet (2003) 2.56

Mental stress induces transient endothelial dysfunction in humans. Circulation (2000) 2.37

Clonidine in patients undergoing noncardiac surgery. N Engl J Med (2014) 2.07

Silent myocardial ischaemia due to mental stress. Lancet (1984) 1.91

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature (2011) 1.64

Excessive heart rate increase during mild mental stress in preparation for exercise predicts sudden death in the general population. Eur Heart J (2009) 1.61

Perioperative beta blockade: where do we go from here? Lancet (2008) 1.59

Assessing fitness for surgery: a comparison of questionnaire, incremental shuttle walk, and cardiopulmonary exercise testing in general surgical patients. Br J Anaesth (2008) 1.59

Ventilatory and cardiovascular responses to inspired He-O2 during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (1998) 1.53

Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes. Anesthesiology (2014) 1.47

Intraoperative tachycardia and hypertension are independently associated with adverse outcome in noncardiac surgery of long duration. Anesth Analg (2002) 1.38

Exercise electrocardiogram testing: beyond the ST segment. Circulation (2006) 1.32

Submaximal cardiopulmonary exercise testing predicts complications and hospital length of stay in patients undergoing major elective surgery. Ann Surg (2010) 1.32

Cardioprotection, attenuated systemic inflammation, and survival benefit of beta1-adrenoceptor blockade in severe sepsis in rats. Crit Care Med (2010) 1.30

Estimating exercise stroke volume from asymptotic oxygen pulse in humans. J Appl Physiol (1985) (1996) 1.22

Estimation of VO2max from the ratio between HRmax and HRrest--the Heart Rate Ratio Method. Eur J Appl Physiol (2003) 1.15

Intraoperative myocardial ischemia: localization by continuous 12-lead electrocardiography. Anesthesiology (1988) 1.14

Mental stress provokes ischemia in coronary artery disease subjects without exercise- or adenosine-induced ischemia. J Am Coll Cardiol (2006) 1.12

Exercise-induced redistribution of T lymphocytes is regulated by adrenergic mechanisms. Brain Behav Immun (2007) 1.06

Guidelines for clinical exercise testing laboratories. A statement for healthcare professionals from the Committee on Exercise and Cardiac Rehabilitation, American Heart Association. Circulation (1995) 1.06

Role of nondiagnostic exercise-induced ST-segment abnormalities in predicting future coronary events in asymptomatic volunteers. Circulation (2002) 0.99

Cardiopulmonary exercise testing predicts postoperative outcome in patients undergoing gastric bypass surgery. Br J Anaesth (2012) 0.90

Metoprolol reduces cerebral tissue oxygen tension after acute hemodilution in rats. Anesthesiology (2009) 0.89

Preoperative cardiopulmonary exercise testing and risk of early mortality following abdominal aortic aneurysm repair. Br J Surg (2012) 0.89

Genetic variation, β-blockers, and perioperative myocardial infarction. Anesthesiology (2011) 0.87

Quo vadis, perioperative beta blockade? Are you "POISE'd" on the brink? Anesth Analg (2008) 0.85

Blood pressure management in stroke. Curr Opin Anaesthesiol (2012) 0.83

Perioperative beta-blockade, 2008: what does POISE tell us, and was our earlier caution justified? Br J Anaesth (2008) 0.83

Patients' inability to perform a preoperative cardiopulmonary exercise test or demonstrate an anaerobic threshold is associated with inferior outcomes after major colorectal surgery. Br J Anaesth (2013) 0.80

L-selectin expression affects T-cell circulation following isoproterenol infusion in humans. Brain Behav Immun (1997) 0.79

Catecholamine inotrope resuscitation of antibiotic-damaged staphylococci and its blockade by specific receptor antagonists. J Infect Dis (2008) 0.78

Mental stress opposes endothelium-dependent vasodilation in young healthy individuals. Vasc Med (2001) 0.77

Beta-adrenoreceptor modulation of metabolic, endocrine and immunologic function during critical illness. Endocr Metab Immune Disord Drug Targets (2010) 0.76

Articles by these authors

Subclinical cardiopulmonary dysfunction in stage 3 chronic kidney disease. Open Heart (2016) 0.75