PD-L1 expression is increased in monocyte derived dendritic cells in response to porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus infections.

PubWeight™: 0.76^‹?›

🔗 View Article (PMID 26553563)

Published in Vet Immunol Immunopathol on September 28, 2015

Authors

O Richmond¹, T E Cecere², E Erdogan¹, X J Meng¹, P Piñeyro¹, S Subramaniam¹, S M Todd¹, T LeRoith¹

Author Affiliations

1: Department of Biomedical Sciences and Pathobiology, Virginia Tech, Blacksburg, VA, United States.
2: Department of Biomedical Sciences and Pathobiology, Virginia Tech, Blacksburg, VA, United States. Electronic address: tcecere@vt.edu.

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The PD-L1/CD86 ratio is increased in dendritic cells co-infected with porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus, and the PD-L1/PD-1 axis is associated with anergy, apoptosis, and the induction of regulatory T-cells in porcine lymphocytes. Vet Microbiol (2015) 0.76