Published in Int J Mol Sci on November 12, 2015
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J Biomol Screen (1999) 32.67
Can the pharmaceutical industry reduce attrition rates? Nat Rev Drug Discov (2004) 15.57
Natural products as sources of new drugs over the 30 years from 1981 to 2010. J Nat Prod (2012) 13.27
Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis. Neuron (1990) 4.15
Natural products: a continuing source of novel drug leads. Biochim Biophys Acta (2013) 4.12
Micromotion of mammalian cells measured electrically. Proc Natl Acad Sci U S A (1991) 3.51
Monitoring fibroblast behavior in tissue culture with an applied electric field. Proc Natl Acad Sci U S A (1984) 2.89
Electric cell-substrate impedance sensing (ECIS) as a noninvasive means to monitor the kinetics of cell spreading to artificial surfaces. Exp Cell Res (2000) 2.45
Electrical wound-healing assay for cells in vitro. Proc Natl Acad Sci U S A (2004) 2.43
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis. Breast Cancer Res (2012) 1.65
Stem cells and drug discovery: the beginning of a new era? Cell (2008) 1.61
Neuroprotection by Brazilian Green Propolis against In vitro and In vivo Ischemic Neuronal Damage. Evid Based Complement Alternat Med (2005) 1.59
Bioelectrical impedance assay to monitor changes in cell shape during apoptosis. Biosens Bioelectron (2004) 1.24
Neuronal apoptosis induced by pharmacological concentrations of 3-hydroxykynurenine: characterization and protection by dantrolene and Bcl-2 overexpression. J Neurochem (2000) 1.22
Water extract of propolis and its main constituents, caffeoylquinic acid derivatives, exert neuroprotective effects via antioxidant actions. Life Sci (2006) 1.21
A label-free photonic crystal biosensor imaging method for detection of cancer cell cytotoxicity and proliferation. Apoptosis (2007) 1.15
Assessment of cytotoxicity using electric cell-substrate impedance sensing: concentration and time response function approach. Anal Chem (2002) 1.12
Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay. Planta Med (2002) 1.12
Assessing nanotoxicity in cells in vitro. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.05
Use of electric cell-substrate impedance sensing to assess in vitro cytotoxicity. Biosens Bioelectron (2009) 1.02
On-line monitoring of cell growth and cytotoxicity using electric cell-substrate impedance sensing (ECIS). Biotechnol Prog (2003) 1.01
Reduction of MTT by aqueous herbal extracts in the absence of cells. J Ethnopharmacol (2004) 1.01
The importance of polymerization and galloylation for the antiproliferative properties of procyanidin-rich natural extracts. FEBS J (2007) 1.01
Procyanidin fractions from pine (Pinus pinaster) bark: radical scavenging power in solution, antioxidant activity in emulsion, and antiproliferative effect in melanoma cells. J Agric Food Chem (2005) 0.93
Back to basics: label-free technologies for small molecule screening. Comb Chem High Throughput Screen (2008) 0.92
Food supplementation with an olive (Olea europaea L.) leaf extract reduces blood pressure in borderline hypertensive monozygotic twins. Phytother Res (2008) 0.92
Effects of (-)-epigallocatechin gallate on RPE cell migration and adhesion. Mol Vis (2010) 0.90
Zeaxanthin inhibits PDGF-BB-induced migration in human dermal fibroblasts. Exp Dermatol (2010) 0.90
Influence of silymarin and its flavonolignans on H(2)O(2)-induced oxidative stress in human keratinocytes and mouse fibroblasts. Burns (2006) 0.89
Cytotoxicity screening of Bangladeshi medicinal plant extracts on pancreatic cancer cells. BMC Complement Altern Med (2010) 0.88
Electric cell-substrate impedance sensing (ECIS) based real-time measurement of titer dependent cytotoxicity induced by adenoviral vectors in an IPI-2I cell culture model. Biosens Bioelectron (2010) 0.85
Flavonoids, flavonoid metabolites, and phenolic acids inhibit oxidative stress in the neuronal cell line HT-22 monitored by ECIS and MTT assay: a comparative study. J Nat Prod (2013) 0.83
Monitoring viral-induced cell death using electric cell-substrate impedance sensing. Biosens Bioelectron (2007) 0.83
High-throughput fluorescence polarization method for identification of FKBP12 ligands. J Biomol Screen (2002) 0.83
Elucidation of mechanisms underlying the protective effects of olive leaf extract against lead-induced neurotoxicity in Wistar rats. J Toxicol Sci (2011) 0.82
Cytotoxic effects of oxysterols produced during ozonolysis of cholesterol in murine GT1-7 hypothalamic neurons. Free Radic Res (2007) 0.82
Use of cellular electrical impedance sensing to assess in vitro cytotoxicity of anticancer drugs in a human kidney cell nephrotoxicity model. Analyst (2012) 0.82
Free radical scavenging activities measured by electron spin resonance spectroscopy and B16 cell antiproliferative behaviors of seven plants. J Agric Food Chem (2001) 0.82
Molecular angiogenic events of a two-herb wound healing formula involving MAPK and Akt signaling pathways in human vascular endothelial cells. Wound Repair Regen (2013) 0.82
Antitumour effects of Yangzheng Xiaoji in human osteosarcoma: the pivotal role of focal adhesion kinase signalling. Oncol Rep (2013) 0.81
Modification of glutamate-induced oxidative stress by lead: the role of extracellular calcium. Free Radic Biol Med (1998) 0.80
Cytoprotective effects of silymarin on epithelial cells against arsenic-induced apoptosis in contrast with quercetin cytotoxicity. Life Sci (2010) 0.80
Neuroprotective effects of nicergoline in immortalized neurons. Eur J Pharmacol (1999) 0.80
Birch inner bark procyanidins can be resolved with enhanced sensitivity by hydrophilic interaction HPLC-MS. J Sep Sci (2011) 0.80
Antimicrobial and cytotoxic activity of red propolis: an alert for its safe use. J Appl Microbiol (2015) 0.79
Cytotoxicity Effects of Amoora rohituka and chittagonga on Breast and Pancreatic Cancer Cells. Evid Based Complement Alternat Med (2011) 0.79
Quantitative analysis of polymeric proanthocyanidins in birch leaves with normal-phase HPLC. Phytochem Anal (2006) 0.78
Quality evaluation of different preparations of dry extracts of birch (Betula pendula Roth) leaves. Nat Prod Res (2014) 0.78
GT1-7 cell-based cytoxicity screening assay on 96-well microplates as a platform for the safety assessment of genetically modified Gerbera hybrida extracts. Drug Chem Toxicol (2009) 0.77
Effect of beta-amyloid on endothelial cells: lack of direct toxicity, enhancement of MTT-induced cell death and intracellular accumulation. Neurochem Int (2003) 0.77
How to translate a bioassay into a screening assay for natural products: general considerations and implementation of antimicrobial screens. Planta Med (2014) 0.77
Silybum marianum (milk thistle) in the management and prevention of hepatotoxicity in a patient undergoing reinduction therapy for acute myelogenous leukemia. J Oncol Pharm Pract (2012) 0.76
Anticancer diarylheptanoid glycosides from the inner bark of Betula papyrifera. Phytochemistry (2007) 0.76