Published in Biorheology on November 19, 2015
Acquired von Willebrand syndrome associated with left ventricular assist device. Blood (2016) 0.88
Segmental outflow of aqueous humor in mouse and human. Exp Eye Res (2016) 0.75
Biochemistry and genetics of von Willebrand factor. Annu Rev Biochem (1998) 6.14
Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell (1996) 5.12
Consideration of the Possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues. Biochemistry (1975) 4.65
ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions. Blood (2002) 4.52
Platelets and shear stress. Blood (1996) 4.18
Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor. Science (2009) 3.85
Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion. Blood (1996) 3.36
Shear-induced unfolding triggers adhesion of von Willebrand factor fibers. Proc Natl Acad Sci U S A (2007) 3.24
Shear-dependent changes in the three-dimensional structure of human von Willebrand factor. Blood (1996) 2.75
Amino acid sequence of human von Willebrand factor. Biochemistry (1986) 2.73
Rheological aspects of thrombosis and haemostasis: basic principles and applications. ICTH-Report--Subcommittee on Rheology of the International Committee on Thrombosis and Haemostasis. Thromb Haemost (1986) 2.54
Platelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF. J Clin Invest (2008) 2.43
Occurrence and role of cis peptide bonds in protein structures. J Mol Biol (1990) 2.06
Integrin alpha(v)beta(3) on human endothelial cells binds von Willebrand factor strings under fluid shear stress. Blood (2008) 2.04
Arterial thrombosis--insidious, unpredictable and deadly. Nat Med (2011) 1.96
Aspects of hydrodynamic shear regulating shear-induced platelet activation and self-association of von Willebrand factor in suspension. Blood (2002) 1.95
Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor. Proc Natl Acad Sci U S A (2009) 1.91
A mechanically stabilized receptor-ligand flex-bond important in the vasculature. Nature (2010) 1.90
The distribution of blood rheological parameters in the microvasculature of cat mesentery. Circ Res (1978) 1.89
Localization of ADAMTS13 to the stellate cells of human liver. Blood (2005) 1.85
Purified A2 domain of von Willebrand factor binds to the active conformation of von Willebrand factor and blocks the interaction with platelet glycoprotein Ibalpha. J Thromb Haemost (2007) 1.85
Interaction forces between red cells agglutinated by antibody. I. Theoretical. Biophys J (1986) 1.81
von Willebrand factor self-association on platelet GpIbalpha under hydrodynamic shear: effect on shear-induced platelet activation. Blood (2010) 1.75
Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress. Blood (2007) 1.71
Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions. J Thromb Haemost (2008) 1.68
A novel human metalloprotease synthesized in the liver and secreted into the blood: possibly, the von Willebrand factor-cleaving protease? J Biochem (2001) 1.67
Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa. Blood (1987) 1.57
Substructure of human von Willebrand factor. J Clin Invest (1985) 1.55
Functional self-association of von Willebrand factor during platelet adhesion under flow. Proc Natl Acad Sci U S A (2001) 1.51
ADAMTS13 is expressed in hepatic stellate cells. Lab Invest (2005) 1.49
Proteolytic inactivation of ADAMTS13 by thrombin and plasmin. Blood (2004) 1.36
Thrombospondin-1 controls vascular platelet recruitment and thrombus adherence in mice by protecting (sub)endothelial VWF from cleavage by ADAMTS13. Blood (2005) 1.35
Hydrodynamic forces applied on intercellular bonds, soluble molecules, and cell-surface receptors. Biophys J (2004) 1.35
P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface. Blood (2003) 1.34
Shielding of the A1 domain by the D'D3 domains of von Willebrand factor modulates its interaction with platelet glycoprotein Ib-IX-V. J Biol Chem (2005) 1.34
A pH-regulated dimeric bouquet in the structure of von Willebrand factor. EMBO J (2011) 1.34
Human endothelial cells synthesize and release ADAMTS-13. J Thromb Haemost (2006) 1.33
Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor. Blood (2011) 1.33
Estimating the efficiency of cell capture and arrest in flow chambers: study of neutrophil binding via E-selectin and ICAM-1. Biophys J (2002) 1.33
Solution structure of human von Willebrand factor studied using small angle neutron scattering. J Biol Chem (2006) 1.33
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice. J Clin Invest (2011) 1.32
Soluble plasma-derived von Willebrand factor assembles to a haemostatically active filamentous network. Thromb Haemost (2007) 1.32
Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site. Blood (2009) 1.32
Platelet-derived VWF-cleaving metalloprotease ADAMTS-13. J Thromb Haemost (2005) 1.31
Detection of von Willebrand factor-cleaving protease (ADAMTS-13) in human platelets. Biochem Biophys Res Commun (2004) 1.29
Apical sorting of ADAMTS13 in vascular endothelial cells and Madin-Darby canine kidney cells depends on the CUB domains and their association with lipid rafts. Blood (2006) 1.29
Cloning, expression, and functional characterization of the von Willebrand factor-cleaving protease (ADAMTS13). Blood (2002) 1.29
Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13. Blood (2009) 1.27
Sequence and structure relationships within von Willebrand factor. Blood (2012) 1.26
N-linked glycosylation of VWF modulates its interaction with ADAMTS13. Blood (2007) 1.24
Shear-induced disulfide bond formation regulates adhesion activity of von Willebrand factor. J Biol Chem (2007) 1.24
Calcium modulates force sensing by the von Willebrand factor A2 domain. Nat Commun (2011) 1.22
Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding. Structure (1997) 1.20
Hydrodynamic shear shows distinct roles for LFA-1 and Mac-1 in neutrophil adhesion to intercellular adhesion molecule-1. Blood (1998) 1.20
An explanation for the rare occurrence of cis peptide units in proteins and polypeptides. J Mol Biol (1976) 1.19
Contribution of platelet vs. endothelial VWF to platelet adhesion and hemostasis. J Thromb Haemost (2012) 1.09
A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13. Blood (2011) 1.06
Modeling the reversible kinetics of neutrophil aggregation under hydrodynamic shear. Biophys J (1997) 1.06
Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice. J Biol Chem (2004) 1.05
Force-induced prolyl cis-trans isomerization in elastin-like polypeptides. J Am Chem Soc (2007) 1.04
Direct observation of von Willebrand factor elongation and fiber formation on collagen during acute whole blood exposure to pathological flow. Arterioscler Thromb Vasc Biol (2012) 1.03
Fluid shear induces conformation change in human blood protein von Willebrand factor in solution. Biophys J (2009) 1.03
Effects of plasmin on von Willebrand factor multimers. Degradation in vitro and stimulation of release in vivo. J Clin Invest (1985) 1.03
Allosteric activation of ADAMTS13 by von Willebrand factor. Proc Natl Acad Sci U S A (2014) 1.02
The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story. J Thromb Haemost (2013) 1.02
Conformational activation of ADAMTS13. Proc Natl Acad Sci U S A (2014) 1.01
Nonlinear flow affects hydrodynamic forces and neutrophil adhesion rates in cone-plate viscometers. Biophys J (2001) 0.99
The plasma von Willebrand factor O-glycome comprises a surprising variety of structures including ABH antigens and disialosyl motifs. J Thromb Haemost (2009) 0.96
Formation of platelet strings and microthrombi in the presence of ADAMTS-13 inhibitor does not require P-selectin or beta3 integrin. J Thromb Haemost (2006) 0.93
Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain. Blood (2011) 0.93
The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels. Blood (2013) 0.92
Surface dependent structures of von Willebrand factor observed by AFM under aqueous conditions. Colloids Surf B Biointerfaces (2000) 0.91
Effect of secondary flow on biological experiments in the cone-plate viscometer: methods for estimating collision frequency, wall shear stress and inter-particle interactions in non-linear flow. Biorheology (2001) 0.90
Mapping the N-glycome of human von Willebrand factor. Biochem J (2012) 0.90
von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion. Blood (2012) 0.89
Carboxyl terminus of ADAMTS13 directly inhibits platelet aggregation and ultra large von Willebrand factor string formation under flow in a free-thiol-dependent manner. Arterioscler Thromb Vasc Biol (2013) 0.88
Shear-dependent morphology of von Willebrand factor bound to immobilized collagen. Blood (2002) 0.87
O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions. Blood (2012) 0.87
Shear-stress-induced conformational changes of von Willebrand factor in a water-glycerol mixture observed with single molecule microscopy. J Phys Chem B (2014) 0.87
Impact of O-linked glycosylation of the VWF-A1-domain flanking regions on platelet interaction. Br J Haematol (2005) 0.86
Phenotypic expression of ADAMTS13 in glomerular endothelial cells. PLoS One (2011) 0.86
Application of fluorescence spectroscopy to quantify shear-induced protein conformation change. Biophys J (2009) 0.86
Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5. Haematologica (2012) 0.86
Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF. Blood (2014) 0.85
Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro. Thromb Res (2010) 0.84
Escherichia coli-derived von Willebrand factor-A2 domain fluorescence/Förster resonance energy transfer proteins that quantify ADAMTS13 activity. Anal Biochem (2010) 0.82
Identification of galectin-1 and galectin-3 as novel partners for von Willebrand factor. Arterioscler Thromb Vasc Biol (2012) 0.81
No evidence for a direct effect of von Willebrand factor's ABH blood group antigens on von Willebrand factor clearance. J Thromb Haemost (2015) 0.78
The O-linked glycans of human von Willebrand factor modulate its interaction with ADAMTS-13. J Thromb Haemost (2014) 0.77
Qualitative and quantitative modifications of von Willebrand factor in patients with essential thrombocythemia and controlled platelet count. J Thromb Haemost (2015) 0.76
Platelet GpIba binding to von Willebrand Factor under fluid shear:contributions of the D′D3-domain, A1-domain flanking peptide and O-linked glycans. J Am Heart Assoc (2014) 0.75