Simultaneously Detection of 50 Mutations at 20 Sites in the BRAF and RAS Genes by Multiplexed Single-Nucleotide Primer Extension Assay Using Fine-Needle Aspirates of Thyroid Nodules.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4654183)

Published in Yale J Biol Med on November 24, 2015

Authors

Aaron A Stence1, Michael P Gailey1, Robert A Robinson1, Chris S Jensen1, Deqin Ma1

Author Affiliations

1: Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

Articles cited by this

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res (2003) 8.67

The Bethesda System For Reporting Thyroid Cytopathology. Am J Clin Pathol (2009) 6.79

Thyroid incidentalomas: management approaches to nonpalpable nodules discovered incidentally on thyroid imaging. Ann Intern Med (1997) 3.44

Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: a synopsis of the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science Conference. Diagn Cytopathol (2008) 3.30

Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules. J Clin Endocrinol Metab (2009) 3.23

Molecular genetics and diagnosis of thyroid cancer. Nat Rev Endocrinol (2011) 2.96

Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples. J Clin Endocrinol Metab (2011) 2.93

RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma. J Clin Endocrinol Metab (2003) 2.72

Contribution of molecular testing to thyroid fine-needle aspiration cytology of "follicular lesion of undetermined significance/atypia of undetermined significance". Cancer Cytopathol (2010) 2.55

Thyroid nodules. Am Fam Physician (2003) 1.86

Impact of proto-oncogene mutation detection in cytological specimens from thyroid nodules improves the diagnostic accuracy of cytology. J Clin Endocrinol Metab (2010) 1.86

Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer. Oncogene (2004) 1.82

Prevalence of thyroid cancer in multinodular goiter versus single nodule: a systematic review and meta-analysis. Thyroid (2013) 1.59

Thyroid cancer in thyroid nodules: finding a needle in the haystack. Am J Med (1992) 1.51

Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes. PLoS One (2010) 1.41

Molecular analysis of thyroid tumors. Endocr Pathol (2011) 1.23

Variability in the atypia of undetermined significance/follicular lesion of undetermined significance diagnosis in the Bethesda System for Reporting Thyroid Cytopathology: sources and recommendations. Acta Cytol (2011) 1.22

New strategies in diagnosing cancer in thyroid nodules: impact of molecular markers. Clin Cancer Res (2013) 1.04

Multiplatform comparison of molecular oncology tests performed on cytology specimens and formalin-fixed, paraffin-embedded tissue. Cancer Cytopathol (2014) 0.85