Published in Cancer Sci on February 02, 2016
The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer (2012) 24.94
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science (1999) 11.04
PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature (2014) 10.39
Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol (2003) 6.95
Biliary tract cancers. N Engl J Med (1999) 6.36
Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells. Sci Transl Med (2013) 5.82
Cholangiocarcinoma. A spectrum of intrahepatic, perihilar, and distal tumors. Ann Surg (1996) 5.42
ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity (2001) 5.42
Breakthrough of the year 2013. Cancer immunotherapy. Science (2013) 5.05
Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature (2001) 4.93
Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB. Proc Natl Acad Sci U S A (1999) 4.40
Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo. Proc Natl Acad Sci U S A (2001) 3.21
Effect of NKG2D ligand expression on host immune responses. Immunol Rev (2010) 3.08
Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol (2013) 2.98
Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update. Gut (2012) 2.91
Worldwide trends in mortality from biliary tract malignancies. BMC Cancer (2002) 2.61
Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma. Clin Cancer Res (2014) 2.27
NKG2D ligands in tumor immunity. Oncogene (2008) 2.26
Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation. Cancer Discov (2014) 1.80
Reduced NKG2D ligand expression in hepatocellular carcinoma correlates with early recurrence. J Hepatol (2011) 1.68
Rising trends in cholangiocarcinoma: is the ICD classification system misleading us? J Hepatol (2011) 1.61
Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway. Trends Mol Med (2014) 1.59
NKG2D ligand expression in human colorectal cancer reveals associations with prognosis and evidence for immunoediting. Clin Cancer Res (2009) 1.50
Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: high expression of ULBP2 is an indicator of poor prognosis. Cancer Immunol Immunother (2008) 1.38
E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma. Br J Cancer (2011) 1.34
Evidence-based approach to cholangiocarcinoma: a systematic review of the current literature. J Am Coll Surg (2008) 1.25
Expression of the stress-related MHC class I chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients. Int J Cancer (2006) 1.20
ULBP2 and RAET1E NKG2D ligands are independent predictors of poor prognosis in ovarian cancer patients. Int J Cancer (2010) 1.17
NKG2D ligand tumor expression and association with clinical outcome in early breast cancer patients: an observational study. BMC Cancer (2012) 1.11
Biliary carcinoembryonic antigen levels are a marker for cholangiocarcinoma. Am J Surg (1996) 1.10
Expression, signaling proficiency, and stimulatory function of the NKG2D lymphocyte receptor in human cancer cells. Proc Natl Acad Sci U S A (2011) 0.99
Molecular Bases for the Regulation of NKG2D Ligands in Cancer. Front Immunol (2014) 0.94
Cancer exosomes and NKG2D receptor-ligand interactions: impairing NKG2D-mediated cytotoxicity and anti-tumour immune surveillance. Semin Cancer Biol (2014) 0.92
Valproic acid sensitizes pancreatic cancer cells to natural killer cell-mediated lysis by upregulating MICA and MICB via the PI3K/Akt signaling pathway. BMC Cancer (2014) 0.90
Forkhead box protein C2 contributes to invasion and metastasis of extrahepatic cholangiocarcinoma, resulting in a poor prognosis. Cancer Sci (2013) 0.90
Forkhead box protein C2 contributes to invasion and metastasis of extrahepatic cholangiocarcinoma, resulting in a poor prognosis. Cancer Sci (2013) 0.90
An individual with gastric schwannoma with pathologically malignant potential surviving two years after laparoscopy-assisted partial gastrectomy. Case Rep Gastroenterol (2011) 0.90
Prognostic Role of Conversion Surgery for Unresectable Gastric Cancer. Ann Surg Oncol (2015) 0.88
HLA class I expression and its alteration by preoperative hyperthermo-chemoradiotherapy in patients with rectal cancer. PLoS One (2014) 0.78
Risk Factors for Recurrence After Curative Conversion Surgery for Unresectable Gastric Cancer. Anticancer Res (2015) 0.78
Blood group substances as potential therapeutic agents for the prevention and treatment of infection with noroviruses proving novel binding patterns in human tissues. PLoS One (2014) 0.78
Immunoglobulin G4-Related Retroperitoneal Fibrosis Treated with Hochuekkito, a Kampo Medicine, following Steroid Treatment. Case Rep Gastroenterol (2014) 0.75
Arteriovenous malformation detected by small bowel endoscopy. Case Rep Gastroenterol (2014) 0.75
Fucosylated Glycans in α1-Acid Glycoprotein for Monitoring Treatment Outcomes and Prognosis of Cancer Patients. PLoS One (2016) 0.75
Lung adenocarcinoma with anomalous bronchi and pulmonary veins preoperatively identified by computed tomography. Thorac Cancer (2016) 0.75
Efficacy of system l amino acid transporter 1 inhibition as a therapeutic target in esophageal squamous cell carcinoma. Cancer Sci (2016) 0.75
Low Expression of FBXO45 Is Associated with Gastric Cancer Progression and Poor Prognosis. Anticancer Res (2017) 0.75
Double Endoscopic Intraluminal Operation (DEILO) for Early Gastric Cancer: Outcome of Novel Procedure for Endoscopic Submucosal Dissection. Anticancer Res (2017) 0.75
Clinical Significance of Salvage Esophagectomy for Patients with Esophageal Cancer and Factors of Influencing Long-term Survival. Anticancer Res (2017) 0.75
Wide expression of ZEB1 in sarcomatous component of spindle cell carcinoma of the esophagus. Pathol Int (2015) 0.75
L-[3-¹⁸F]-α-methyltyrosine uptake by lymph node metastasis is a predictor of complete response to CRT in esophageal cancer. Anticancer Res (2014) 0.75