GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn's disease.

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Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation. Oncotarget (2017) 0.75

Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol (2009) 25.96

Genetics and pathogenesis of inflammatory bowel disease. Nature (2011) 7.79

Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol (2008) 5.86

Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity (2009) 5.43

GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis. N Engl J Med (2007) 4.94

Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J Exp Med (2012) 3.20

The biology of innate lymphoid cells. Nature (2015) 2.68

Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway. Gastroenterology (2008) 2.56

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation. Front Immunol (2014) 2.03

Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease. Gastroenterology (2011) 1.73

Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis. Immunity (2015) 1.66

Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology. Science (2015) 1.64

Innate lymphoid cells in the initiation, regulation and resolution of inflammation. Nat Med (2015) 1.63

Revisiting Crohn's disease as a primary immunodeficiency of macrophages. J Exp Med (2009) 1.54

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation. Gut (2013) 1.44

Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease. Gastroenterology (2008) 1.35

Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells. J Immunol (2007) 1.34

GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis. Int Immunol (2009) 1.21

Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell function. Clin Immunol (2009) 1.11

Advances in IBD genetics. Nat Rev Gastroenterol Hepatol (2014) 1.09

Acquisition of antigen-presenting functions by neutrophils isolated from mice with chronic colitis. J Immunol (2012) 1.06

The monocyte-macrophage axis in the intestine. Cell Immunol (2014) 0.97

Granulocyte-macrophage colony-stimulating factor autoantibodies: a marker of aggressive Crohn's disease. Inflamm Bowel Dis (2013) 0.96

Granulocyte macrophage colony-stimulating factor and the intestinal innate immune cell homeostasis in Crohn's disease. Am J Physiol Gastrointest Liver Physiol (2014) 0.95

Loss of GM-CSF signalling in non-haematopoietic cells increases NSAID ileal injury. Gut (2010) 0.91

The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD. Nat Rev Gastroenterol Hepatol (2015) 0.90

Granulocyte macrophage-colony-stimulating factor autoantibodies and increased intestinal permeability in Crohn disease. J Pediatr Gastroenterol Nutr (2011) 0.90

Sargramostim (GM-CSF) for induction of remission in Crohn's disease: a cochrane inflammatory bowel disease and functional bowel disorders systematic review of randomized trials. Inflamm Bowel Dis (2012) 0.88

Myeloid-derived suppressor cells in the inflammatory bowel diseases. Inflamm Bowel Dis (2013) 0.88

Peripheral monocyte functions and activation in patients with quiescent Crohn's disease. PLoS One (2013) 0.86

Granulocyte macrophage colony-stimulating factor auto-antibodies and disease relapse in inflammatory bowel disease. Am J Gastroenterol (2013) 0.86

Standardized serum GM-CSF autoantibody testing for the routine clinical diagnosis of autoimmune pulmonary alveolar proteinosis. J Immunol Methods (2013) 0.86

Reprogramming of monocytes by GM-CSF contributes to regulatory immune functions during intestinal inflammation. J Immunol (2015) 0.85

GM-CSF as a target in inflammatory/autoimmune disease: current evidence and future therapeutic potential. Expert Rev Clin Immunol (2015) 0.84

Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice. Inflamm Bowel Dis (2011) 0.82

Systematic review: new serological markers (anti-glycan, anti-GP2, anti-GM-CSF Ab) in the prediction of IBD patient outcomes. Autoimmun Rev (2014) 0.81

Granulocyte-macrophage colony stimulating factor and inflammatory bowel disease: establishing a connection. Gastroenterology (2011) 0.81

Immunoregulatory Role of Myeloid-derived Cells in Inflammatory Bowel Disease. Inflamm Bowel Dis (2015) 0.81

Increased prevalence of luminal narrowing and stricturing identified by enterography in pediatric Crohn's disease patients with elevated granulocyte-macrophage colony stimulating factor autoantibodies. Inflamm Bowel Dis (2013) 0.79

Paediatric Crohn disease patients with stricturing behaviour exhibit ileal granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibody production and reduced neutrophil bacterial killing and GM-CSF bioactivity. Clin Exp Immunol (2013) 0.77