Apparent underdiagnosis of Cerebrotendinous Xanthomatosis revealed by analysis of ~60,000 human exomes.

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Published in Mol Genet Metab on October 26, 2015

Authors

Vivek Appadurai1, Andrea DeBarber2, Pei-Wen Chiang2, Shailendra B Patel3, Robert D Steiner4, Charles Tyler5, Penelope E Bonnen6

Author Affiliations

1: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
2: Physiology & Pharmacology Department, Oregon Health & Science University, Portland, OR 97239, USA.
3: Division of Endocrinology, Diabetes and Metabolism, University of Cincinnati, ML 0547, 231 Albert Sabin Way, Cincinnati, OH 45219, USA.
4: Marshfield Clinic Research Foundation and University of Wisconsin, Marshfield and Madison, WI, USA.
5: Retrophin, New York, NY, USA.
6: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: pbonnen@bcm.edu.

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