Pharmacokinetics of felodipine after intravenous and chronic oral administration in patients with congestive heart failure.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 1379969)

Published in Br J Clin Pharmacol on July 01, 1989

Authors

P H Dunselman1, B Edgar, A H Scaf, C E Kuntze, H Wesseling

Author Affiliations

1: Department of Cardiology, Groningen University, The Netherlands.

Articles cited by this

Commentary: a physiological approach to hepatic drug clearance. Clin Pharmacol Ther (1975) 7.96

The first pass metabolism of nifedipine in man. Br J Clin Pharmacol (1984) 1.99

Pharmacokinetic and pharmacodynamic studies of felodipine in healthy subjects after various single, oral and intravenous doses. Biopharm Drug Dispos (1987) 1.70

Nifedipine increases and glyceryl trinitrate decreases apparent liver blood flow in normal subjects. Br J Clin Pharmacol (1984) 1.69

Vascular selectivity of felodipine. Drugs (1985) 1.62

Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man. Biochem Pharmacol (1984) 1.60

Pharmacokinetic parameter estimates from several least squares procedures: superiority of extended least squares. J Pharmacokinet Biopharm (1985) 1.36

Felodipine kinetics in healthy men. Clin Pharmacol Ther (1985) 1.35

The effect of nisoldipine on apparent liver blood flow and effective renal plasma flow. Br J Clin Pharmacol (1985) 1.20

Relationship between central hemodynamics and regional blood flow in normal subjects and in patients with congestive heart failure. Circulation (1984) 1.18

Treatment of essential hypertension with felodipine in combination with a diuretic. Eur J Clin Pharmacol (1986) 1.10

First-pass elimination. Basic concepts and clinical consequences. Clin Pharmacokinet (1984) 1.06

Extended least squares nonlinear regression: a possible solution to the "choice of weights" problem in analysis of individual pharmacokinetic data. J Pharmacokinet Biopharm (1984) 1.03

The trans-hepatic extraction of nifedipine. Br J Clin Pharmacol (1987) 0.98

Comparison of high-selectivity gas chromatographic methods, including column switching, for the determination of felodipine in plasma. J Chromatogr (1987) 0.96

Effects of single and repeated doses of the calcium antagonist felodipine on blood pressure, renal function, electrolytes and water balance, and renin-angiotensin-aldosterone system in hypertensive patients. J Cardiovasc Pharmacol (1987) 0.91

Efficacy of felodipine in chronic congestive heart failure: a placebo controlled haemodynamic study at rest and during exercise and orthostatic stress. Br Heart J (1987) 0.90

The contribution of nisoldipine-induced changes in liver blood flow to its pharmacokinetics after oral administration. Br J Clin Pharmacol (1989) 0.88

Pharmacokinetics and haemodynamic effects of felodipine as monotherapy in hypertensive patients. Clin Invest Med (1987) 0.85

Dynamic dialysis as a method for studying protein binding. I. Factors affecting the kinetics of dialysis through a cellophane membrane. J Pharm Sci (1970) 0.79

Articles by these authors

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region. Cell (1983) 6.01

Pharmacokinetic and pharmacodynamic studies of felodipine in healthy subjects after various single, oral and intravenous doses. Biopharm Drug Dispos (1987) 1.70

Late potentials in a bradycardia-dependent long QT syndrome associated with sudden death during sleep. J Am Coll Cardiol (1992) 1.64

Pharmacokinetics and pharmacodynamics of the enantiomers of warfarin in man. Clin Pharmacol Ther (1974) 1.61

Inhibition of dihydropyridine metabolism in rat and human liver microsomes by flavonoids found in grapefruit juice. J Pharmacol Exp Ther (1992) 1.52

Interaction of diphenylhydantoin (DPH) and tolbutamide in man. Eur J Clin Pharmacol (1975) 1.46

Repair of aortic coarctation in infants. J Thorac Cardiovasc Surg (1991) 1.44

Impact of clinical trials on the adoption of new drugs within a university hospital. Eur J Clin Pharmacol (1991) 1.42

Endothelium dependent relaxation in two different models of chronic heart failure and the effect of ibopamine. Cardiovasc Res (1993) 1.38

Clinical and neurohumoral differences between spirapril and captopril in mild to moderate chronic congestive heart failure. J Card Fail (1997) 1.38

Felodipine kinetics in healthy men. Clin Pharmacol Ther (1985) 1.35

Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects. Eur J Clin Pharmacol (1995) 1.34

Clinical pharmacology and primary health care in Europe--a gap to bridge. The WHO Working Group on Clinical Pharmacology in Europe. Eur J Clin Pharmacol (1990) 1.30

Ethanol enhances the hemodynamic effects of felodipine. Clin Invest Med (1989) 1.26

Towards understanding treatment preferences of hospital physicians. Soc Sci Med (1993) 1.22

Acute diuretic/natriuretic properties of felodipine in man. Drugs (1985) 1.20

Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans. Clin Pharmacol Ther (1991) 1.16

Sequences and studies of bacteriophage T4 rII mutants. J Mol Biol (1987) 1.15

Effects of grapefruit juice ingestion--pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men. Eur J Clin Pharmacol (1997) 1.12

Reduction of reperfusion arrhythmias in the ischemic isolated rat heart by angiotensin converting enzyme inhibitors: a comparison of captopril, enalapril, and HOE 498. J Cardiovasc Pharmacol (1986) 1.11

Drug use in pregnancy: a comparative appraisal of data collecting methods. Eur J Clin Pharmacol (1993) 1.06

The interaction effect of grapefruit juice is maximal after the first glass. Eur J Clin Pharmacol (1998) 1.02

Quality of life on antihypertensive therapy: a randomized double-blind controlled trial of captopril and atenolol. J Hypertens (1990) 1.01

Captopril reduces purine loss and reperfusion arrhythmias in the rat heart after coronary artery occlusion. Eur J Pharmacol (1984) 1.00

Does indirect consultation lead to overprescribing in general practice? Soc Sci Med (1987) 0.98

Inhibition of 17 beta-estradiol metabolism by grapefruit juice in ovariectomized women. Maturitas (1994) 0.97

4-Aminopyridine kinetics. Clin Pharmacol Ther (1982) 0.97

Effects of angiotensin II and captopril on inducible sustained ventricular tachycardia two weeks after myocardial infarction in the pig. J Cardiovasc Pharmacol (1989) 0.95

Value of New York Heart Association classification, radionuclide ventriculography, and cardiopulmonary exercise tests for selection of patients for congestive heart failure studies. Am Heart J (1988) 0.95

Suramin reverses non-depolarizing neuromuscular blockade in rat diaphragm. Eur J Pharmacol (1992) 0.94

In vivo effect of bradykinin during ischemia and reperfusion: improved electrical stability two weeks after myocardial infarction in the pig. J Cardiovasc Pharmacol (1991) 0.92

Rate-dependent effects of the class III antiarrhythmic drug almokalant on refractoriness in the pig. J Cardiovasc Pharmacol (1996) 0.92

Blood dyscrasias attributed to chloramphenicol. A review of 576 published and unpublished cases. Acta Med Scand (1972) 0.92

Grapefruit juice: a possible source of variability in blood concentration of cyclosporin A. Nephrol Dial Transplant (1993) 0.91

Pharmacokinetics of felodipine in patients with liver disease. Eur J Clin Pharmacol (1989) 0.91

Acute haemodynamic effects of felodipine and verapamil in man, singly and with metoprolol. Drugs (1985) 0.89

Selective and time related activation of the cardiac renin-angiotensin system after experimental heart failure: relation to ventricular function and morphology. Cardiovasc Res (1993) 0.88

Felodipine clinical pharmacokinetics. Clin Pharmacokinet (1991) 0.88

Absorption, distribution and elimination of felodipine in man. Drugs (1985) 0.88

Effects of 4-aminopyridine in elderly patients with Alzheimer's disease. N Engl J Med (1984) 0.87

Yohimbine pharmacokinetics and interaction with the sympathetic nervous system in normal volunteers. Eur J Clin Pharmacol (1992) 0.87

Once daily felodipine in patients with primary Raynaud's phenomenon. Eur J Clin Pharmacol (1991) 0.87

Acute effects of felodipine and nifedipine on hepatic and forearm blood flow in healthy men. Eur J Clin Pharmacol (1990) 0.86

Potentiation of isosorbide dinitrate-induced coronary dilatation by captopril. J Cardiovasc Pharmacol (1987) 0.86

Using inhibitors to study embryogenesis. Methods Cell Biol (1994) 0.86

Pharmacokinetics and blood pressure effects of felodipine in elderly hypertensive patients. A comparison with young healthy subjects. Clin Pharmacokinet (1988) 0.86

Drug expectations and drug choices of hospital physicians. J Intern Med (1993) 0.86

Concentration-dependent protection by captopril against myocardial damage during ischemia and reperfusion in a closed chest pig model. J Cardiovasc Pharmacol (1987) 0.85

Concentration-dependent protection by captopril against ischemia-reperfusion injury in the isolated rat heart. Arch Int Pharmacodyn Ther (1986) 0.84

Plasma levels of acetylsalicylic acid and salicylic acid after oral ingestion of plain and buffered acetylsalicylic acid in relation to bleeding time and thrombocyte function. Pharm Weekbl Sci (1983) 0.84

A preliminary investigation of the renal and hepatic excretion of gallamine triethiodide in man. Br J Anaesth (1978) 0.84

Inhibition of the transport of d-tubocurarine from blood to bile by k-strophantoside in the isolated perfused rat liver. Eur J Pharmacol (1968) 0.84

Effect of metoclopramide on dopamine-induced changes in renal function in healthy controls and in patients with renal disease. Clin Sci (Lond) (1988) 0.82

The effect of dantrolene sodium in relation to blood levels in spastic patients after prolonged administration. J Neurol Neurosurg Psychiatry (1981) 0.82

Sustained atrial flutter around the tricuspid valve in pigs: differentiation of procainamide (class IA) from flecainide (class IC) and their rate-dependent effects. J Cardiovasc Pharmacol (1993) 0.82

Effects of converting enzyme inhibitors on coronary flow and myocardial ischemia. J Cardiovasc Pharmacol (1992) 0.81

The relationship between disposition and duration of action of congeneric series of steroidal neuromuscular blocking agents. Acta Anaesthesiol Scand (1977) 0.81

Basic pharmacology of ACE-inhibitors with respect to ischaemic heart disease: prostaglandins and bradykinin. Eur Heart J (1990) 0.81

The effects of bradykinin and the ischemic isolated rat heart. Horm Metab Res Suppl (1990) 0.81

The effects of oral pretreatment with zofenopril, an angiotensin-converting enzyme inhibitor, on early reperfusion and subsequent electrophysiologic stability in the pig. Cardiovasc Drugs Ther (1990) 0.81

Low-dose bromocriptine therapy in Parkinson's disease: double-blind, placebo-controlled study. Neurology (1986) 0.81

Relationship between plasma concentration and effect of dantrolene sodium in man. Eur J Clin Pharmacol (1979) 0.81

A double-blind controlled trial of low dose acetylsalicylic acid and dipyridamole in the treatment of Raynaud's phenomenon. Vasa Suppl (1987) 0.81

A population study of the pharmacokinetics of felodipine. Br J Clin Pharmacol (1991) 0.81

The haemodynamic effects of two angiotensin converting enzyme inhibitors, enalaprilat and zofenoprilat, in the rat: evidence for the involvement of bradykinin. J Hypertens Suppl (1989) 0.80

Effects of acetylsalicylic acid on peripheral hemodynamics in patients with chronic heart failure treated with angiotensin-converting enzyme inhibitors. J Cardiovasc Pharmacol (1994) 0.80

Effects of atenolol, labetalol and propranolol on the peripheral circulation in hypertensive patients without obstructive vascular disease. Eur J Clin Pharmacol (1985) 0.80

Efficacy of felodipine in congestive heart failure. Eur Heart J (1989) 0.80

Plasma concentration-effect relationship of felodipine intravenously in patients with congestive heart failure. J Cardiovasc Pharmacol (1989) 0.80

Digoxin-felodipine interaction in patients with congestive heart failure. Eur J Clin Pharmacol (1988) 0.80

Investigating drug use in pregnancy. Methodological problems and perspectives. Pharm Weekbl Sci (1991) 0.80

Strand break repair, DNA polymerase activity and heat radiosensitization in thermotolerant cells. Int J Hyperthermia (1986) 0.80

The lower third molar and antiphlogistics. Int J Oral Surg (1982) 0.79

Sustained protection by iloprost of the porcine heart in the acute and chronic phases of myocardial infarction. J Cardiovasc Pharmacol (1985) 0.79

Beneficial effects of bradykinin on porcine ischemic myocardium. Basic Res Cardiol (1991) 0.79

Converting enzyme inhibitors and the role of the sulfhydryl group in the potentiation of exo- and endogenous nitrovasodilators. J Cardiovasc Pharmacol (1991) 0.79

Captopril-induced increase in coronary flow: an SH-dependent effect on arachidonic acid metabolism? J Cardiovasc Pharmacol (1987) 0.79

Pharmacokinetics and hemodynamic and diuretic/natriuretic effects of felodipine administered as an extended-release tablet. Cardiovasc Drugs Ther (1990) 0.79

Blood dyscrasias attributed to chloramphenicol: a review of 641 published and unpublished cases. Postgrad Med J (1974) 0.79

Prescribing pattern in a Dutch university hospital. J Clin Pharm Ther (1991) 0.79

Communicating a drug alert. A case study on acitretin in The Netherlands. Eur J Clin Pharmacol (1994) 0.78

Uptake and excretion of vecuronium bromide and pancuronium bromide in the isolated perfused rat liver. Anesthesiology (1988) 0.78

Hemodynamic effects of high dosages of verapamil and the lack of protection by 4-aminopyridine in the rabbit. Arch Int Pharmacodyn Ther (1983) 0.78

Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17 beta-estradiol. Eur J Drug Metab Pharmacokinet (1996) 0.78

Dose-dependent effects of felodipine on diuresis and natriuresis in healthy subjects. J Cardiovasc Pharmacol (1988) 0.78

The influence of infusion rate on the hemodynamic effects of felodipine. Clin Pharmacol Ther (1990) 0.78

Differences in vasomotor control between human gastroepiploic and left internal mammary artery. Circulation (1992) 0.78

Effects of intravenously administered isoxsuprine in patients with Raynaud's phenomenon. Vasa (1975) 0.78

Effects of diltiazem on reperfusion-induced arrhythmias in vitro and in vivo. J Mol Cell Cardiol (1986) 0.78

Protective effects of captopril against ischemia/reperfusion-induced ventricular arrhythmias in vitro and in vivo. Am J Med (1988) 0.78

Comparative pharmacokinetics of d-tubocurarine and metocurine in man. Anesthesiology (1979) 0.77