Published in Aging Cell on January 21, 2016
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity (1995) 10.59
Prestin is the motor protein of cochlear outer hair cells. Nature (2000) 7.41
Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced hearing loss. J Neurosci (2009) 6.20
Programmed cell death induced by ceramide. Science (1993) 5.43
TNF-mediated inflammatory disease. J Pathol (2008) 5.00
Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon. Nature (1986) 4.98
Minireview: the OPG/RANKL/RANK system. Endocrinology (2001) 4.47
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet (1997) 4.46
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem (1998) 3.88
Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ (2003) 3.66
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity (1997) 3.11
Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL. Neuron (2005) 2.01
Distinct signaling pathways in TRAIL- versus tumor necrosis factor-induced apoptosis. Mol Cell Biol (2006) 1.88
Prospective evaluation of hearing impairment as a sequela of acute bacterial meningitis. N Engl J Med (1984) 1.69
Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis. J Cell Biol (2000) 1.43
The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Ann Rheum Dis (1999) 1.38
Proinflammatory cytokines expression in noise-induced damaged cochlea. J Neurosci Res (2006) 1.36
Three is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling. Cytokine (2007) 1.28
Immune-mediated inner ear disease. Acta Otolaryngol (2006) 1.23
Corticosteroids for acute bacterial meningitis. Cochrane Database Syst Rev (2013) 1.22
Sudden sensorineural hearing loss: an autoimmune disease? Autoimmun Rev (2011) 1.17
A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss. Am J Hum Genet (2010) 1.11
Caspase-8 regulation of TRAIL-mediated cell death. Exp Oncol (2012) 1.11
Relation of concentrations of Haemophilus influenzae type b in cerebrospinal fluid to late sequelae of patients with meningitis. J Pediatr (1982) 1.09
GATA3 and NeuroD distinguish auditory and vestibular neurons during development of the mammalian inner ear. Mech Dev (2004) 1.08
Osteoprotegrin knockout mice demonstrate abnormal remodeling of the otic capsule and progressive hearing loss. Laryngoscope (2006) 1.08
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) signaling and cell death in the immature central nervous system after hypoxia-ischemia and inflammation. J Biol Chem (2014) 1.02
Blocking TRAIL-DR5 signaling with soluble DR5 reduces delayed neuronal damage after transient global cerebral ischemia. Neurobiol Dis (2010) 1.00
Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes. Neuroscience (2008) 0.99
Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions. Cell Signal (2011) 0.93
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in central nervous system inflammation. J Mol Med (Berl) (2009) 0.90
Autoimmune inner ear disease: therapy. Am J Otol (1989) 0.90
Expression of TRAIL receptors in human autoreactive and foreign antigen-specific T cells. Cell Death Differ (2000) 0.86
Blockade of the tumor necrosis factor-related apoptosis inducing ligand death receptor DR5 prevents beta-amyloid neurotoxicity. Neuropsychopharmacology (2006) 0.85
Murine CMV-induced hearing loss is associated with inner ear inflammation and loss of spiral ganglia neurons. PLoS Pathog (2015) 0.84
Blood levels of TNF-α, IL-10, and IL-12 in idiopathic sudden sensorineural hearing loss. Laryngoscope (2013) 0.83
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kappaB-dependent maturation of normal and leukemic myeloid cells. J Leukoc Biol (2003) 0.83
Diagnostic and prognostic utility of measuring tumor necrosis factor in the peripheral circulation of patients with immune-mediated sensorineural hearing loss. Arch Otolaryngol Head Neck Surg (2012) 0.83
Inflammatory and immune responses in the cochlea: potential therapeutic targets for sensorineural hearing loss. Front Pharmacol (2014) 0.83
Loss of osteoprotegerin expression in the inner ear causes degeneration of the cochlear nerve and sensorineural hearing loss. Neurobiol Dis (2013) 0.82
Nitric oxide mediates TNF-α-induced apoptosis in the auditory cell line. Laryngoscope (2012) 0.81
Up-regulation of the DR5 expression by proteasome inhibitor MG132 augments TRAIL-induced apoptosis in soft tissue sarcoma cell lines. Cancer Res Treat (2011) 0.80
Death receptor 5 and neuroproliferation. Cell Mol Neurobiol (2011) 0.79
Mining immune epitopes in the inner ear. Otolaryngol Head Neck Surg (2013) 0.77