PubRank

J P Lecocq

Author PubWeight™ 110.85‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation. Nature 1992 5.45
2 HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product. Nature 1987 5.45
3 Chromogenic identification of genetic regulatory signals in Bacillus subtilis based on expression of a cloned Pseudomonas gene. Proc Natl Acad Sci U S A 1983 5.33
4 New versatile cloning and sequencing vectors based on bacteriophage M13. Gene 1983 4.55
5 Expression of rabies virus glycoprotein from a recombinant vaccinia virus. Nature 1984 3.32
6 Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene. Proc Natl Acad Sci U S A 1984 2.85
7 cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization. FEBS Lett 1991 2.70
8 Large-scale eradication of rabies using recombinant vaccinia-rabies vaccine. Nature 1992 2.67
9 Linker tailing: unphosphorylated linker oligonucleotides for joining DNA termini. DNA 1984 2.56
10 Isolation of a human anti-haemophilic factor IX cDNA clone using a unique 52-base synthetic oligonucleotide probe deduced from the amino acid sequence of bovine factor IX. Nucleic Acids Res 1983 2.56
11 Regional localization on the human X chromosome and polymorphism of the coagulation factor IX gene (hemophilia B locus). Proc Natl Acad Sci U S A 1984 2.23
12 Carrier detection of Hemophilia B by using a restriction site polymorphism associated with the coagulation Factor IX gene. J Clin Invest 1984 2.07
13 Cell-free synthesis of enterotoxin of E. coli from a cloned gene. Nature 1980 2.02
14 Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis. Mol Biol Cell 1992 1.81
15 Molecular characterization of a 23-kilodalton major antigen secreted by Toxoplasma gondii. Proc Natl Acad Sci U S A 1989 1.73
16 A specific inhibitor of cysteine proteases impairs a Vif-dependent modification of human immunodeficiency virus type 1 Env protein. J Virol 1991 1.72
17 The cystic fibrosis gene has a "housekeeping"-type promoter and is expressed at low levels in cells of epithelial origin. J Biol Chem 1991 1.70
18 High-level production of biologically active human alpha 1-antitrypsin in Escherichia coli. Proc Natl Acad Sci U S A 1984 1.65
19 Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells. Proc Natl Acad Sci U S A 1992 1.62
20 The glutathione transferase activity and tissue distribution of a cloned Mr28K protective antigen of Schistosoma mansoni. EMBO J 1988 1.55
21 Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin. Nucleic Acids Res 1991 1.52
22 Molecular cloning of a protective antigen of schistosomes. Nature 1987 1.49
23 Oral vaccination of the fox against rabies using a live recombinant vaccinia virus. Nature 1986 1.45
24 The structural gene for the ribosomal protein S18 in Escherichia coli. I. Genetic studies on a mutant having an alteration in the protein S18. J Mol Biol 1973 1.44
25 Synthesis in E. coli of alpha 1-antitrypsin variants of therapeutic potential for emphysema and thrombosis. Nature 1985 1.44
26 Protection of mice from fatal measles encephalitis by vaccination with vaccinia virus recombinants encoding either the hemagglutinin or the fusion protein. Proc Natl Acad Sci U S A 1988 1.43
27 Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium. EMBO J 1991 1.40
28 Silica gel: an improved support for the solid-phase phosphotriester synthesis of oligonucleotides. Nucleic Acids Res 1982 1.40
29 Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer. J Clin Invest 1993 1.35
30 A conditionally lethal mutation of Escherichia coli affecting the gene coding for ribosomal protein S2 (rpsB). J Mol Biol 1979 1.24
31 The influence of mRNA primary and secondary structure on human IFN-gamma gene expression in E. coli. Nucleic Acids Res 1984 1.21
32 Prokaryotic histone-like protein interacting with RNA polymerase. Proc Natl Acad Sci U S A 1980 1.21
33 Cloning and expression of a cDNA coding for the anticoagulant hirudin from the bloodsucking leech, Hirudo medicinalis. Proc Natl Acad Sci U S A 1986 1.20
34 The firA gene, a locus involved in the expression of rifampicin resistance in Escherichia coli. I. Characterisation of lambdafirA transducing phages constructed in vitro. Mol Gen Genet 1977 1.13
35 Protective immunity induced in rat schistosomiasis by a single dose of the Sm28GST recombinant antigen: effector mechanisms involving IgE and IgA antibodies. Eur J Immunol 1993 1.09
36 Isotypic restriction of the antibody response to human immunodeficiency virus. AIDS Res Hum Retroviruses 1988 1.07
37 Use of recombinant vaccinia-rabies virus for oral vaccination of fox cubs (Vulpes vulpes, L) against rabies. Vet Microbiol 1988 1.07
38 HIV-1 core proteins expressed from recombinant vaccinia viruses. AIDS Res Hum Retroviruses 1989 1.06
39 Characterisation of two differently processed forms of human recombinant factor IX synthesised in CHO cells transformed with a polycistronic vector. Eur J Biochem 1988 1.05
40 The firA gene, a locus involved in the expression of rifampicin resistance in Escherichia coli. II. Characterisation of bacterial proteins coded by lambdafirA transducing phages. Mol Gen Genet 1977 1.02
41 Inter-species variation of schistosome 28-kDa glutathione S-transferases. Mol Biochem Parasitol 1992 1.01
42 Use of recombinant vaccinia-rabies glycoprotein virus for oral vaccination of wildlife against rabies: innocuity to several non-target bait consuming species. J Wildl Dis 1989 1.00
43 DNA binding factors that bind to the negative regulatory element of the human immunodeficiency virus-1: regulation by nef. J Acquir Immune Defic Syndr 1990 0.98
44 Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer. Nucleic Acids Res 1992 0.97
45 Similar genetic organization between a region of fowlpox virus DNA and the vaccinia virus HindIII J fragment despite divergent location of the thymidine kinase gene. Virology 1987 0.95
46 Active gamma-carboxylated human factor IX expressed using recombinant DNA techniques. Nature 1985 0.95
47 Sensitivity of bacteriophage Mu-1 development to rifampicin and streptolydigin. Mol Gen Genet 1974 0.92
48 Fowlpox virus recombinant encoding the measles virus fusion protein: protection of mice against fatal measles encephalitis. Vaccine 1990 0.92
49 Vaccinia recombinants expressing early bovine papilloma virus (BPV1) proteins: retardation of BPV1 tumour development. Vaccine 1990 0.91
50 Vaccination of goats against the trematode Schistosoma bovis with a recombinant homologous schistosome-derived glutathione S-transferase. Parasite Immunol 1994 0.89
51 Construction of fowlpox virus vectors with intergenic insertions: expression of the beta-galactosidase gene and the measles virus fusion gene. J Virol 1990 0.89
52 Crystallization and preliminary X-ray diffraction studies of a protective cloned 28 kDa glutathione S-transferase from Schistosoma mansoni. J Mol Biol 1992 0.89
53 Cell-mediated immune proliferative responses to HIV-1 of chimpanzees vaccinated with different vaccinia recombinant viruses. AIDS Res Hum Retroviruses 1989 0.88
54 Immunological crossreactivity between the human immunodeficiency virus type 1 virion infectivity factor and a 170-kD surface antigen of Schistosoma mansoni. J Exp Med 1990 0.88
55 Plasmid transduction in Streptococcus thermophilus. Mol Gen Genet 1988 0.87
56 Evaluation of recombinant DNA-directed E.coli produced alpha 1-antitrypsin as an anti-neutrophil elastase for potential use as replacement therapy of alpha 1-antitrypsin deficiency. Biochem Biophys Res Commun 1985 0.87
57 Molecular cloning and tissue distribution of a 26-kilodalton Schistosoma mansoni glutathione S-transferase. Mol Biochem Parasitol 1990 0.87
58 First field trial of fox vaccination against rabies using a vaccinia-rabies recombinant virus. Vet Rec 1988 0.86
59 Isolation of recombinant partial gag gene product p18 (HIV-1Bru) from Escherichia coli. J Chromatogr 1989 0.86
60 Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations. Mol Cell Biol 1992 0.86
61 M13 bacteriophage vectors for the expression of foreign proteins in Escherichia coli: the rabies glycoprotein. J Mol Appl Genet 1984 0.83
62 Polarity of secretion of alpha 1-antitrypsin by human respiratory epithelial cells after adenoviral transfer of a human alpha 1-antitrypsin cDNA. Am J Respir Cell Mol Biol 1995 0.82
63 Low-conductance chloride channels in IEC-6 and CF nasal cells expressing CFTR. Am J Physiol 1993 0.82
64 Fusion of restriction termini using synthetic adaptor oligonucleotides. Gene 1982 0.82
65 Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C. J Biol Chem 1992 0.82
66 Determination of B-cell epitopes of nef HIV-I protein: immunogenicity related to their structure. Mol Immunol 1992 0.79
67 Two independent domains of factor VIII co-expressed using recombinant vaccinia viruses have procoagulant activity. Biochem Biophys Res Commun 1987 0.78
68 Use of vaccinia rabies recombinant for oral vaccination of wildlife. Vet Microbiol 1990 0.78
69 Increased biological activity of a recombinant factor IX variant carrying alanine at position +1. Protein Eng 1990 0.78
70 Development of animal recombinant DNA vaccine and its efficacy in foxes. Rev Infect Dis 1989 0.77
71 Nomenclature and location of bacterial mutations modifying the frequency of lysogenization of E. coli by lambdoid phages. Mol Gen Genet 1976 0.77
72 GP38, P28-I and P28-II: candidates for a vaccine against schistosomiasis. Mem Inst Oswaldo Cruz 1987 0.76
73 Evidence for extended maintenance of the corpus luteum by uterine infusion of a recombinant trophoblast alpha-interferon (trophoblastin) in sheep. J Endocrinol 1990 0.76
74 HIV-specific T lymphocyte immunity in mice immunized with a recombinant vaccinia virus. Eur J Immunol 1988 0.76
75 Recombinant polyoma--vaccinia viruses: T antigen expression vectors and anti-tumor immunization agents. Biochimie 1988 0.76
76 T helper cell epitopes of the human immunodeficiency virus (HIV-1) nef protein in rats and chimpanzees. Mol Immunol 1992 0.76
77 Overproduction of a viral protein during infection of a lyc mutant of Escherichia coli with phage lambdamm434. Virology 1977 0.75
78 [Isolation and characterization of a strain of E. coli K12 with a mutation affecting the transcription]. Rev Latinoam Microbiol 1975 0.75
79 [Genetic and functional characterization of mutants of the lambda phage affected in the regulation of lysogenization]. Rev Latinoam Microbiol 1977 0.75
80 [A bacterial mutation augmenting the frequency of lysogenation by lambda phage]. Arch Int Physiol Biochim 1973 0.75
81 Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene. 1984. Biotechnology 1992 0.75
82 [The impact of genetic engineering in hemorrhagic and thrombotic diseases]. Rev Med Brux 1987 0.75
83 [Effects of a mutation affecting the beta subunit of RNA polymerase of Escherichia coli on the behavior of lambda bacteriophage]. Arch Int Physiol Biochim 1973 0.75
84 [Study of bacterial and viral recombination functions interchangeability]. Ann Inst Pasteur (Paris) 1970 0.75
85 [Genetic and biochemical aspects of transcription regulation in the bacteria E. coli and its phages]. Biochimie 1973 0.75
86 [Recent applications of genetic engineering in the field of vaccines and blood factors]. Rev Med Brux 1986 0.75
87 [Mutations of lambda phage increasing the frequency of lysogenization (proceedings)]. Arch Int Physiol Biochim 1976 0.75
88 Protective antigens in experimental schistosomiasis. Acta Trop Suppl 1987 0.75