Immunogenicity of Therapeutic Protein Aggregates.

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🔗 View Article (PMID 26869409)

Published in J Pharm Sci on February 01, 2016

Authors

Ehab M Moussa1, Jainik P Panchal1, Balakrishnan S Moorthy1, Janice S Blum2, Marisa K Joubert3, Linda O Narhi3, Elizabeth M Topp4

Author Affiliations

1: Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907.
2: Department of Microbiology and Immunology, School of Medicine, Indiana University, Indianapolis, Indiana 46202.
3: Amgen Inc., Process Development, Thousand Oaks, California 91320.
4: Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907. Electronic address: topp@purdue.edu.

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Mouse Models for Assessing Protein Immunogenicity: Lessons and Challenges. J Pharm Sci (2016) 0.76