Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein.

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Published in Cell Rep on March 10, 2016

Authors

Anna-Janina Behrens1, Snezana Vasiljevic1, Laura K Pritchard1, David J Harvey1, Rajinder S Andev2, Stefanie A Krumm2, Weston B Struwe1, Albert Cupo3, Abhinav Kumar1, Nicole Zitzmann1, Gemma E Seabright1, Holger B Kramer4, Daniel I R Spencer5, Louise Royle5, Jeong Hyun Lee6, Per J Klasse3, Dennis R Burton7, Ian A Wilson8, Andrew B Ward6, Rogier W Sanders9, John P Moore3, Katie J Doores10, Max Crispin11

Author Affiliations

1: Oxford Glycobiology Institute and Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
2: Department of Infectious Diseases, Faculty of Life Sciences and Medicine, King's College London, Guy's Hospital, London SE1 9RT, UK.
3: Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10021, USA.
4: Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.
5: Ludger, Ltd., Culham Science Centre, Abingdon, Oxfordshire OX14 3EB, UK.
6: Department of Integrative Structural and Computational Biology, International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center and CAVD, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
7: Department of Immunology and Microbial Science, IAVI Neutralizing Antibody Center and CAVD, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, the Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, MA 02142, USA.
8: Department of Integrative Structural and Computational Biology, International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center and CAVD, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
9: Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10021, USA; Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center of the University of Amsterdam, 1105 AZ Amsterdam, the Netherlands.
10: Department of Infectious Diseases, Faculty of Life Sciences and Medicine, King's College London, Guy's Hospital, London SE1 9RT, UK. Electronic address: katie.doores@kcl.ac.uk.
11: Oxford Glycobiology Institute and Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK. Electronic address: max.crispin@bioch.ox.ac.uk.

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