Activation of AMPK Prevents Monocrotaline-Induced Extracellular Matrix Remodeling of Pulmonary Artery.

Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res (2006) 8.26

Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol (2004) 5.79

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. Genes Dev (2011) 5.26

Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2007) 2.46

A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy. Am J Physiol Renal Physiol (2006) 2.05

Smooth muscle cell matrix metalloproteinases in idiopathic pulmonary arterial hypertension. Eur Respir J (2005) 1.98

Primary pulmonary hypertension: a vascular biology and translational research "Work in progress". Circulation (2000) 1.97

AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function. J Clin Invest (2013) 1.84

Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease. J Clin Invest (2000) 1.74

Induction of AMPK activity corrects early pathophysiological alterations in the subtotal nephrectomy model of chronic kidney disease. Am J Physiol Renal Physiol (2013) 1.63

Reversible or irreversible remodeling in pulmonary arterial hypertension. Am J Respir Cell Mol Biol (2009) 1.33

The extracellular matrix of blood vessels. Curr Pharm Des (2009) 1.18

Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling. Am J Physiol Heart Circ Physiol (2011) 1.14

Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension. Circulation (2013) 1.11

AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease. J Intern Med (2014) 1.08

Metformin action: concentrations matter. Cell Metab (2015) 1.01

Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension. Br J Pharmacol (2009) 1.01

Effect of metformin on the proliferation, migration, and MMP-2 and -9 expression of human umbilical vein endothelial cells. Mol Med Rep (2012) 0.98

AMP-activated protein kinase suppresses matrix metalloproteinase-9 expression in mouse embryonic fibroblasts. J Biol Chem (2011) 0.97

Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats. Acta Pharmacol Sin (2011) 0.92

Matrix metalloproteinases and their inhibitors in pulmonary hypertension. Eur Respir J (2012) 0.89

Age-related macular degeneration and changes in the extracellular matrix. Med Sci Monit (2014) 0.88

Deciphering the "matrix" in pulmonary vascular remodelling. Eur Respir J (2005) 0.87

Identification of new prognostic factors of pulmonary hypertension. Circ J (2010) 0.86

Protective action of hepatocyte growth factor on transforming growth factor beta-1-induced alpha-smooth muscle actin and extracellular matrix in cultured human peritoneal fibroblasts. Med Sci Monit (2010) 0.86

Adaptation and remodelling of the pulmonary circulation in pulmonary hypertension. Can J Cardiol (2014) 0.85

AMPK-dependent signaling modulates the suppression of invasion and migration by fenofibrate in CAL 27 oral cancer cells through NF-κB pathway. Environ Toxicol (2014) 0.83

Activation of AMPK inhibits pulmonary arterial smooth muscle cells proliferation. Exp Lung Res (2014) 0.83

Metformin rescues the MG63 osteoblasts against the effect of high glucose on proliferation. J Diabetes Res (2014) 0.83

Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2006) 0.83

Animal models of pulmonary hypertension: Rho kinase inhibition. Prog Biophys Mol Biol (2012) 0.82

Influence of ranibizumab treatment on the extracellular matrix in patients with neovascular age-related macular degeneration. Med Sci Monit (2014) 0.82

Effects of angiotensin II intervention on MMP-2, MMP-9, TIMP-1, and collagen expression in rats with pulmonary hypertension. Genet Mol Res (2015) 0.80

Extracellular matrix in deoxycholic acid decellularized aortic heart valves. Med Sci Monit (2012) 0.79

Adiponectin attenuates Ang Ⅱ-induced TGFβ1 production in human mesangial cells via an AMPK-dependent pathway. Biotechnol Appl Biochem (2015) 0.79

Inactivation of AMPK mediates high phosphate-induced extracellular matrix accumulation via NOX4/TGFß-1 signaling in human mesangial cells. Cell Physiol Biochem (2014) 0.79

Inhibition of Notch3 prevents monocrotaline-induced pulmonary arterial hypertension. Exp Lung Res (2015) 0.78

Association of TLR4 (896A/G and 1196C/T) Gene Polymorphisms with Asthma Risk: A Meta-Analysis. Med Sci Monit (2015) 0.76