Optimal Cutoff and Accuracy of an IgM Enzyme-Linked Immunosorbent Assay for Diagnosis of Acute Scrub Typhus in Northern Thailand: an Alternative Reference Method to the IgM Immunofluorescence Assay.

PubWeight™: 0.83‹?›

🔗 View Article (PMID 27008880)

Published in J Clin Microbiol on March 23, 2016

Authors

Stuart D Blacksell1, Cherry Lim2, Ampai Tanganuchitcharnchai2, Suthatip Jintaworn2, Pacharee Kantipong3, Allen L Richards4, Daniel H Paris5, Direk Limmathurotsakul6, Nicholas P J Day1

Author Affiliations

1: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
2: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
3: Chiangrai Prachanukhru Hospital, Chiangrai, Thailand.
4: Viral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, Maryland, USA Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
5: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, OX3 7FZ, United Kingdom; parigi@tropmedres.ac.
6: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand direk@tropmedres.ac.

Associated clinical trials:

Rickettsiae in Myanmar (Rickettsiae) | NCT03847870

Articles cited by this

Bayesian estimation of disease prevalence and the parameters of diagnostic tests in the absence of a gold standard. Am J Epidemiol (1995) 3.39

Scrub typhus serologic testing with the indirect immunofluorescence method as a diagnostic gold standard: a lack of consensus leads to a lot of confusion. Clin Infect Dis (2007) 3.23

Causes of non-malarial fever in Laos: a prospective study. Lancet Glob Health (2013) 3.20

Diagnosis of scrub typhus. Am J Trop Med Hyg (2010) 3.13

Bayesian approaches to modeling the conditional dependence between multiple diagnostic tests. Biometrics (2001) 2.72

Diagnostic test accuracy may vary with prevalence: implications for evidence-based diagnosis. J Clin Epidemiol (2008) 2.50

Comparative evaluation of selected diagnostic assays for the detection of IgG and IgM antibody to Orientia tsutsugamushi in Thailand. Am J Trop Med Hyg (2002) 2.18

Patient and sample-related factors that effect the success of in vitro isolation of Orientia tsutsugamushi. Southeast Asian J Trop Med Public Health (2007) 2.02

Orientia, rickettsia, and leptospira pathogens as causes of CNS infections in Laos: a prospective study. Lancet Glob Health (2015) 1.78

Genetic typing of the 56-kDa type-specific antigen gene of contemporary Orientia tsutsugamushi isolates causing human scrub typhus at two sites in north-eastern and western Thailand. FEMS Immunol Med Microbiol (2008) 1.65

Unresolved problems related to scrub typhus: a seriously neglected life-threatening disease. Am J Trop Med Hyg (2013) 1.64

Rapid diagnosis of scrub typhus in rural Thailand using polymerase chain reaction. Am J Trop Med Hyg (2006) 1.63

A highly sensitive quantitative real-time PCR assay based on the groEL gene of contemporary Thai strains of Orientia tsutsugamushi. Clin Microbiol Infect (2009) 1.52

Nonparametric estimation of ROC curves in the absence of a gold standard. Biometrics (2005) 1.40

Diagnostic accuracy of a loop-mediated isothermal PCR assay for detection of Orientia tsutsugamushi during acute Scrub Typhus infection. PLoS Negl Trop Dis (2011) 1.38

Detection of new genotypes of Orientia tsutsugamushi infecting humans in Thailand. Clin Microbiol Infect (2007) 1.26

Real-time multiplex PCR assay for detection and differentiation of rickettsiae and orientiae. Trans R Soc Trop Med Hyg (2008) 1.25

Maximum-likelihood estimation of sensitivity and specificity of ELISAs and faecal culture for diagnosis of paratuberculosis. Prev Vet Med (2002) 1.22

How to Determine the Accuracy of an Alternative Diagnostic Test when It Is Actually Better than the Reference Tests: A Re-Evaluation of Diagnostic Tests for Scrub Typhus Using Bayesian LCMs. PLoS One (2015) 1.20

Genotype diversity and distribution of Orientia tsutsugamushi causing scrub typhus in Thailand. J Clin Microbiol (2011) 1.04

Evaluation of an enzyme-linked immunosorbent assay in Thai scrub typhus patients. Am J Trop Med Hyg (1997) 1.04

Enzyme-linked immunosorbent assay for the diagnosis of melioidosis: better than we thought. Clin Infect Dis (2011) 1.01

Physiogeographic distribution of scrub typhus in Thailand. Acta Med Biol (Niigata) (1967) 0.98

Inter- and intra-operator variability in the reading of indirect immunofluorescence assays for the serological diagnosis of scrub typhus and murine typhus. Am J Trop Med Hyg (2013) 0.98

Analysis of the cross-reactivity of various 56 kDa recombinant protein antigens with serum samples collected after Orientia tsutsugamushi infection by ELISA. Am J Trop Med Hyg (2011) 0.98

Strategies for detecting rickettsiae and diagnosing rickettsial diseases. Future Microbiol (2015) 0.96

Pregnancy outcome in relation to treatment of murine typhus and scrub typhus infection: a fever cohort and a case series analysis. PLoS Negl Trop Dis (2014) 0.95

Isolation and characterization of Orientia tsutsugamushi from rodents captured following a scrub typhus outbreak at a military training base, Bothong district, Chonburi province, central Thailand. Am J Trop Med Hyg (2011) 0.94

Optimal Cutoff Titers for Indirect Immunofluorescence Assay for Diagnosis of Scrub Typhus. J Clin Microbiol (2015) 0.93

A nonhuman primate scrub typhus model: protective immune responses induced by pKarp47 DNA vaccination in cynomolgus macaques. J Immunol (2015) 0.90

Short report: variation in the 56-kD type-specific antigen gene of Orientia tsutsugamushi isolated from patients in Thailand. Am J Trop Med Hyg (2003) 0.89

Surveys of rodent-borne disease in Thailand with a focus on scrub typhus assessment. Integr Zool (2008) 0.85

Scrub typhus outbreak, northern Thailand, 2006-2007. Emerg Infect Dis (2013) 0.83

Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect. PLoS One (2013) 0.83

Occurrence of Orientia tsutsugamushi in small mammals from Thailand. Am J Trop Med Hyg (2003) 0.82

First report of an Orientia tsutsugamushi type TA716-related scrub typhus infection in Thailand. Vector Borne Zoonotic Dis (2010) 0.80

Dot-ELISA Rapid Test Using Recombinant 56-kDa Protein Antigens for Serodiagnosis of Scrub Typhus. Am J Trop Med Hyg (2015) 0.79

Articles by these authors

How to Determine the Accuracy of an Alternative Diagnostic Test when It Is Actually Better than the Reference Tests: A Re-Evaluation of Diagnostic Tests for Scrub Typhus Using Bayesian LCMs. PLoS One (2015) 1.20

Diagnostic Accuracy of the InBios Scrub Typhus Detect Enzyme-Linked Immunoassay for the Detection of IgM Antibodies in Northern Thailand. Clin Vaccine Immunol (2015) 1.09

Comparative Accuracy of the InBios Scrub Typhus Detect IgM Rapid Test for the Detection of IgM Antibodies by Using Conventional Serology. Clin Vaccine Immunol (2015) 1.00

Maintenance of leptospira species in leptospira Vanaporn Wuthiekanun agar. J Clin Microbiol (2014) 0.98

Optimal Cutoff Titers for Indirect Immunofluorescence Assay for Diagnosis of Scrub Typhus. J Clin Microbiol (2015) 0.93

A nonhuman primate scrub typhus model: protective immune responses induced by pKarp47 DNA vaccination in cynomolgus macaques. J Immunol (2015) 0.90

Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect. PLoS One (2013) 0.83

Soil Nutrient Depletion Is Associated with the Presence of Burkholderia pseudomallei. Appl Environ Microbiol (2016) 0.77

Antigenic Relationships among Human Pathogenic Orientia tsutsugamushi Isolates from Thailand. PLoS Negl Trop Dis (2016) 0.77

Utility of a Lateral Flow Immunoassay (LFI) to Detect Burkholderia pseudomallei in Soil Samples. PLoS Negl Trop Dis (2016) 0.75

Strong interferon-gamma mediated cellular immunity to scrub typhus demonstrated using a novel whole cell antigen ELISpot assay in rhesus macaques and humans. PLoS Negl Trop Dis (2017) 0.75

Estimating the burden of scrub typhus: A systematic review. PLoS Negl Trop Dis (2017) 0.75