Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation.

Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose. Front Pharmacol (2017) 0.76

CLOCK Promotes Endothelial Damage by Inducing Autophagy through Reactive Oxygen Species. Oxid Med Cell Longev (2016) 0.75

The Transcription Factor Bach1 Suppresses the Developmental Angiogenesis of Zebrafish. Oxid Med Cell Longev (2017) 0.75

Cell death: critical control points. Cell (2004) 22.56

The pathophysiology of mitochondrial cell death. Science (2004) 13.87

Heme oxygenase-1: unleashing the protective properties of heme. Trends Immunol (2003) 5.34

Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol (1996) 3.72

Regulation of NADPH oxidases: the role of Rac proteins. Circ Res (2006) 3.16

Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J (2001) 2.32

NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid Redox Signal (2009) 2.29

Essential role of extracellular SOD in reparative neovascularization induced by hindlimb ischemia. Circ Res (2007) 2.15

Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis. Circ Res (2015) 2.01

Mitochondrial generation of free radicals and hypoxic signaling. Trends Endocrinol Metab (2009) 1.98

Haem oxygenase-1 prevents cell death by regulating cellular iron. Nat Cell Biol (1999) 1.93

The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation. Antioxid Redox Signal (2006) 1.75

Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds. Carcinogenesis (2009) 1.61

Human microvascular endothelial cells immortalized with human telomerase catalytic protein: a model for the study of in vitro angiogenesis. Biochem Biophys Res Commun (2004) 1.56

NADPH oxidase-derived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes. Am J Pathol (2006) 1.39

Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells. Cardiovasc Res (2008) 1.37

The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. J Biol Chem (2011) 1.36

Effects of palmitate on Ca(2+) handling in adult control and ob/ob cardiomyocytes: impact of mitochondrial reactive oxygen species. Diabetes (2007) 1.31

The role of the Bcl-2 protein family in cancer. Semin Cancer Biol (2003) 1.31

Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial-nuclear network. Free Radic Biol Med (2014) 1.15

Chemopreventive agent resveratrol, a natural product derived from grapes, reversibly inhibits progression through S and G2 phases of the cell cycle in U937 cells. Cancer Lett (2001) 1.05

Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species. Free Radic Biol Med (2007) 1.05

Genetic ablation of the transcription repressor Bach1 leads to myocardial protection against ischemia/reperfusion in mice. Genes Cells (2006) 1.02

NADPH oxidase 4 mediates insulin-stimulated HIF-1α and VEGF expression, and angiogenesis in vitro. PLoS One (2012) 1.01

Cell death and autophagy under oxidative stress: roles of poly(ADP-Ribose) polymerases and Ca(2+). Mol Cell Biol (2012) 0.99

Protective role of heme oxygenase-1 against liver damage caused by hepatic ischemia and reperfusion in rats. Antioxid Redox Signal (2010) 0.94

Opportunity nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease. Cardiovasc Ther (2012) 0.94

Caspases and their role in gastric cancer. Adv Clin Exp Med (2013) 0.92

Caspases, apoptosis and aging. Ageing Res Rev (2003) 0.89

Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: role of IL-6. Free Radic Biol Med (2009) 0.86

Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model. J Clin Biochem Nutr (2010) 0.86

Bach1 deficiency protects pancreatic β-cells from oxidative stress injury. Am J Physiol Endocrinol Metab (2013) 0.85

Ablation of the bach1 gene leads to the suppression of atherosclerosis in bach1 and apolipoprotein E double knockout mice. Hypertens Res (2008) 0.81

Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism. FEBS Lett (2012) 0.81

Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency. Free Radic Res (2011) 0.80

Nox2 contributes to the arterial endothelial specification of mouse induced pluripotent stem cells by upregulating Notch signaling. Sci Rep (2016) 0.75

The Transcription Factor Bach1 Suppresses the Developmental Angiogenesis of Zebrafish. Oxid Med Cell Longev (2017) 0.75

Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation. Circ Res (2022) 0.75