Prolonged Inner Retinal Photoreception Depends on the Visual Retinoid Cycle.

Mechanisms creating transient and sustained photoresponses in mammalian retinal ganglion cells. J Gen Physiol (2017) 0.76

Phototransduction by retinal ganglion cells that set the circadian clock. Science (2002) 10.42

Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy. Nat Genet (1997) 4.87

Mutations in RPE65 cause Leber's congenital amaurosis. Nat Genet (1997) 4.48

Melanopsin is required for non-image-forming photic responses in blind mice. Science (2003) 4.22

Differential effect of the rd mutation on rods and cones in the mouse retina. Invest Ophthalmol Vis Sci (1978) 3.30

Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision. Neuron (2010) 2.91

Local retinal circuits of melanopsin-containing ganglion cells identified by transsynaptic viral tracing. Curr Biol (2007) 2.89

Addition of human melanopsin renders mammalian cells photoresponsive. Nature (2005) 2.63

Illumination of the melanopsin signaling pathway. Science (2005) 2.58

Immunocytochemical localization of two retinoid-binding proteins in vertebrate retina. J Cell Biol (1983) 2.29

Photon capture and signalling by melanopsin retinal ganglion cells. Nature (2008) 2.08

Photoreceptor adaptation in intrinsically photosensitive retinal ganglion cells. Neuron (2005) 1.96

Isorhodopsin rather than rhodopsin mediates rod function in RPE65 knock-out mice. Proc Natl Acad Sci U S A (2003) 1.94

Melanopsin-dependent nonvisual responses: evidence for photopigment bistability in vivo. J Biol Rhythms (2007) 1.88

Cephalochordate melanopsin: evolutionary linkage between invertebrate visual cells and vertebrate photosensitive retinal ganglion cells. Curr Biol (2005) 1.81

The cone-specific visual cycle. Prog Retin Eye Res (2010) 1.78

Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy. Proc Natl Acad Sci U S A (2001) 1.67

Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin. Proc Natl Acad Sci U S A (2005) 1.54

Transduction in invertebrate photoreceptors: role of pigment bistability. Physiol Rev (1983) 1.43

Melanopsin bistability: a fly's eye technology in the human retina. PLoS One (2009) 1.37

Functional diversity of melanopsins and their global expression in the teleost retina. Cell Mol Life Sci (2011) 1.23

A retinal ganglion cell that can signal irradiance continuously for 10 hours. J Neurosci (2012) 1.22

Waking State: Rapid Variations Modulate Neural and Behavioral Responses. Neuron (2015) 1.22

A "melanopic" spectral efficiency function predicts the sensitivity of melanopsin photoreceptors to polychromatic lights. J Biol Rhythms (2011) 1.21

Photochemistry of retinal chromophore in mouse melanopsin. Proc Natl Acad Sci U S A (2008) 1.16

Isotretinoin and psychopathology: a review. Ann Gen Psychiatry (2009) 1.16

Melanopsin and mechanisms of non-visual ocular photoreception. J Biol Chem (2011) 1.12

Requirement for an enzymatic visual cycle in Drosophila. Curr Biol (2009) 1.11

Inner retinal photoreception independent of the visual retinoid cycle. Proc Natl Acad Sci U S A (2006) 1.09

Nonvisual light responses in the Rpe65 knockout mouse: rod loss restores sensitivity to the melanopsin system. Proc Natl Acad Sci U S A (2006) 1.08

Melanopsin is highly resistant to light and chemical bleaching in vivo. J Biol Chem (2012) 1.06

Abnormal retinal function associated with isotretinoin therapy for acne. Arch Ophthalmol (1986) 1.03

Photochemical properties of mammalian melanopsin. Biochemistry (2012) 1.00

Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity. J Biol Chem (2011) 0.99

Destruction of Müller cells in the adult rat by intravitreal injection of D,L-alpha-aminoadipic acid. An electron microscopic study. Exp Eye Res (1979) 0.98

Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice. Proc Natl Acad Sci U S A (2001) 0.97

The rat retina has five types of ganglion-cell photoreceptors. Exp Eye Res (2014) 0.93

Melanopsin tristability for sustained and broadband phototransduction. Neuron (2015) 0.91

CRALBP supports the mammalian retinal visual cycle and cone vision. J Clin Invest (2015) 0.90

Small-molecule antagonists of melanopsin-mediated phototransduction. Nat Chem Biol (2013) 0.88

Effects of alpha-aminoadipate isomers on the morphology of the isolated chick embryo retina. Invest Ophthalmol Vis Sci (1983) 0.86

The influence of NaIO(3)-induced retinal degeneration on intra-retinal layer and the changes of expression profile/morphology of DA-ACs and mRGCS. Mol Neurobiol (2012) 0.81

Antiandrogenic effect of isotretinoin: is the retina involved in mechanism of action? Med Hypotheses (2007) 0.79

Melatonin modulates M4-type ganglion-cell photoreceptors. Neuroscience (2015) 0.77