Published in Oncol Res on January 01, 2016
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol (2008) 23.93
Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial. Lancet Oncol (2013) 4.20
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse. Nat Med (2003) 4.03
Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology. Nat Med (2006) 3.74
Antiretroviral therapies in women after single-dose nevirapine exposure. N Engl J Med (2010) 3.14
Whole-genome annotation by using evidence integration in functional-linkage networks. Proc Natl Acad Sci U S A (2004) 2.93
Regulation of T cell development by the deubiquitinating enzyme CYLD. Nat Immunol (2006) 2.73
Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses. J Exp Med (2007) 2.14
Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Dev Cell (2007) 2.05
Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production. Nat Immunol (2009) 1.86
An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists. Proc Natl Acad Sci U S A (2007) 1.85
Structural bias in T4 RNA ligase-mediated 3'-adapter ligation. Nucleic Acids Res (2012) 1.81
Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes. J Biol Chem (2011) 1.80
Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD. J Biol Chem (2008) 1.78
IkappaB kinase is an essential component of the Tpl2 signaling pathway. Mol Cell Biol (2004) 1.76
EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells. PLoS One (2011) 1.73
Discrimination of methylcytosine from hydroxymethylcytosine in DNA molecules. J Am Chem Soc (2010) 1.59
Association of interleukin-6 circulating levels with coronary artery disease: a meta-analysis implementing mendelian randomization approach. Int J Cardiol (2012) 1.57
Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin. J Clin Invest (2006) 1.53
Calcium- and myosin-dependent changes in troponin structure during activation of heart muscle. J Physiol (2008) 1.46
Scanning electron microscopic study of third-instar warbles in yak in China. Vet Parasitol (2004) 1.45
Preconditioning with prolonged oxygen exposure induces ischemic tolerance in the brain via oxygen free radical formation. Can J Anaesth (2004) 1.45
ERβ and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells. Cancer Biol Ther (2011) 1.45
Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma according to baseline status: subset analyses of the phase III Sorafenib Asia-Pacific trial. Eur J Cancer (2012) 1.45
The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity. Nat Immunol (2011) 1.45
Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine. Proc Natl Acad Sci U S A (2011) 1.42
Right ventricular outflow pacing induces less regional wall motion abnormalities in the left ventricle compared with apical pacing. Europace (2011) 1.42
Cytochrome oxidase I gene sequence of Hypoderma sinense infecting yaks in the Qinghai-Tibet high plateau of China. Vet Parasitol (2004) 1.41
Extracellular matrix metalloproteinase inducer (CD147) confers resistance of breast cancer cells to Anoikis through inhibition of Bim. J Biol Chem (2006) 1.41
Bevacizumab plus capecitabine and cisplatin in Chinese patients with inoperable locally advanced or metastatic gastric or gastroesophageal junction cancer: randomized, double-blind, phase III study (AVATAR study). Gastric Cancer (2014) 1.41
High-resolution enzymatic mapping of genomic 5-hydroxymethylcytosine in mouse embryonic stem cells. Cell Rep (2013) 1.40
Acute type B aortic intramural hematoma: treatment strategy and the role of endovascular repair. J Endovasc Ther (2010) 1.38
Osteoblasts directly control lineage commitment of mesenchymal progenitor cells through Wnt signaling. J Biol Chem (2007) 1.37
Nevirapine pharmacokinetics and risk of rash and hepatitis among HIV-infected sub-Saharan African women. AIDS (2012) 1.35
No risk of myocardial infarction associated with initial antiretroviral treatment containing abacavir: short and long-term results from ACTG A5001/ALLRT. Clin Infect Dis (2011) 1.32
The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. Immunity (2010) 1.31
A type IV modification-dependent restriction enzyme SauUSI from Staphylococcus aureus subsp. aureus USA300. Nucleic Acids Res (2011) 1.31
Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer. Breast Cancer Res (2007) 1.29
Unique small molecule entry inhibitors of hemorrhagic fever arenaviruses. J Biol Chem (2008) 1.29
Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection. BMC Med (2010) 1.26
GIS-based spatial regression and prediction of water quality in river networks: a case study in Iowa. J Environ Manage (2010) 1.25
The MspJI family of modification-dependent restriction endonucleases for epigenetic studies. Proc Natl Acad Sci U S A (2011) 1.25
A further investigation of health-related quality of life over time among men with HIV infection in the HAART era. Qual Life Res (2007) 1.23
Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphate-regulated potassium channels after focal cerebral ischemia in rats. Anesth Analg (2003) 1.23
A new strategy for structure determination of large proteins in solution without deuteration. Nat Methods (2006) 1.22
Autophagy inhibition enhances daunorubicin-induced apoptosis in K562 cells. PLoS One (2011) 1.22
Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis. Cancer Res (2010) 1.22
Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements. Hum Mol Genet (2004) 1.18
miR-9 regulation of BRCA1 and ovarian cancer sensitivity to cisplatin and PARP inhibition. J Natl Cancer Inst (2013) 1.18
Nevirapine- versus lopinavir/ritonavir-based initial therapy for HIV-1 infection among women in Africa: a randomized trial. PLoS Med (2012) 1.15
FoxM1 in tumorigenicity of the neuroblastoma cells and renewal of the neural progenitors. Cancer Res (2011) 1.15
The left renal entrapment syndrome: diagnosis and treatment. Ann Vasc Surg (2007) 1.14
Diversity and distribution of sediment nirS-encoding bacterial assemblages in response to environmental gradients in the eutrophied Jiaozhou Bay, China. Microb Ecol (2008) 1.12
Identification of a novel human angiopoietin-like gene expressed mainly in heart. J Hum Genet (2003) 1.11
Lethal effect of imidacloprid on the coccinellid predator Serangium japonicum and sublethal effects on predator voracity and on functional response to the whitefly Bemisia tabaci. Ecotoxicology (2012) 1.10
Identification of beta-catenin as a target of the intracellular tyrosine kinase PTK6. J Cell Sci (2009) 1.10
Occurrence, source, and human infection potential of cryptosporidium and Giardia spp. in source and tap water in shanghai, china. Appl Environ Microbiol (2011) 1.10
Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc. BMC Cancer (2010) 1.08
Comprehensive analysis of NAC domain transcription factor gene family in Vitis vinifera. Plant Cell Rep (2012) 1.08
Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles. Eur J Pharm Sci (2009) 1.06
Water-soluble superparamagnetic manganese ferrite nanoparticles for magnetic resonance imaging. Biomaterials (2010) 1.06
Contrasting selection pressures on components of the Ras-mediated signal transduction pathway in Drosophila. Mol Ecol (2003) 1.06
Novel plasma phospholipid biomarkers of autism: mitochondrial dysfunction as a putative causative mechanism. Prostaglandins Leukot Essent Fatty Acids (2009) 1.06
NMR solution structure and dynamics of an exchangeable apolipoprotein, Locusta migratoria apolipophorin III. J Biol Chem (2003) 1.05
Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion. Ann Clin Lab Sci (2008) 1.05
Comparative characterization of the PvuRts1I family of restriction enzymes and their application in mapping genomic 5-hydroxymethylcytosine. Nucleic Acids Res (2011) 1.05
Novel thienopyridine derivatives as specific anti-hepatocellular carcinoma (HCC) agents: synthesis, preliminary structure-activity relationships, and in vitro biological evaluation. Bioorg Med Chem Lett (2010) 1.05
Multiple system utilization and mortality for veterans with stroke. Stroke (2006) 1.05
Fiber-tip micro-cavity for temperature and transverse load sensing. Opt Express (2011) 1.05
Change in high-sensitivity c-reactive protein levels following initiation of efavirenz-based antiretroviral regimens in HIV-infected individuals. AIDS Res Hum Retroviruses (2010) 1.04
Assessment of potential sublethal effects of various insecticides on key biological traits of the tobacco whitefly, Bemisia tabaci. Int J Biol Sci (2013) 1.03
Characterization and crystal structure of the type IIG restriction endonuclease RM.BpuSI. Nucleic Acids Res (2011) 1.03
Biochemical characterization of recombinant β-glucosyltransferase and analysis of global 5-hydroxymethylcytosine in unique genomes. Biochemistry (2012) 1.03
Characterization of type II and III restriction-modification systems from Bacillus cereus strains ATCC 10987 and ATCC 14579. J Bacteriol (2011) 1.01
Overexpression of Rab25 contributes to metastasis of bladder cancer through induction of epithelial-mesenchymal transition and activation of Akt/GSK-3β/Snail signaling. Carcinogenesis (2013) 1.01
Expression of the splicing regulator polypyrimidine tract-binding protein in normal and neoplastic brain. Neuro Oncol (2004) 1.01
Association between single nucleotide polymorphisms in deoxycytidine kinase and treatment response among acute myeloid leukaemia patients. Pharmacogenetics (2004) 1.00
Structural long period gratings made by drilling micro-holes in photonic crystal fibers with a femtosecond infrared laser. Opt Express (2010) 1.00
Sequence-specific assignments of methyl groups in high-molecular weight proteins. J Am Chem Soc (2004) 1.00
Interleukin-23: immunological roles and clinical implications. Int J Biochem Cell Biol (2008) 1.00
Micelles based on methoxy poly(ethylene glycol)-cholesterol conjugate for controlled and targeted drug delivery of a poorly water soluble drug. J Biomed Nanotechnol (2012) 1.00
Identification of the functional role of AF1Q in the progression of breast cancer. Breast Cancer Res Treat (2007) 1.00
Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter. Proc Natl Acad Sci U S A (2010) 1.00
Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA Stability. Oncotarget (2014) 0.99
Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development. Proc Natl Acad Sci U S A (2011) 0.99
Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease. Nucleic Acids Res (2012) 0.98
Ketamine potentiates hippocampal neurodegeneration and persistent learning and memory impairment through the PKCγ-ERK signaling pathway in the developing brain. Brain Res (2012) 0.97
Histone deacetylase 3 inhibits expression of PUMA in gastric cancer cells. J Mol Med (Berl) (2012) 0.97
Variants in exon 11 of MEF2A gene and coronary artery disease: evidence from a case-control study, systematic review, and meta-analysis. PLoS One (2012) 0.97
Characterization and genomic analysis of kraft lignin biodegradation by the beta-proteobacterium Cupriavidus basilensis B-8. Biotechnol Biofuels (2013) 0.97
Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma. J Pharm Sci (2010) 0.97
Tumor associated macrophage × cancer cell hybrids may acquire cancer stem cell properties in breast cancer. PLoS One (2012) 0.96
Structural-acoustic coupling effects on the non-vacuum packaging vibratory cylinder gyroscope. Sensors (Basel) (2013) 0.96
HIV-1 protease inhibitors and clinical malaria: a secondary analysis of the AIDS Clinical Trials Group A5208 study. Antimicrob Agents Chemother (2011) 0.96
Self-priming compartmentalization digital LAMP for point-of-care. Lab Chip (2012) 0.95
Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells. Cell Cycle (2010) 0.95
Profiling a Caenorhabditis elegans behavioral parametric dataset with a supervised K-means clustering algorithm identifies genetic networks regulating locomotion. J Neurosci Methods (2011) 0.95
Phylogenetic utility of nuclear introns in interfamilial relationships of Caniformia (order Carnivora). Syst Biol (2011) 0.95
Trichostatin A, a histone deacetylase inhibitor, reduces lesion growth and hyperalgesia in experimentally induced endometriosis in mice. Hum Reprod (2010) 0.95