Co-inhibition of colony stimulating factor-1 receptor and BRAF oncogene in mouse models of BRAF(V600E) melanoma.

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Published in Oncoimmunology on December 10, 2015

Authors

Shin Foong Ngiow1, Katrina M Meeth2, Kimberley Stannard3, Deborah S Barkauskas3, Gideon Bollag4, Marcus Bosenberg5, Mark J Smyth1

Author Affiliations

1: Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland Australia; School of Medicine, The University of Queensland, Herston, Queensland, Australia.
2: Department of Pathology, Yale University , New Haven, CT, USA.
3: Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute , Herston, Queensland Australia.
4: Plexxikon Inc , Berkeley, CA, USA.
5: Department of Pathology, Yale University, New Haven, CT, USA; Department of Dermatology, Yale University; New Haven, CT, USA.

Associated clinical trials:

A Phase 1b Open Label, Dose Escalation Study of PLX3397 in Combination With Vemurafenib in V600-mutated BRAF Melanoma | NCT01826448

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