Aptamer-nanoparticle complexes as powerful diagnostic and therapeutic tools.

PubWeight™: 0.80‹?›

🔗 View Article (PMID 27151454)

Published in Exp Mol Med on May 06, 2016

Authors

Hunho Jo1, Changill Ban1

Author Affiliations

1: Department of Chemistry, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea.

Articles cited by this

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science (1990) 35.96

In vitro selection of RNA molecules that bind specific ligands. Nature (1990) 30.19

Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew Chem Int Ed Engl (2007) 6.32

Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clin Chem (1999) 5.22

Aptamers: an emerging class of therapeutics. Annu Rev Med (2005) 4.15

Chemotherapy-induced nausea and vomiting. N Engl J Med (2008) 4.00

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nat Biotechnol (2009) 3.78

Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins. Cell (2011) 3.40

In vivo magnetic resonance imaging of transgene expression. Nat Med (2000) 3.35

Atomic accuracy in predicting and designing noncanonical RNA structure. Nat Methods (2010) 3.07

FR3D: finding local and composite recurrent structural motifs in RNA 3D structures. J Math Biol (2007) 2.81

Development of DNA aptamers using Cell-SELEX. Nat Protoc (2010) 2.62

Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett (2007) 2.40

Gold nanoparticle-based colorimetric assay for the direct detection of cancerous cells. Anal Chem (2008) 1.84

Aptamer-functionalized Au nanoparticles for the amplified optical detection of thrombin. J Am Chem Soc (2004) 1.64

First-in-human evaluation of anti von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers. Circulation (2007) 1.51

Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing. Mol Cell Biol (2012) 1.49

Aptamers--basic research, drug development, and clinical applications. Appl Microbiol Biotechnol (2005) 1.46

Thermally cross-linked superparamagnetic iron oxide nanoparticles: synthesis and application as a dual imaging probe for cancer in vivo. J Am Chem Soc (2007) 1.45

Bioconjugated nanoparticles for DNA protection from cleavage. J Am Chem Soc (2003) 1.39

Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease Therapy. Mol Ther Nucleic Acids (2014) 1.32

Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy. ACS Nano (2012) 1.32

Aptamers selected for higher-affinity binding are not more specific for the target ligand. J Am Chem Soc (2006) 1.28

Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes. Diabetologia (2009) 1.21

In vitro selection of aptamers with affinity for neuropeptide Y using capillary electrophoresis. J Am Chem Soc (2005) 1.15

Nucleic acid conjugated nanomaterials for enhanced molecular recognition. ACS Nano (2009) 1.13

In silico selection of RNA aptamers. Nucleic Acids Res (2009) 1.09

A liposome-based nanostructure for aptamer directed delivery. Chem Commun (Camb) (2009) 1.07

Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA (+) and PSMA (-) prostate cancers. Biomaterials (2010) 1.07

Current approaches in SELEX: An update to aptamer selection technology. Biotechnol Adv (2015) 1.06

Release of photoactivatable drugs from plasmonic nanoparticles for targeted cancer therapy. ACS Nano (2011) 1.06

Functional DNA-containing nanomaterials: cellular applications in biosensing, imaging, and targeted therapy. Acc Chem Res (2014) 1.05

Aptamer-conjugated nanomaterials and their applications. Adv Drug Deliv Rev (2011) 1.03

Analytical performances of aptamer-based sensing for thrombin detection. Anal Chem (2007) 1.00

Gold nanostructures as a platform for combinational therapy in future cancer therapeutics. Cancers (Basel) (2011) 1.00

Integrated microfluidic system for rapid screening of CRP aptamers utilizing systematic evolution of ligands by exponential enrichment (SELEX). Biosens Bioelectron (2009) 0.99

In vitro selection and characterization of RNA aptamers binding thyroxine hormone. Biochem J (2007) 0.95

Nano aptasensor for protective antigen toxin of anthrax. Anal Chem (2010) 0.95

MPBind: a Meta-motif-based statistical framework and pipeline to Predict Binding potential of SELEX-derived aptamers. Bioinformatics (2014) 0.95

Nanomechanical microcantilever operated in vibration modes with use of RNA aptamer as receptor molecules for label-free detection of HCV helicase. Biosens Bioelectron (2007) 0.95

Detection of aptamer-protein interactions using QCM and electrochemical indicator methods. Bioorg Med Chem Lett (2005) 0.93

A colorimetric aptasensor for the diagnosis of malaria based on cationic polymers and gold nanoparticles. Anal Biochem (2013) 0.89

Single quantum-dot-based aptameric nanosensor for cocaine. Anal Chem (2009) 0.88

MUC-1 aptamer-conjugated dye-doped silica nanoparticles for MCF-7 cells detection. Biomaterials (2012) 0.88

Single-stranded DNA aptamers specific for antibiotics tetracyclines. Bioorg Med Chem (2008) 0.87

Aptasensor for ampicillin using gold nanoparticle based dual fluorescence-colorimetric methods. Anal Bioanal Chem (2012) 0.85

Quantum dot-nucleic acid/aptamer bioconjugate-based fluorimetric biosensors. Biochem Soc Trans (2012) 0.84

Dual aptamer-functionalized silica nanoparticles for the highly sensitive detection of breast cancer. Biosens Bioelectron (2015) 0.83

A label-free aptamer-fluorophore assembly for rapid and specific detection of cocaine in biofluids. Anal Chem (2014) 0.82

Detection of lysozyme magnetic relaxation switches based on aptamer-functionalized superparamagnetic nanoparticles. Anal Chem (2011) 0.80

Electrochemical aptasensor for mucin 1 based on dual signal amplification of poly(o-phenylenediamine) carrier and functionalized carbon nanotubes tracing tag. Biosens Bioelectron (2014) 0.79

Solubilization of flurbiprofen into aptamer-modified PEG-PLA micelles for targeted delivery to brain-derived endothelial cells in vitro. J Microencapsul (2013) 0.78

Electrochemical Aptasensor of Cardiac Troponin I for the Early Diagnosis of Acute Myocardial Infarction. Anal Chem (2015) 0.76