Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 trial.

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🔗 View Article (PMID 27155741)

Published in Lancet Oncol on May 04, 2016

Authors

Ian E Krop1, Ingrid A Mayer2, Vinod Ganju3, Maura Dickler4, Stephen Johnston5, Serafin Morales6, Denise A Yardley7, Bohuslav Melichar8, Andres Forero-Torres9, Soo Chin Lee10, Richard de Boer11, Katarina Petrakova12, Susanne Vallentin13, Edith A Perez14, Martine Piccart15, Matthew Ellis16, Eric Winer17, Steven Gendreau18, Mika Derynck18, Mark Lackner18, Gallia Levy18, Jiaheng Qiu18, Jing He18, Peter Schmid19

Author Affiliations

1: Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address: ian_krop@dfci.harvard.edu.
2: Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
3: Peninsula Oncology Centre, Melbourne, VIC, Australia.
4: Memorial Sloan Kettering Cancer Center, New York, NY, USA.
5: The Royal Marsden Hospital, London, UK.
6: Hospital Arnau de Vilanova, Lleida, Spain.
7: Sarah Cannon Research Institute, and Tennessee Oncology, Nashville, TN, USA.
8: Palacky University Medical School and Teaching Hospital, Olomouc, Czech Republic.
9: University of Alabama, Birmingham, AL, USA.
10: National University Hospital, Singapore.
11: Royal Melbourne Hospital, Parkville, VIC, Australia.
12: Masaryk Memorial Cancer Institute, Brno, Czech Republic.
13: Herlev University Hospital, Copenhagen, Denmark.
14: Mayo Clinic, Jacksonville, FL, USA.
15: Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
16: Washington University School of Medicine, St Louis, MO, USA.
17: Dana-Farber Cancer Institute, Boston, MA, USA.
18: Genentech, South San Francisco, CA, USA.
19: Barts Cancer Institute, Queen Mary University of London, London, UK.

Associated clinical trials:

Study of GDC-0941 or GDC-0980 With Fulvestrant Versus Fulvestrant in Advanced or Metastatic Breast Cancer in Participants Resistant to Aromatase Inhibitor Therapy | NCT01437566

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