Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system.

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Published in Oncogene on May 09, 2016

Authors

M G Varga1, C L Shaffer2, J C Sierra3, G Suarez3, M B Piazuelo3, M E Whitaker3, J Romero-Gallo3, U S Krishna3, A Delgado3, M A Gomez4, J A D Good5,6, F Almqvist5,6, E P Skaar2,7, P Correa3, K T Wilson1,2,3,7, M Hadjifrangiskou2, R M Peek1,2,3

Author Affiliations

1: Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN, USA.
2: Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA.
3: Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
4: Department of Internal Medicine, Unit of Gastroenterology, National University of Colombia School of Medicine, Bogota, Colombia.
5: Department of Chemistry, Umeå University, Umeå, Sweden.
6: Umeå Centre for Microbial Research, Umeå University, Umeå, Sweden.
7: Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN, USA.

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