Published in J R Soc Med on April 01, 1989
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The characterization of human epidermal filaggrin. A histidine-rich, keratin filament-aggregating protein. Biochim Biophys Acta (1983) 1.25
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Characterization of two monoclonal antibodies to human epidermal keratohyalin: reactivity with filaggrin and related proteins. J Invest Dermatol (1987) 1.17
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Ichthyosis vulgaris: identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules. J Invest Dermatol (1985) 1.14
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A phosphorylated keratohyalin-derived precursor of epidermal stratum corneum basic protein. J Biol Chem (1980) 1.08
Identification of proteolytic cleavage sites in the conversion of profilaggrin to filaggrin in mammalian epidermis. J Biol Chem (1989) 1.08
Identification of two intermediates during processing of profilaggrin to filaggrin in neonatal mouse epidermis. J Cell Biol (1984) 1.08
The identification of fibrous proteins in fetal rat epidermis by electrophoretic and immunologic techniques. J Invest Dermatol (1976) 1.08
Profilaggrin, a high-molecular-weight precursor of filaggrin in human epidermis and cultured keratinocytes. J Invest Dermatol (1985) 1.03
Regulated expression of human filaggrin in keratinocytes results in cytoskeletal disruption, loss of cell-cell adhesion, and cell cycle arrest. Exp Cell Res (2001) 1.01
Translocation of profilaggrin N-terminal domain into keratinocyte nuclei with fragmented DNA in normal human skin and loricrin keratoderma. Lab Invest (1998) 1.01
Expression of defensins in gingiva and their role in periodontal health and disease. Curr Pharm Des (2007) 1.01
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Interaction of filaggrin with keratin filaments during advanced stages of normal human epidermal differentiation and in ichthyosis vulgaris. Differentiation (1991) 0.99
Multiple copies of phosphorylated filaggrin in epidermal profilaggrin demonstrated by analysis of tryptic peptides. Biochemistry (1985) 0.99
Streptococcus bovis septicaemia associated with uncomplicated colonic carcinoma. Br J Surg (1991) 0.98
Arrested epidermal morphogenesis in three newborn infants with a fatal genetic disorder (restrictive dermopathy). J Invest Dermatol (1987) 0.97
Independent regulation of two cytoplasmic processing stages of the intermediate filament-associated protein filaggrin and role of Ca2+ in the second stage. J Biol Chem (1993) 0.97
Pseudomonas paucimobilis contamination of cool mist tents on a paediatric ward. J Hosp Infect (1986) 0.97
Expression of the antimicrobial peptide, human beta-defensin 1, in duct cells of minor salivary glands and detection in saliva. J Dent Res (2000) 0.97
Characterization of a phosphorylated form of the intermediate filament-aggregating protein filaggrin. Biochemistry (1982) 0.96
High-molecular-weight precursor of epidermal filaggrin and hypothesis for its tandem repeating structure. Biochemistry (1984) 0.95
Evidence for specific proteolytic cleavage of the N-terminal domain of human profilaggrin during epidermal differentiation. J Invest Dermatol (1997) 0.94
Epidermolytic hyperkeratosis: ultrastructure and biochemistry of skin and amniotic fluid cells from two affected fetuses and a newborn infant. J Invest Dermatol (1983) 0.94
Immunologic localization of filaggrin in human oral epithelia and correlation with keratinization. J Invest Dermatol (1986) 0.93
Characterization of two distinct calcium-binding sites in the amino-terminus of human profilaggrin. J Invest Dermatol (1995) 0.92
Evidence of a precursor form of stratum corneum basic protein in rat epidermis. Biochemistry (1979) 0.92
Intracranial suppuration 1968-1982--a 15 year review. Clin Otolaryngol Allied Sci (1984) 0.92
Characterization of hair follicle bulge in human fetal skin: the human fetal bulge is a pool of undifferentiated keratinocytes. J Invest Dermatol (1995) 0.92
Abnormal epidermal keratinization in the repeated epilation mutant mouse. J Cell Biol (1982) 0.91
The repetitive structure of the profilaggrin gene as demonstrated using epidermal profilaggrin cDNA. J Biol Chem (1986) 0.91
Differential utilization of nuclear factor-kappaB signaling pathways for gingival epithelial cell responses to oral commensal and pathogenic bacteria. Oral Microbiol Immunol (2008) 0.91
Filaggrin, the matrix protein of keratin. Am J Dermatopathol (1985) 0.91
Regional difference in expression of characteristic abnormality of harlequin ichthyosis in affected fetuses. Prenat Diagn (1998) 0.89
The complications of sphenoid sinusitis. J Laryngol Otol (1983) 0.89
Expression of a truncated keratin 5 may contribute to severe palmar--plantar hyperkeratosis in epidermolysis bullosa simplex patients. J Invest Dermatol (2001) 0.89
Localization of profilaggrin mRNA in newborn rat skin by in situ hybridization. J Invest Dermatol (1987) 0.88
Novel and recurring ABCA12 mutations associated with harlequin ichthyosis: implications for prenatal diagnosis. Br J Dermatol (2007) 0.88
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of proteins of newbonr rat skin. II. Keratohyalin and stratum corneum proteins. J Invest Dermatol (1975) 0.88
Adrenergic signaling in human oral keratinocytes and wound repair. J Dent Res (2010) 0.88
Cyanogen bromide cleavage of proteins in sodium dodecyl sulphate/polyacrylamide gels. Diagonal peptide mapping of proteins from epidermis. Biochem J (1981) 0.88
Decreased profilaggrin expression in ichthyosis vulgaris is a result of selectively impaired posttranscriptional control. J Biol Chem (1995) 0.87
Similarities between stratum corneum basic protein and histidine-rich protein II from newborn rat epidermis. Biochim Biophys Acta (1981) 0.87
An outbreak of group A haemolytic streptococcal puerperal sepsis spread by the communal use of bidets. Br J Obstet Gynaecol (1994) 0.87
Bullous myringitis: a review. Clin Otolaryngol Allied Sci (1997) 0.86
Intracellular calcium in signaling human beta-defensin-2 expression in oral epithelial cells. J Dent Res (2003) 0.86
Keratinocytes cultured from subjects with ichthyosis vulgaris are phenotypically abnormal. J Invest Dermatol (1987) 0.86
Stratum corneum basic protein: an interfilamentous matrix protein of epidermal keratin. Curr Probl Dermatol (1980) 0.86
Filaggrin, an intermediate filament-associated protein: structural and functional implications from the sequence of a cDNA from rat. DNA Cell Biol (1990) 0.85
Streptococcus bovis endocarditis and colonic carcinoma: a neglected association. Br Med J (Clin Res Ed) (1983) 0.85
TGF-beta1 Inhibits TLR-mediated odontoblast responses to oral bacteria. J Dent Res (2009) 0.84
Primary meningococcal conjunctivitis and the need for prophylaxis in close contacts. J Infect (1994) 0.84
Changes in cell phenotype during regeneration of junctional epithelium of human gingiva in vitro. J Periodontal Res (1989) 0.84
Identification of rat epidermal profilaggrin phosphatase as a member of the protein phosphatase 2A family. J Cell Sci (1993) 0.84
Retinoic acid regulates oral epithelial differentiation by two mechanisms. J Invest Dermatol (1995) 0.84
Inducible expression of filaggrin increases keratinocyte susceptibility to apoptotic cell death. Cell Death Differ (2000) 0.84
Epidermal filaggrin is synthesized on a large messenger ribonucleic acid as a high-molecular-weight precursor. Biochemistry (1983) 0.84
Filaggrin production by cultured human epidermal keratinocytes and its regulation by retinoic acid. Differentiation (1990) 0.83
Profilaggrin requires both linker and filaggrin peptide sequences to form granules: implications for profilaggrin processing in vivo. J Invest Dermatol (1999) 0.83
Identification of filaggrin in cultured mouse keratinocytes and its regulation by calcium. J Invest Dermatol (1983) 0.83
Surgical decompression of the orbit. J R Coll Surg Edinb (1986) 0.83
Regulation of tyrosyl-transfer ribonucleic acid synthetase in Bacillus subtilis. J Bacteriol (1971) 0.82
Human oral epithelial cell culture. II. Keratin expression in fetal and adult gingival cells. In Vitro Cell Dev Biol (1990) 0.82
Distribution of histidine-rich basic protein, a possible keratin matrix protein, in rat oral epithelium. Arch Oral Biol (1982) 0.82
Two-dimensional analysis of proteins of rat oral epithelia and epidermis. Arch Oral Biol (1982) 0.82
Regulation of human profilaggrin promoter activity in cultured epithelial cells by retinoic acid and glucocorticoids. J Dermatol Sci (2001) 0.82
Antisense profilaggrin RNA delays and decreases profilaggrin expression and alters in vitro differentiation of rat epidermal keratinocytes. J Invest Dermatol (1993) 0.82
Immunohistochemical analysis of stratum corneum components in oral squamous epithelia. Differentiation (1989) 0.81
The calcium-activated neutral protease calpain I is present in normal foetal skin and is decreased in neonatal harlequin ichthyosis. Br J Dermatol (1999) 0.81
Hyperthyroidism due to a thyrotrophin-secreting microadenoma. Clin Endocrinol (Oxf) (1983) 0.81
Filaggrin expression in epidermolytic ichthyosis (epidermolytic hyperkeratosis). Br J Dermatol (1994) 0.80
Protein phosphatase activity in human keratinocytes cultured from normal epidermis and epidermis from patients with harlequin ichthyosis. Br J Dermatol (1997) 0.80
Harlequin ichthyosis keratinocytes in lifted culture differentiate poorly by morphologic and biochemical criteria. J Invest Dermatol (1997) 0.80
Distinctive expression of filaggrin and trichohyalin during various pathways of epithelial differentiation. Br J Dermatol (1997) 0.79
Epidermal growth factor receptors in genetically induced hyperproliferative skin disorders. Pediatr Dermatol (1990) 0.79
Immunohistochemical study of structural proteins in developing junctional epithelium. J Periodontol (1986) 0.79
Familial pityriasis rubra pilaris. Arch Dermatol (1995) 0.78
Repeated epilation (ER): a semidominant autosomal gene reducing synthesis of skin filaggrin in mice. Prog Clin Biol Res (1982) 0.78