Published in Amino Acids on May 12, 2016
Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation. J Biol Chem (1987) 4.99
Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease. J Biol Chem (1993) 3.52
Stability of protein pharmaceuticals. Pharm Res (1989) 2.92
beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease. Proc Natl Acad Sci U S A (1993) 2.80
Succinimide formation from aspartyl and asparaginyl peptides as a model for the spontaneous degradation of proteins. J Biol Chem (1989) 2.18
Aspartic acid racemization in tooth enamel from living humans. Proc Natl Acad Sci U S A (1975) 1.50
Aspartic acid racemisation in the human lens during ageing and in cataract formation. Nature (1977) 1.37
Synthetic peptide substrates for the erythrocyte protein carboxyl methyltransferase. Detection of a new site of methylation at isomerized L-aspartyl residues. J Biol Chem (1984) 1.23
Racemization of aspartic acid in human proteins. Ageing Res Rev (2002) 1.18
Determination of D- and L-aspartate in amino acid mixtures by high-performance liquid chromatography after derivatization with a chiral adduct of o-phthaldialdehyde. Anal Biochem (1984) 1.15
Recognition of D-aspartyl residues in polypeptides by the erythrocyte L-isoaspartyl/D-aspartyl protein methyltransferase. Implications for the repair hypothesis. J Biol Chem (1992) 1.13
Structural elements affecting the recognition of L-isoaspartyl residues by the L-isoaspartyl/D-aspartyl protein methyltransferase. Implications for the repair hypothesis. J Biol Chem (1991) 1.08
Racemization reaction of aspartic Acid and its use in dating fossil bones. Proc Natl Acad Sci U S A (1973) 1.06
Reactive oxygen species, isotope effect, essential nutrients, and enhanced longevity. Rejuvenation Res (2007) 1.06
Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation. Free Radic Biol Med (2012) 0.99
Racemisation and human cataract. D-Ser, D-Asp/Asn and D-Thr are higher in the lifelong proteins of cataract lenses than in age-matched normal lenses. Age (Dordr) (2010) 0.99
Protein L-isoaspartyl methyltransferase catalyzes in vivo racemization of Aspartate-25 in mammalian histone H2B. J Biol Chem (2005) 0.99
Age estimation by amino acid racemization in human teeth. J Forensic Sci (2010) 0.98
In vivo racemization in mammalian proteins. Methods Enzymol (1984) 0.94
Non-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae. J Biol Chem (2014) 0.92
Racemization of two proteins over our lifespan: deamidation of asparagine 76 in γS crystallin is greater in cataract than in normal lenses across the age range. Invest Ophthalmol Vis Sci (2012) 0.88
Identification of isomerization and racemization of aspartate in the Asp-Asp motifs of a therapeutic protein. Anal Biochem (2010) 0.88
The etiology of human age-related cataract. Proteins don't last forever. Biochim Biophys Acta (2015) 0.88
Age-dependent accumulation of protein residues which can be hydrolyzed to D-aspartic acid in human erythrocytes. J Biol Chem (1986) 0.88
Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress. Free Radic Biol Med (2015) 0.83
Mildly acidic conditions eliminate deamidation artifact during proteolysis: digestion with endoprotease Glu-C at pH 4.5. Amino Acids (2016) 0.83
Racemized and Isomerized Proteins in Aging Rat Teeth and Eye Lens. Rejuvenation Res (2016) 0.81
Racemization of the aspartic acid residue of amyloid-β peptide by a radical reaction. Biosci Biotechnol Biochem (2013) 0.79
Comparison of age estimated from degree of racemization of aspartic acid, glutamic acid and alanine in the femur. J Forensic Sci (2004) 0.78