Toward a noncytotoxic glioblastoma therapy: blocking MCP-1 with the MTZ Regimen.

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Published in Onco Targets Ther on April 27, 2016

Authors

Michael E Salacz1, Richard E Kast2, Najmaldin Saki3, Ansgar Brüning4, Georg Karpel-Massler5, Marc-Eric Halatsch5

Author Affiliations

1: Department of Internal Medicine, University of Kansas, Kansas City, KS, USA; Department of Neurosurgery, University of Kansas, Kansas City, KS, USA.
2: IIAIGC Study Center, Burlington, VT, USA.
3: Health Research Institute, Research Center of Thalassemia and Hemoglobinopathy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
4: Molecular Biology Laboratory, University Hospital Munich, Munich, Germany.
5: Department of Neurosurgery, University of Ulm, Ulm, Germany.

Associated clinical trials:

Repeat Radiation, Minocycline and Bevacizumab in Patients With Recurrent Glioma (RAMBO) | NCT01580969

Phase I Newly Diagnosed GBM With Temozolomide, Radiation, and Minocycline Followed by Adjuvant Minocycline/Temozolomide (D-TERMINED) (D-TERMINED) | NCT02272270

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