Cross-talk between 4-1BB and TLR1-TLR2 Signaling in CD8+ T Cells Regulates TLR2's Costimulatory Effects.

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🔗 View Article (PMID 27267778)

Published in Cancer Immunol Res on June 07, 2016

Authors

Ann Mary Joseph1, Ratika Srivastava2, Jovanny Zabaleta3, Eduardo Davila4

Author Affiliations

1: University of Maryland, Marlene and Stewart Greenebaum Cancer Center, Baltimore, Maryland. Department of Microbiology and Immunology, University of Maryland, Baltimore, Maryland.
2: University of Maryland, Marlene and Stewart Greenebaum Cancer Center, Baltimore, Maryland.
3: Department of Pediatrics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
4: University of Maryland, Marlene and Stewart Greenebaum Cancer Center, Baltimore, Maryland. Department of Microbiology and Immunology, University of Maryland, Baltimore, Maryland. edavila@som.umaryland.edu.

Associated clinical trials:

A Study Of PF-05082566 As A Single Agent And In Combination With Rituximab | NCT01307267

Phase II, 2nd Line Melanoma - RAND Monotherapy | NCT00612664

Combination Study of Urelumab and Rituximab in Patients With B-cell Non-Hodgkins Lymphoma | NCT01775631

A Study Of 4-1BB Agonist PF-05082566 Plus PD-1 Inhibitor MK-3475 In Patients With Solid Tumors (B1641003/KEYNOTE-0036) | NCT02179918

Combination Study of Urelumab and Cetuximab in Patients With Advanced/Metastatic Colorectal Cancer or Advanced/Metastatic Head and Neck Cancer | NCT02110082

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