Loss of epithelial FAM20A in mice causes amelogenesis imperfecta, tooth eruption delay and gingival overgrowth.

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Mutations in FAM20C also identified in non-lethal osteosclerotic bone dysplasia. Clin Genet (2009) 1.46

FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan-protein linkage region. Biochem J (2009) 1.45

Expression of FAM20C in the osteogenesis and odontogenesis of mouse. J Histochem Cytochem (2010) 1.33

Nephrocalcinosis (enamel renal syndrome) caused by autosomal recessive FAM20A mutations. Nephron Physiol (2013) 1.31

FAM20C plays an essential role in the formation of murine teeth. J Biol Chem (2012) 1.29

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Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice. Vet Pathol (2012) 1.18

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A secretory kinase complex regulates extracellular protein phosphorylation. Elife (2015) 1.05

Enamelin is critical for ameloblast integrity and enamel ultrastructure formation. PLoS One (2014) 0.94

FAM20A mutations associated with enamel renal syndrome. J Dent Res (2013) 0.92

Hypophosphatemic osteomalacia and bone sclerosis caused by a novel homozygous mutation of the FAM20C gene in an elderly man with a mild variant of Raine syndrome. Bone (2014) 0.89

Hereditary deletion of the entire FAM20C gene in a patient with Raine syndrome. Am J Med Genet A (2013) 0.87

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Inactivation of Fam20B in the dental epithelium of mice leads to supernumerary incisors. Eur J Oral Sci (2015) 0.79

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