The biophysical characterization of the first SCN5A mutation R1512W identified in Chinese sudden unexplained nocturnal death syndrome.

Vinculin variant M94I identified in sudden unexplained nocturnal death syndrome decreases cardiac sodium current. Sci Rep (2017) 0.75

A meta-analytic review of prevalence for Brugada ECG patterns and the risk for death. Medicine (Baltimore) (2016) 0.75

An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population. J Am Heart Assoc (2017) 0.75

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genet Med (2015) 16.87

Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing. Heart Rhythm (2004) 3.15

Cardiac sodium channel dysfunction in sudden infant death syndrome. Circulation (2007) 2.28

Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes. Cardiovasc Res (2000) 2.19

Common human SCN5A polymorphisms have altered electrophysiology when expressed in Q1077 splice variants. Heart Rhythm (2005) 2.18

Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome. Hum Mol Genet (2002) 2.16

A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels. Circ Res (2003) 2.07

Brugada syndrome. Circ Arrhythm Electrophysiol (2012) 2.03

A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y. J Clin Invest (2006) 1.79

New electrocardiographic leads and the procainamide test for the detection of the Brugada sign in sudden unexplained death syndrome survivors and their relatives. Eur Heart J (2001) 1.70

Changes in intracellular sodium and pH during ischaemia-reperfusion are attenuated by trimetazidine. Comparison between low- and zero-flow ischaemia. Cardiovasc Res (2000) 1.60

Human SCN5A gene mutations alter cardiac sodium channel kinetics and are associated with the Brugada syndrome. Cardiovasc Res (1999) 1.34

Sudden unexplained nocturnal death syndrome in Southern China: an epidemiological survey and SCN5A gene screening. Am J Forensic Med Pathol (2011) 1.17

The enigma of "bangungut". Ann Intern Med (1960) 1.14

Partial expression defect for the SCN5A missense mutation G1406R depends on splice variant background Q1077 and rescue by mexiletine. Am J Physiol Heart Circ Physiol (2006) 1.08

SCN5A rare variants in familial dilated cardiomyopathy decrease peak sodium current depending on the common polymorphism H558R and common splice variant Q1077del. Clin Transl Sci (2010) 1.07

Sudden unexplained death syndrome in north-east Thailand. Int J Epidemiol (1993) 0.97

Pokkuri Death Syndrome; sudden cardiac death cases without coronary atherosclerosis in South Asian young males. Forensic Sci Int (2010) 0.95

Is sudden unexplained nocturnal death syndrome in Southern China a cardiac sodium channel dysfunction disorder? Forensic Sci Int (2014) 0.95

Unique sleep disorders profile of a population-based sample of 747 Hmong immigrants in Wisconsin. Soc Sci Med (2012) 0.93

Is sudden unexplained nocturnal death a breathing disorder? Psychiatry Clin Neurosci (1995) 0.88

Postmortem molecular analysis of KCNQ1, KCNH2, KCNE1 and KCNE2 genes in sudden unexplained nocturnal death syndrome in the Chinese Han population. Forensic Sci Int (2013) 0.87

Nocturnal physiological and biochemical changes in sudden unexplained death syndrome: a preliminary report of a case control study. Southeast Asian J Trop Med Public Health (1994) 0.86

Identification of rare variants of DSP gene in sudden unexplained nocturnal death syndrome in the southern Chinese Han population. Int J Legal Med (2015) 0.85

A life-sustaining function for REM sleep: a theory. Neurosci Biobehav Rev (1986) 0.85

Postmortem genetic screening of SNPs in RyR2 gene in sudden unexplained nocturnal death syndrome in the southern Chinese Han population. Forensic Sci Int (2013) 0.85

The common African American polymorphism SCN5A-S1103Y interacts with mutation SCN5A-R680H to increase late Na current. Physiol Genomics (2011) 0.83

Molecular Autopsy of Desmosomal Protein Plakophilin-2 in Sudden Unexplained Nocturnal Death Syndrome. J Forensic Sci (2016) 0.81

A case-control study of sudden unexplained nocturnal death syndrome in the southern Chinese Han population. Am J Forensic Med Pathol (2015) 0.81

Forensic Pathological Study of 1656 Cases of Sudden Cardiac Death in Southern China. Medicine (Baltimore) (2016) 0.81

Triggers for arrhythmogenesis in the Brugada and long QT 3 syndromes. Prog Biophys Mol Biol (2015) 0.79

Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes. Nat Biotechnol (2011) 4.84

Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell (2004) 3.55

Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome. Circulation (2006) 3.50

Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing. Heart Rhythm (2004) 3.15

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex. Proc Natl Acad Sci U S A (2008) 2.79

Spontaneous coronary vasospasm in KATP mutant mice arises from a smooth muscle-extrinsic process. Circ Res (2006) 2.64

Increased late sodium current in myocytes from a canine heart failure model and from failing human heart. J Mol Cell Cardiol (2005) 2.60

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells. Nat Cell Biol (2012) 2.56

SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome. Circulation (2007) 2.42

Targeted mutational analysis of the RyR2-encoded cardiac ryanodine receptor in sudden unexplained death: a molecular autopsy of 49 medical examiner/coroner's cases. Mayo Clin Proc (2004) 2.40

Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation (2007) 2.33

Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62. J Biol Chem (2007) 2.23

Common human SCN5A polymorphisms have altered electrophysiology when expressed in Q1077 splice variants. Heart Rhythm (2005) 2.18

Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels. J Clin Invest (2002) 2.11

Enhanced detection of low abundance human plasma proteins using a tandem IgY12-SuperMix immunoaffinity separation strategy. Mol Cell Proteomics (2008) 2.08

An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. Immunity (2013) 1.98

Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell (2012) 1.98

A novel SCN5A arrhythmia mutation, M1766L, with expression defect rescued by mexiletine. Cardiovasc Res (2002) 1.96

Epinephrine reduces cerebral perfusion during cardiopulmonary resuscitation. Crit Care Med (2009) 1.91

Gain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromes. Heart Rhythm (2010) 1.89

Genotypic heterogeneity and phenotypic mimicry among unrelated patients referred for catecholaminergic polymorphic ventricular tachycardia genetic testing. Heart Rhythm (2006) 1.87

Autophagy contributes to leaf starch degradation. Plant Cell (2013) 1.85

A review of soil heavy metal pollution from mines in China: pollution and health risk assessment. Sci Total Environ (2013) 1.78

Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products. Cell Res (2010) 1.77

Epidemiologic, molecular, and functional evidence suggest A572D-SCN5A should not be considered an independent LQT3-susceptibility mutation. Heart Rhythm (2010) 1.76

Novel mechanism for sudden infant death syndrome: persistent late sodium current secondary to mutations in caveolin-3. Heart Rhythm (2006) 1.74

Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue-specific regulation for stress-inducible Hsp molecular chaperones. J Cell Biochem (2002) 1.73

Sudden infant death syndrome-associated mutations in the sodium channel beta subunits. Heart Rhythm (2010) 1.72

SLC11A1 (NRAMP1) polymorphisms and tuberculosis susceptibility: updated systematic review and meta-analysis. PLoS One (2011) 1.70

Elevated hyaluronan production induces mesenchymal and transformed properties in epithelial cells. J Biol Chem (2003) 1.66

A prospective clinical study of proximal humerus fractures treated with a locking proximal humerus plate. J Orthop Trauma (2011) 1.66

A novel C-terminal truncation SCN5A mutation from a patient with sick sinus syndrome, conduction disorder and ventricular tachycardia. Cardiovasc Res (2007) 1.64

Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome. Circulation (2007) 1.64

Analysis of spatial and temporal water pollution patterns in Lake Dianchi using multivariate statistical methods. Environ Monit Assess (2009) 1.62

Accelerated fat absorption in intestinal alkaline phosphatase knockout mice. Mol Cell Biol (2003) 1.60

MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer. Cancer Res (2009) 1.60

A common human SCN5A polymorphism modifies expression of an arrhythmia causing mutation. Physiol Genomics (2003) 1.56

Increases in tissue Pco2 during circulatory shock reflect selective decreases in capillary blood flow. Crit Care Med (2006) 1.54

Satellite-Based Spatiotemporal Trends in PM2.5 Concentrations: China, 2004-2013. Environ Health Perspect (2015) 1.51

KCNJ2 mutations in arrhythmia patients referred for LQT testing: a mutation T305A with novel effect on rectification properties. Heart Rhythm (2006) 1.51

Unique mixed phenotype and unexpected functional effect revealed by novel compound heterozygosity mutations involving SCN5A. Heart Rhythm (2009) 1.50

Inhaled fluticasone propionate by diskus in the treatment of asthma: a comparison of the efficacy of the same nominal dose given either once or twice a day. Chest (2003) 1.50

A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs. Cardiovasc Res (2004) 1.49

Structures of the spectrin-ankyrin interaction binding domains. Blood (2009) 1.49

ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy. EMBO Rep (2014) 1.49

SOAPfuse: an algorithm for identifying fusion transcripts from paired-end RNA-Seq data. Genome Biol (2013) 1.47

Argonaute 2 complexes selectively protect the circulating microRNAs in cell-secreted microvesicles. PLoS One (2012) 1.47

Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation. Proc Natl Acad Sci U S A (2011) 1.43

Fourth-generation plasma immersion ion implantation and deposition facility for hybrid surface modification layer fabrication. Rev Sci Instrum (2008) 1.43

Effect of airborne contaminants on the wettability of supported graphene and graphite. Nat Mater (2013) 1.42

Monodisperse porous LiFePO4 microspheres for a high power Li-ion battery cathode. J Am Chem Soc (2011) 1.41

Fast function-on-scalar regression with penalized basis expansions. Int J Biostat (2010) 1.41

Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection. J Virol (2002) 1.39

Letter to the editor: another treatment choice for subdural effusion with ventricle dilation. Acta Neurochir (Wien) (2015) 1.38

Anal HPV infection in HIV-positive men who have sex with men from China. PLoS One (2010) 1.37

The expression of the Alzheimer's amyloid precursor protein-like gene is regulated by developmental timing microRNAs and their targets in Caenorhabditis elegans. Dev Biol (2008) 1.36

Function and distribution of the SUR isoforms and splice variants. J Mol Cell Cardiol (2005) 1.35

Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein. Mol Cancer Res (2003) 1.34

Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy. Am J Physiol Gastrointest Liver Physiol (2008) 1.33

MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. J Biol Chem (2004) 1.33

Hierarchical Aligned Cluster Analysis for Temporal Clustering of Human Motion. IEEE Trans Pattern Anal Mach Intell (2012) 1.31

Community-based survey of HIV transmission modes among intravenous drug users in Sichuan, China. Sex Transm Dis (2004) 1.31

Hepatic transforming growth factor beta gives rise to tumor-initiating cells and promotes liver cancer development. Hepatology (2012) 1.30

The association of sport performance with ACE and ACTN3 genetic polymorphisms: a systematic review and meta-analysis. PLoS One (2013) 1.29

Physiologic control of IDO competence in splenic dendritic cells. J Immunol (2011) 1.29

MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling. Mol Cancer Res (2006) 1.27

Ideotype root architecture for efficient nitrogen acquisition by maize in intensive cropping systems. Sci China Life Sci (2010) 1.26

HIV incidence and factors contributed to retention in a 12-month follow-up study of injection drug users in Sichuan Province, China. J Acquir Immune Defic Syndr (2005) 1.26

Remediating organizational functioning in children with ADHD: immediate and long-term effects from a randomized controlled trial. J Consult Clin Psychol (2012) 1.25

Differential tissue-specific regulation of antiviral CD8+ T-cell immune responses during chronic viral infection. J Virol (2004) 1.24

Bioinspired catecholic chemistry for surface modification. Chem Soc Rev (2011) 1.24

Use-dependent block of cardiac late Na(+) current by ranolazine. Heart Rhythm (2009) 1.23

miR-143 is downregulated in cervical cancer and promotes apoptosis and inhibits tumor formation by targeting Bcl-2. Mol Med Rep (2011) 1.23

Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells. J Immunol (2005) 1.21

Increased dry-season length over southern Amazonia in recent decades and its implication for future climate projection. Proc Natl Acad Sci U S A (2013) 1.21

Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer. Bioorg Med Chem Lett (2011) 1.20

Individualized estimates of second cancer risks after contemporary radiation therapy for Hodgkin lymphoma. Cancer (2007) 1.20

A mutation in telethonin alters Nav1.5 function. J Biol Chem (2008) 1.20

Imbalanced intrahepatic cytokine expression of interferon-gamma, tumor necrosis factor-alpha, and interleukin-10 in patients with acute-on-chronic liver failure associated with hepatitis B virus infection. J Clin Gastroenterol (2009) 1.20

Prevalence of drug-resistant tuberculosis in mainland China: systematic review and meta-analysis. PLoS One (2011) 1.19

Estimating ground-level PM2.5 in China using satellite remote sensing. Environ Sci Technol (2014) 1.19

Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity. Dev Cell (2006) 1.19

Persistence of side population cells with high drug efflux capacity in pancreatic cancer. World J Gastroenterol (2008) 1.18

DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation. Cancer Res (2008) 1.17

Sudden unexplained nocturnal death syndrome in Southern China: an epidemiological survey and SCN5A gene screening. Am J Forensic Med Pathol (2011) 1.17

Cyclin G1-mediated epithelial-mesenchymal transition via phosphoinositide 3-kinase/Akt signaling facilitates liver cancer progression. Hepatology (2012) 1.17

Community-based survey of HCV and HIV coinfection in injection drug abusers in Sichuan Province of China. World J Gastroenterol (2004) 1.16

Amino acid catabolism: a pivotal regulator of innate and adaptive immunity. Immunol Rev (2012) 1.16

Continued spread of HIV among injecting drug users in southern Sichuan Province, China. Harm Reduct J (2007) 1.16

Meta-analysis: total parenteral nutrition versus total enteral nutrition in predicted severe acute pancreatitis. Intern Med (2012) 1.16

The quality of chest compressions during cardiopulmonary resuscitation overrides importance of timing of defibrillation. Chest (2007) 1.15

Lure similarity affects visual episodic recognition: detailed tests of a noisy exemplar model. Mem Cognit (2007) 1.14

HIV incidence, retention, and changes of high-risk behaviors among rural injection drug users in Guangxi, China. Subst Abus (2006) 1.14

Transdifferentiation of pulmonary arteriolar endothelial cells into smooth muscle-like cells regulated by myocardin involved in hypoxia-induced pulmonary vascular remodelling. Int J Exp Pathol (2006) 1.14

Genetic polymorphisms in pre-microRNA genes as prognostic markers of colorectal cancer. Cancer Epidemiol Biomarkers Prev (2011) 1.14

Ehd4 encodes a novel and Oryza-genus-specific regulator of photoperiodic flowering in rice. PLoS Genet (2013) 1.13

Mice lacking sulfonylurea receptor 2 (SUR2) ATP-sensitive potassium channels are resistant to acute cardiovascular stress. J Mol Cell Cardiol (2007) 1.13

GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis. Eur J Cancer (2011) 1.13

One-shock versus three-shock defibrillation protocol significantly improves outcome in a porcine model of prolonged ventricular fibrillation cardiac arrest. Circulation (2006) 1.12