Published in Nat Rev Cardiol on July 07, 2016
The Nutraceutical Dehydrozingerone and Its Dimer Counteract Inflammation- and Oxidative Stress-Induced Dysfunction of In Vitro Cultured Human Endothelial Cells: A Novel Perspective for the Prevention and Therapy of Atherosclerosis. Oxid Med Cell Longev (2016) 0.75
Date Palm Tree (Phoenix dactylifera L.): Natural Products and Therapeutic Options. Front Plant Sci (2017) 0.75
Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med (2013) 20.98
Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. N Engl J Med (2015) 13.90
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet (2007) 9.56
Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis. JAMA (2012) 9.37
Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet (1989) 9.27
Bioavailability of curcumin: problems and promises. Mol Pharm (2007) 8.72
Impact of Dual Lipid-Lowering Strategy With Ezetimibe and Atorvastatin on Coronary Plaque Regression in Patients With Percutaneous Coronary Intervention: The Multicenter Randomized Controlled PRECISE-IVUS Trial. J Am Coll Cardiol (2015) 7.57
MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet (2002) 7.41
Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev (2001) 7.19
Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) Lancet (1996) 6.48
Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: a meta-analysis of randomized, double-blind, placebo-controlled trials. Arch Intern Med (2012) 5.84
Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med (2000) 5.09
Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. Physiol Rev (2012) 4.52
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med (2004) 3.92
Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review. BMJ (2006) 3.47
Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation. FASEB J (2006) 3.37
Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids. Nutr Rev (2010) 3.30
The effect of polyphenols in olive oil on heart disease risk factors: a randomized trial. Ann Intern Med (2006) 3.05
Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr (2000) 2.92
Omega-3 polyunsaturated fatty acids and cardiovascular diseases. J Am Coll Cardiol (2009) 2.83
Omega-3 fatty acids for cardioprotection. Mayo Clin Proc (2008) 2.65
Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studies. Arch Intern Med (2004) 2.60
Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels. Mayo Clin Proc (2003) 2.56
Effect of statins on skeletal muscle function. Circulation (2012) 2.54
Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans. J Hypertens (2003) 2.54
Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2005) 2.42
Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial. Arch Intern Med (2007) 2.29
Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation (1996) 2.28
Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). BMJ (2016) 2.17
Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. Cardiovasc Res (2005) 2.15
Berberine suppresses proinflammatory responses through AMPK activation in macrophages. Am J Physiol Endocrinol Metab (2009) 2.14
Intake of fish and n3 fatty acids and risk of coronary heart disease among Japanese: the Japan Public Health Center-Based (JPHC) Study Cohort I. Circulation (2006) 2.12
A prospective study of dietary fiber intake and risk of cardiovascular disease among women. J Am Coll Cardiol (2002) 2.10
Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain. Proc Natl Acad Sci U S A (1988) 2.04
Carbohydrate intake, glycemic index, glycemic load, and dietary fiber in relation to risk of stroke in women. Am J Epidemiol (2005) 2.03
Garlic shows promise for improving some cardiovascular risk factors. Arch Intern Med (2001) 1.99
Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS). Circulation (2002) 1.99
Importance of the ratio of omega-6/omega-3 essential fatty acids: evolutionary aspects. World Rev Nutr Diet (2003) 1.98
Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease. Atherosclerosis (2013) 1.88
Coronary risk factors, endothelial function, and atherosclerosis: a review. Clin Cardiol (1997) 1.86
Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression. Am J Clin Nutr (2010) 1.85
Endogenously decreasing tissue n-6/n-3 fatty acid ratio reduces atherosclerotic lesions in apolipoprotein E-deficient mice by inhibiting systemic and vascular inflammation. Arterioscler Thromb Vasc Biol (2010) 1.85
Flavonoids: biosynthesis, biological functions, and biotechnological applications. Front Plant Sci (2012) 1.84
Health benefits of fruits and vegetables. Adv Nutr (2012) 1.77
Antioxidant vitamin supplements and cardiovascular disease. Circulation (2004) 1.76
Antioxidant vitamin C improves endothelial dysfunction in chronic smokers. Circulation (1996) 1.67
Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine. J Biol Chem (2009) 1.67
Orally administered eicosapentaenoic acid induces rapid regression of atherosclerosis via modulating the phenotype of dendritic cells in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol (2011) 1.66
Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol (2003) 1.65
Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol Res (1999) 1.62
Cardiovascular effects of flavanol-rich chocolate in patients with heart failure. Eur Heart J (2011) 1.59
Green tea catechins and cardiovascular health: an update. Curr Med Chem (2008) 1.58
Coenzyme Q10 supplementation ameliorates inflammatory markers in patients with multiple sclerosis: a double blind, placebo, controlled randomized clinical trial. Nutr Neurosci (2014) 1.57
Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity. Circ Res (2003) 1.54
Beneficial effects of polyphenol-rich olive oil in patients with early atherosclerosis. Eur J Nutr (2012) 1.51
Interferon gamma: a master regulator of atherosclerosis. Cytokine Growth Factor Rev (2008) 1.50
The antiatherosclerotic effect of Allium sativum. Atherosclerosis (1999) 1.49
Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study. J Clin Pharmacol (1993) 1.45
Effects of docosahexaenoic Acid on the endothelial function in patients with coronary artery disease. J Atheroscler Thromb (2014) 1.45
Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy. Prog Lipid Res (2011) 1.40
Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler Thromb Vasc Biol (2003) 1.39
Supplementation with vitamins C and E improves arterial stiffness and endothelial function in essential hypertensive patients. Am J Hypertens (2007) 1.36
Atherosclerosis and extracellular matrix. J Atheroscler Thromb (2003) 1.35
Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Am J Clin Nutr (2004) 1.35
Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis. Atherosclerosis (1999) 1.32
Plasma sitosterol elevations are associated with an increased incidence of coronary events in men: results of a nested case-control analysis of the Prospective Cardiovascular Münster (PROCAM) study. Nutr Metab Cardiovasc Dis (2005) 1.30
Role of antioxidant lycopene in cancer and heart disease. J Am Coll Nutr (2000) 1.27
Hydroxytyrosol: from laboratory investigations to future clinical trials. Nutr Rev (2010) 1.26
Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules. Lipids Health Dis (2008) 1.26
Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: a potentially protective mechanism in atherosclerotic vascular disease and cancer. Arch Biochem Biophys (2012) 1.24
Independent association of serum squalene and noncholesterol sterols with coronary artery disease in postmenopausal women. J Am Coll Cardiol (2000) 1.22
From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection. Circ Res (2016) 1.22
Lycopene and cardiovascular disease. Am J Clin Nutr (2000) 1.18
Relation of plaque lipid composition and morphology to the stability of human aortic plaques. Arterioscler Thromb Vasc Biol (1997) 1.16
Exogenous hydrogen sulfide inhibits superoxide formation, NOX-1 expression and Rac1 activity in human vascular smooth muscle cells. J Vasc Res (2008) 1.15
Food consumption patterns in the 1960s in seven countries. Am J Clin Nutr (1989) 1.15
Hydrogen sulfide prevents apoptosis of human PMN via inhibition of p38 and caspase 3. Lab Invest (2006) 1.14
Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study. Nutr Metab Cardiovasc Dis (2009) 1.14
Dietary fish oil reduces intercellular adhesion molecule 1 and scavenger receptor expression on murine macrophages. Atherosclerosis (2000) 1.11
Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2. PLoS One (2011) 1.10
Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3-year progression of carotid atherosclerosis. J Intern Med (2000) 1.10
Polyunsaturated fatty acids in the food chain in Europe. Am J Clin Nutr (2000) 1.09
Effects of oral lycopene supplementation on vascular function in patients with cardiovascular disease and healthy volunteers: a randomised controlled trial. PLoS One (2014) 1.09
Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits. Arterioscler Thromb Vasc Biol (2002) 1.09
Combination of simvastatin with berberine improves the lipid-lowering efficacy. Metabolism (2008) 1.08
Plasma concentrations of plant sterols: physiology and relationship with coronary heart disease. Nutr Rev (2006) 1.08
Statins in the treatment of dyslipidemia in the presence of elevated liver aminotransferase levels: a therapeutic dilemma. Mayo Clin Proc (2010) 1.06
Effect of curcumin on atherosclerosis in apoE/LDLR-double knockout mice. J Physiol Pharmacol (2005) 1.06
Coronary heart disease in seven countries. 1970. Nutrition (1997) 1.04
Hydrogen sulfide inhibits macrophage-derived foam cell formation. Exp Biol Med (Maywood) (2011) 1.04
[Coronary risk factors. The French paradox]. Arch Mal Coeur Vaiss (1987) 1.04
One-month administration of hydroxytyrosol, a phenolic antioxidant present in olive oil, to hyperlipemic rabbits improves blood lipid profile, antioxidant status and reduces atherosclerosis development. Atherosclerosis (2005) 1.03
Chronic green tea extract supplementation reduces hemodialysis-enhanced production of hydrogen peroxide and hypochlorous acid, atherosclerotic factors, and proinflammatory cytokines. Am J Clin Nutr (2007) 1.03
Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. Biochem Biophys Res Commun (1997) 1.02
Berberine inhibits adipogenesis in high-fat diet-induced obesity mice. Fitoterapia (2009) 1.00
Intake of dietary plant sterols is inversely related to serum cholesterol concentration in men and women in the EPIC Norfolk population: a cross-sectional study. Eur J Clin Nutr (2004) 1.00