What is New in Acute Pancreatitis?

Early antibiotic treatment in acute necrotising pancreatitis. Lancet (1995) 4.86

Prophylactic antibiotic treatment in patients with predicted severe acute pancreatitis: a placebo-controlled, double-blind trial. Gastroenterology (2004) 4.24

Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest (2000) 3.47

Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: a multicentre study. Lancet (2000) 3.16

Meta-analysis of parenteral nutrition versus enteral nutrition in patients with acute pancreatitis. BMJ (2004) 2.96

Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis. Gastroenterology (1997) 2.84

Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis. Br J Surg (2002) 2.72

Management of the critically ill patient with severe acute pancreatitis. Crit Care Med (2004) 2.16

Persistent organ failure during the first week as a marker of fatal outcome in acute pancreatitis. Gut (2004) 2.12

Multicentre comparative study of two schedules of gabexate mesilate in the treatment of acute pancreatitis. Italian Acute Pancreatitis Study Group. Dig Liver Dis (2001) 1.99

A randomised clinical trial to assess the effect of total enteral and total parenteral nutritional support on metabolic, inflammatory and oxidative markers in patients with predicted severe acute pancreatitis (APACHE II > or =6). Pancreatology (2003) 1.85

Percutaneous necrosectomy and sinus tract endoscopy in the management of infected pancreatic necrosis: an initial experience. Ann Surg (2000) 1.75

Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis. Gut (2001) 1.68

Procalcitonin strip test in the early detection of severe acute pancreatitis. Br J Surg (2001) 1.68

Intravenous bolus somatostatin after diagnostic cholangiopancreatography reduces the incidence of pancreatitis associated with therapeutic endoscopic retrograde cholangiopancreatography procedures: a randomised controlled trial. Gut (2003) 1.66

Blood concentrations of polymorphonuclear leucocyte elastase and interleukin-6 are indicators for the occurrence of multiple organ failures at the early stage of acute pancreatitis. J Gastroenterol Hepatol (1998) 1.63

Pancreatic infection in severe pancreatitis: the role of fungus and multiresistant organisms. Arch Surg (2001) 1.31

Prophylactic antibiotics in treatment of severe acute alcoholic pancreatitis. Pancreas (1996) 1.25

Retroperitoneal approach and endoscopic management of peripancreatic necrosis collections. Arch Surg (1998) 1.24

A technique for laparoscopic-assisted percutaneous drainage of infected pancreatic necrosis and pancreatic abscess. Surg Endosc (2001) 1.20

Genetic testing for hereditary pancreatitis: guidelines for indications, counselling, consent and privacy issues. Pancreatology (2001) 1.17

Signal transduction, calcium and acute pancreatitis. Pancreatology (2003) 1.12

Prognostic factors in acute pancreatitis. J Clin Gastroenterol (2002) 1.11

Appropriate timing of cholecystectomy in patients who present with moderate to severe gallstone-associated acute pancreatitis with peripancreatic fluid collections. Ann Surg (2004) 1.06

Early treatment with antibiotics reduces the need for surgery in acute necrotizing pancreatitis--a single-center randomized study. J Gastrointest Surg (2001) 1.05

Value of genetic testing in the management of pancreatitis. Gut (2004) 1.05

Improved prediction of outcome in patients with severe acute pancreatitis by the APACHE II score at 48 hours after hospital admission compared with the APACHE II score at admission. Acute Physiology and Chronic Health Evaluation. Arch Surg (2002) 1.00

Effect of glutamine-enriched total parenteral nutrition in patients with acute pancreatitis. Clin Nutr (2002) 0.98

Simultaneous serum assays of lipase and interleukin-6 for early diagnosis and prognosis of acute pancreatitis. Clin Chem (1999) 0.96

Early debridement for necrotizing pancreatitis: is it worthwhile? J Am Coll Surg (2002) 0.91

Clinical study on nutrition support in patients with severe acute pancreatitis. World J Gastroenterol (2003) 0.89

Early events in acute pancreatitis. Gastroenterol Clin North Am (2004) 0.88

Early jejunal nutrition and changes in the immunological parameters of patients with acute pancreatitis. Hepatogastroenterology (2001) 0.85

Urinary trypsinogen activation peptide as a marker of severe acute pancreatitis. Br J Surg (2004) 0.83

Cationic trypsinogen mutations and pancreatitis. Gastroenterol Clin North Am (2004) 0.81

Predictors of severity and necrosis in acute pancreatitis. Gastroenterol Clin North Am (2004) 0.80

Early physiological response to intensive care as a clinically relevant approach to predicting the outcome in severe acute pancreatitis. Arch Surg (2004) 0.79

Plasma trypsinogen activation peptide in patients with acute pancreatitis. Br J Surg (2001) 0.78