Published in Oncotarget on September 13, 2016
Cancer statistics, 2015. CA Cancer J Clin (2015) 57.51
Natural products as sources of new drugs over the 30 years from 1981 to 2010. J Nat Prod (2012) 13.27
Protein modification by SUMO. Annu Rev Biochem (2004) 10.59
SUMO: a history of modification. Mol Cell (2005) 10.40
SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell (2007) 4.46
SUMOylation and De-SUMOylation: wrestling with life's processes. J Biol Chem (2008) 3.22
Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay. Science (2013) 2.74
Role of desumoylation in the development of prostate cancer. Neoplasia (2006) 1.90
Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis. Cancer Detect Prev (2004) 1.60
Ki67 immunohistochemistry: a valuable marker in prognostication but with a risk of misclassification: proliferation subgroups formed based on Ki67 immunoreactivity and standardized mitotic index. Histopathology (2006) 1.52
Genetic and proteomic evidence for roles of Drosophila SUMO in cell cycle control, Ras signaling, and early pattern formation. PLoS One (2009) 1.48
Induction of the SUMO-specific protease 1 transcription by the androgen receptor in prostate cancer cells. J Biol Chem (2007) 1.41
SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms. J Biol Chem (2010) 1.29
NAC-1, a potential stem cell pluripotency factor, contributes to paclitaxel resistance in ovarian cancer through inactivating Gadd45 pathway. Oncogene (2009) 1.18
SUMO-specific protease 1 promotes prostate cancer progression and metastasis. Oncogene (2012) 1.16
SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors. Cancer Lett (2011) 1.10
Progression of metastatic castrate-resistant prostate cancer: impact of therapeutic intervention in the post-docetaxel space. J Hematol Oncol (2011) 1.05
Triptolide inhibits the proliferation of prostate cancer cells and down-regulates SUMO-specific protease 1 expression. PLoS One (2012) 1.02
Transition zone PSA density improves the prostate cancer detection rate both in PSA 4.0-10.0 and 10.1-20.0 ng/ml in Chinese men. Urol Oncol (2011) 1.01
Important role of SUMOylation of Spliceosome factors in prostate cancer cells. J Proteome Res (2014) 0.99
Biological role and prognostic significance of NAC1 in ovarian cancer. Gynecol Oncol (2010) 0.99
Biological and clinical significance of NAC1 expression in cervical carcinomas: a comparative study between squamous cell carcinomas and adenocarcinomas/adenosquamous carcinomas. Hum Pathol (2011) 0.96
Structure-related inhibitory activity of oleanolic acid glycosides on gastric emptying in mice. Bioorg Med Chem (1999) 0.95
Intrinsic apoptotic pathway and G2/M cell cycle arrest involved in tubeimoside I-induced EC109 cell death. Chin J Cancer Res (2013) 0.87
SUMO-specific protease 1 regulates pancreatic cancer cell proliferation and invasion by targeting MMP-9. Tumour Biol (2014) 0.87
Identification and characterization of a new chemotype of noncovalent SENP inhibitors. ACS Chem Biol (2013) 0.87
Momordin Ic induces HepG2 cell apoptosis through MAPK and PI3K/Akt-mediated mitochondrial pathways. Apoptosis (2013) 0.86
Antiproliferative effects of saponins from the roots of Platycodon grandiflorum on cultured human tumor cells. J Nat Prod (2010) 0.84
Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitors. Bioorg Med Chem Lett (2012) 0.83
Momordin Ic and oleanolic acid from Kochiae Fructus reduce carbon tetrachloride-induced hepatotoxicity in rats. J Med Food (2005) 0.83
TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol. J Pharmacol Sci (2014) 0.80
Triterpenoid glycosides from the fruits of Kochia scoparia. Planta Med (1995) 0.79
Effects of oleanolic acid glycosides on gastrointestinal transit and ileus in mice. Bioorg Med Chem (1999) 0.78
Proton pump inhibitors enhance the effects of cytotoxic agents in chemoresistant epithelial ovarian carcinoma. Oncotarget (2015) 0.77
A novel mechanism for momordin Ic-induced HepG2 apoptosis: involvement of PI3K- and MAPK-dependent PPARγ activation. Food Funct (2014) 0.77
Sentrin/small ubiquitin-like modifier-specific protease 5 protects oral cancer cells from oxidative stress-induced apoptosis. Mol Med Rep (2015) 0.77
Acceleration of gastrointestinal transit by momordin Ic in mice: possible involvement of 5-hydroxytryptamine, 5-HT(2) receptors and prostaglandins. Eur J Pharmacol (2000) 0.77
CDDO-Me reveals USP7 as a novel target in ovarian cancer cells. Oncotarget (2016) 0.81