Interferon gamma-induced apoptosis of head and neck squamous cell carcinoma is connected to indoleamine-2,3-dioxygenase via mitochondrial and ER stress-associated pathways.

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Published in Cell Div on August 02, 2016

Authors

Siraj M El Jamal1, Erin B Taylor2, Zakaria Y Abd Elmageed3, Abdulhadi A Alamodi2, Denis Selimovic4, Abdulaziz Alkhateeb5, Matthias Hannig6, Sofie Y Hassan7, Simeon Santourlidis8, Paul L Friedlander3, Youssef Haikel9, Srinivasan Vijaykumar10, Emad Kandil3, Mohamed Hassan11

Author Affiliations

1: Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216 USA.
2: Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216 USA.
3: Departments of Surgery, Tulane University School of Medicine, New Orleans, LA 70112 USA.
4: Clinic of Operative Dentistry, Periodontology and Preventive Dentistry, Saarland University, Kirrberger Str. 100, 66421 Homburg/Saar, Germany ; Division of Oral Health Science, Department of Restorative Dentistry, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
5: Clinic of Dermatology, University Hospital of Aachen, Puwelstrasse 30, Aachen, Germany ; College of Medicine, King Faisal University, Alhofuf, Saudi Arabia.
6: Clinic of Operative Dentistry, Periodontology and Preventive Dentistry, Saarland University, Kirrberger Str. 100, 66421 Homburg/Saar, Germany.
7: Clinic of Dermatology, University Hospital of Aachen, Puwelstrasse 30, Aachen, Germany.
8: Epigenetics Core Laboratory, Institute of Transplantation Diagnostics and Cell Therapeutics, University Hospital of Duesseldorf, Heinrich-Heine-University of Duesseldorf, Mooren Str.5, 40225 Duesseldorf, Germany.
9: Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 67000 Strasbourg, France ; Department of Operative Dentistry and Endodontics, Dental Faculty, University of Strasbourg, 67000 Strasbourg, France.
10: Department of Radiation Oncology, University of Mississippi Medical Center, Jackson, MS 39216 USA ; Cancer Institute, University of Mississippi Medical Center, Jackson, MS 39216 USA.
11: Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216 USA ; Clinic of Operative Dentistry, Periodontology and Preventive Dentistry, Saarland University, Kirrberger Str. 100, 66421 Homburg/Saar, Germany ; Institut National de la Santé et de la Recherche Médicale, University of Strasbourg, 67000 Strasbourg, France ; Cancer Institute, University of Mississippi Medical Center, Jackson, MS 39216 USA.

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