Published in PLoS One on August 17, 2016
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. Cell (2004) 16.15
Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division. Cancer Res (1973) 7.59
Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell (1979) 6.47
TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN. J Exp Med (1925) 6.38
Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000. Environ Health Perspect (2004) 5.32
Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet (1999) 5.31
Inhibition of histone deacetylase activity by butyrate. J Nutr (2003) 3.84
Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell (1991) 3.71
Gene expression regulation by retinoic acid. J Lipid Res (2002) 3.62
Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression. Cell (1991) 3.53
The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol Sci (2000) 3.46
Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat. Toxicol Sci (2000) 3.45
Retinoic acid in development: towards an integrated view. Nat Rev Genet (2008) 3.24
An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am J Anat (1953) 2.76
P19 embryonal carcinoma cells. Int J Dev Biol (1993) 2.71
Disruption of reproductive development in male rat offspring following in utero exposure to phthalate esters. Int J Androl (2005) 2.48
Identification of phthalates in medications and dietary supplement formulations in the United States and Canada. Environ Health Perspect (2011) 2.40
Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development. Mech Dev (1997) 2.26
Retinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterning. Curr Biol (2009) 2.22
Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestation. Toxicol Sci (2000) 2.19
Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development. Nat Genet (2005) 1.98
Hox genes and segmentation of the hindbrain and axial skeleton. Annu Rev Cell Dev Biol (2009) 1.96
Physiological insights into all-trans-retinoic acid biosynthesis. Biochim Biophys Acta (2011) 1.86
Vitamin A in reproduction and development. Nutrients (2011) 1.70
Aetiology of hypospadias: a systematic review of genes and environment. Hum Reprod Update (2012) 1.52
Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis. Proc Natl Acad Sci U S A (2012) 1.29
Nuclear hormone receptor co-repressors: structure and function. Mol Cell Endocrinol (2011) 1.23
Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia. Development (2005) 1.22
The clinical spectrum of homozygous HOXA1 mutations. Am J Med Genet A (2008) 1.16
Mode of action: impaired fetal leydig cell function--effects on male reproductive development produced by certain phthalate esters. Crit Rev Toxicol (2006) 1.16
Malformations in the genito-urinary tract induced by maternal vitamin A deficiency in the rat. Am J Anat (1948) 1.09
Testicular descent: INSL3, testosterone, genes and the intrauterine milieu. Nat Rev Urol (2011) 1.07
Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation. Dev Dyn (2007) 1.05
The role of sonic hedgehog-Gli2 pathway in the masculinization of external genitalia. Endocrinology (2011) 1.03
Phthalates and diet: a review of the food monitoring and epidemiology data. Environ Health (2014) 1.02
Control of mammalian germ cell entry into meiosis. Mol Cell Endocrinol (2013) 1.01
Thermodynamic parameters of the binding of retinol to binding proteins and to membranes. Biochemistry (1990) 0.97
RDH10 is the primary enzyme responsible for the first step of embryonic Vitamin A metabolism and retinoic acid synthesis. Dev Biol (2011) 0.95
Dipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates. Toxicol Sci (2010) 0.93
A nutritional model of late embryonic vitamin A deficiency produces defects in organogenesis at a high penetrance and reveals new roles for the vitamin in skeletal development. Dev Biol (2007) 0.90
Medications as a potential source of exposure to phthalates among women of childbearing age. Reprod Toxicol (2013) 0.89
An evolving understanding of nuclear receptor coregulator proteins. J Mol Endocrinol (2013) 0.89
Vitamin A deficiency in the late gastrula stage rat embryo results in a one to two vertebral anteriorization that extends throughout the axial skeleton. Dev Biol (2003) 0.86
External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium. Ann N Y Acad Sci (2001) 0.86
Diisobutyl phthalate impairs the androgen-dependent reproductive development of the male rat. Reprod Toxicol (2008) 0.86
International geographic correlation study of the prevalence of disorders of male reproductive health. Hum Reprod (2013) 0.83
Retinoic acid promotes Sertoli cell differentiation and antagonises activin-induced proliferation. Mol Cell Endocrinol (2013) 0.83
The retinol signaling pathway in mouse pluripotent P19 cells. J Cell Biochem (2011) 0.82
INSL3 in the benign hyperplastic and neoplastic human prostate gland. Int J Oncol (2005) 0.82
Retinoic acid signaling regulates sonic hedgehog and bone morphogenetic protein signalings during genital tubercle development. Birth Defects Res B Dev Reprod Toxicol (2011) 0.81
Effects of in utero through lactational exposure to dicyclohexyl phthalate and p,p'-DDE in Sprague-Dawley rats. Toxicol Lett (2009) 0.80
A screen for disruptors of the retinol (vitamin A) signaling pathway. Birth Defects Res B Dev Reprod Toxicol (2013) 0.80
Retinoic acid biosynthesis is impaired in human and murine endometriosis. Biol Reprod (2014) 0.80
Control of alkaline phosphatase activity in C3H10T1/2 cells: role of retinoic acid and cell density. J Cell Physiol (1992) 0.78
Developmental effects of di-n-butyl phthalate after a single administration in rats. J Appl Toxicol (1997) 0.76