Published in J Virol on September 07, 2016
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Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia. Dev Cell (2007) 1.54
The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway. J Virol (2002) 1.54
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Antigenic structure of envelope glycoprotein E1 of hog cholera virus. J Virol (1994) 1.12
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Evaluation of a multiplex real-time RT-PCR for quantitative and differential detection of wild-type viruses and C-strain vaccine of Classical swine fever virus. Vet Microbiol (2007) 1.03
MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues. Cell Growth Differ (1993) 1.01
MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments. FASEB J (2007) 0.98
Generation and efficacy evaluation of a recombinant adenovirus expressing the E2 protein of classical swine fever virus. Res Vet Sci (2009) 0.98
Antigenic comparisons of hog cholera virus isolates from Europe, America and Asia using monoclonal antibodies. Dtsch Tierarztl Wochenschr (1990) 0.97
Virus-induced Ca2+ influx extends survival of west nile virus-infected cells. J Virol (2010) 0.97
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Molecular characterization of hog cholera virus. Arch Virol Suppl (1991) 0.93
Up-regulation of ERK and p38 MAPK signaling pathways by hepatitis C virus E2 envelope protein in human T lymphoma cell line. J Leukoc Biol (2006) 0.91
Activation of the Ras/Raf/MEK pathway facilitates hepatitis C virus replication via attenuation of the interferon-JAK-STAT pathway. J Virol (2011) 0.90
A novel MEK2/PI3Kδ pathway controls the expression of IL-1 receptor antagonist in IFN-β-activated human monocytes. J Leukoc Biol (2010) 0.90
Mitogen-activated protein kinase signalling pathways triggered by the hepatitis C virus envelope protein E2: implications for the prevention of infection. Cell Prolif (2007) 0.88
Porcine circovirus type 2 replication is impaired by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway. Virology (2009) 0.88
MEK1-ERKs signal cascade is required for the replication of Enterovirus 71 (EV71). Antiviral Res (2011) 0.88
Porcine reproductive and respiratory syndrome virus replication is suppressed by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway. Virus Res (2010) 0.85
Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2. Virus Res (2010) 0.84
Suppression of astrovirus replication by an ERK1/2 inhibitor. J Virol (2008) 0.83
Hemoglobin subunit beta interacts with the capsid protein and antagonizes the growth of classical swine fever virus. J Virol (2013) 0.82
Inhibition of dengue virus replication by a class of small-molecule compounds that antagonize dopamine receptor d4 and downstream mitogen-activated protein kinase signaling. J Virol (2014) 0.82
Annexin 2 is a host protein binding to classical swine fever virus E2 glycoprotein and promoting viral growth in PK-15 cells. Virus Res (2015) 0.82
Both ERK1 and ERK2 are required for enterovirus 71 (EV71) efficient replication. Viruses (2015) 0.81
MEK1 and MEK2 isoforms regulate distinct functions in pancreatic cancer cells. Oncol Rep (2010) 0.78
Thioredoxin 2 Is a Novel E2-Interacting Protein That Inhibits the Replication of Classical Swine Fever Virus. J Virol (2015) 0.78
Bile acids promote HCV replication through the EGFR/ERK pathway in replicon-harboring cells. Intervirology (2011) 0.78
Beta-actin interacts with the E2 protein and is involved in the early replication of classical swine fever virus. Virus Res (2013) 0.78
Cardiofaciocutaneous syndrome in a mother and two sons with a MEK2 mutation. Clin Dysmorphol (2011) 0.77