ROCS-derived features for virtual screening.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27624668)

Published in J Comput Aided Mol Des on September 08, 2016

Authors

Steven Kearnes1,2, Vijay Pande3

Author Affiliations

1: Stanford University, 318 Campus Dr. S296, Stanford, CA, 94305, USA. kearnes@stanford.edu.
2: Google Inc., 1600 Amphitheatre Pkwy, Mountain View, CA, 94043, USA. kearnes@stanford.edu.
3: Stanford University, 318 Campus Dr. S296, Stanford, CA, 94305, USA.

Articles cited by this

ChEMBL: a large-scale bioactivity database for drug discovery. Nucleic Acids Res (2011) 14.51

Random forest: a classification and regression tool for compound classification and QSAR modeling. J Chem Inf Comput Sci (2003) 5.93

Conformer generation with OMEGA: algorithm and validation using high quality structures from the Protein Databank and Cambridge Structural Database. J Chem Inf Model (2010) 4.38

Comparison of shape-matching and docking as virtual screening tools. J Med Chem (2007) 3.09

Directory of useful decoys, enhanced (DUD-E): better ligands and decoys for better benchmarking. J Med Chem (2012) 2.86

Recommendations for evaluation of computational methods. J Comput Aided Mol Des (2008) 1.87

Ultrafast shape recognition to search compound databases for similar molecular shapes. J Comput Chem (2007) 1.84

Community benchmarks for virtual screening. J Comput Aided Mol Des (2008) 1.49

Maximum unbiased validation (MUV) data sets for virtual screening based on PubChem bioactivity data. J Chem Inf Model (2009) 1.46

Scaffold hopping. Drug Discov Today Technol (2004) 1.24

Open-source platform to benchmark fingerprints for ligand-based virtual screening. J Cheminform (2013) 1.10

The use of three-dimensional shape and electrostatic similarity searching in the identification of a melanin-concentrating hormone receptor 1 antagonist. Chem Biol Drug Des (2006) 1.06

Heterogeneous classifier fusion for ligand-based virtual screening: or, how decision making by committee can be a good thing. J Chem Inf Model (2013) 0.91

Do not hesitate to use Tversky-and other hints for successful active analogue searches with feature count descriptors. J Chem Inf Model (2013) 0.83

Combination Rules for Group Fusion in Similarity-Based Virtual Screening. Mol Inform (2010) 0.82

Application of support vector machine to three-dimensional shape-based virtual screening using comprehensive three-dimensional molecular shape overlay with known inhibitors. J Chem Inf Model (2012) 0.80

Articles by these authors

Molecular graph convolutions: moving beyond fingerprints. J Comput Aided Mol Des (2016) 0.94