Published in Sci Rep on September 15, 2016
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. Sci Transl Med (2012) 8.04
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature (1998) 7.81
Copper biochemistry and molecular biology. Am J Clin Nutr (1996) 2.85
Neuroscience. Garbage truck of the brain. Science (2013) 1.97
Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes. J Med Genet (2007) 1.66
Menkes disease. Eur J Hum Genet (2009) 1.65
Menkes disease: a biochemical abnormality in cultured human fibroblasts. Proc Natl Acad Sci U S A (1976) 1.60
Copper-histidine therapy for Menkes disease. J Pediatr (1993) 1.56
Wilson's disease and other neurological copper disorders. Lancet Neurol (2015) 1.53
Human copper transporters: mechanism, role in human diseases and therapeutic potential. Future Med Chem (2009) 1.49
Copper metabolism in mottled mouse mutants: copper concentrations in tissues during development. Biochem J (1979) 1.42
An overview and update of ATP7A mutations leading to Menkes disease and occipital horn syndrome. Hum Mutat (2013) 1.32
ATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease mouse model. Mol Ther (2011) 1.19
Copper. J Toxicol Clin Toxicol (1999) 1.18
The Menkes protein (ATP7A; MNK) cycles via the plasma membrane both in basal and elevated extracellular copper using a C-terminal di-leucine endocytic signal. Hum Mol Genet (1999) 1.14
Treatment of Wilson and menkes diseases. Chem Rev (1999) 1.13
NKT cells in the rat: organ-specific distribution of NK T cells expressing distinct V alpha 14 chains. J Immunol (2000) 0.97
Inherited copper transport disorders: biochemical mechanisms, diagnosis, and treatment. Curr Drug Metab (2012) 0.90
Neurodevelopment and brain growth in classic Menkes disease is influenced by age and symptomatology at initiation of copper treatment. J Trace Elem Med Biol (2014) 0.82
An unusual neurological disorder of copper metabolism clinically resembling Wilson's disease but biochemically a distinct entity. J Neurol Sci (1978) 0.79
The relationship of excess copper accumulation by fibroblasts from the brindled mouse model of Menkes disease to the primary defect. Biochem J (1990) 0.79
Cellular mechanisms of toxicity and tolerance in the copper-loaded rat. III. Ultrastructural changes and copper localization in the kidney. Br J Exp Pathol (1989) 0.78