Published in Early Hum Dev on September 17, 2016
IGF-1/IGFBP3 Prevention of Retinopathy of Prematurity | NCT01096784
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med (1994) 16.24
The contribution of low birth weight to infant mortality and childhood morbidity. N Engl J Med (1985) 12.23
Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci (1994) 10.46
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell (1993) 10.36
Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol (2009) 6.90
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J (1986) 6.62
Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev (2002) 6.43
Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci U S A (1995) 5.92
Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci U S A (1995) 5.66
Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestation. Arch Dis Child Fetal Neonatal Ed (2001) 4.38
Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy. N Engl J Med (2005) 4.32
Characteristics of infants with severe retinopathy of prematurity in countries with low, moderate, and high levels of development: implications for screening programs. Pediatrics (2005) 3.97
Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev (1995) 3.58
Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity. Arch Ophthalmol (1996) 3.49
IGF-I is required for normal embryonic growth in mice. Genes Dev (1993) 3.17
Insights into advanced retinopathy of prematurity using handheld spectral domain optical coherence tomography imaging. Ophthalmology (2009) 2.99
Annual summary of vital statistics: 2007. Pediatrics (2009) 2.91
Postnatal serum insulin-like growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth. Pediatrics (2003) 2.85
The incidence and course of retinopathy of prematurity: findings from the early treatment for retinopathy of prematurity study. Pediatrics (2005) 2.65
Final results of the Early Treatment for Retinopathy of Prematurity (ETROP) randomized trial. Trans Am Ophthalmol Soc (2004) 2.55
Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity. Proc Natl Acad Sci U S A (2001) 2.35
Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism. PLoS Biol (2008) 2.35
Effects of oxygen on the development and severity of retinopathy of prematurity. J AAPOS (2013) 2.24
Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons. Neuron (1995) 2.19
Multicenter trial of cryotherapy for retinopathy of prematurity. Three-month outcome. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol (1990) 2.14
Essential role of growth hormone in ischemia-induced retinal neovascularization. Science (1997) 2.11
Foveal fine structure in retinopathy of prematurity: an adaptive optics Fourier domain optical coherence tomography study. Invest Ophthalmol Vis Sci (2008) 2.10
Further observations on cost of preventing retrolental fibroplasia. Lancet (1974) 2.02
Postnatal head growth deficit among premature infants parallels retinopathy of prematurity and insulin-like growth factor-1 deficit. Pediatrics (2006) 1.85
Achieved versus intended pulse oximeter saturation in infants born less than 28 weeks' gestation: the AVIOx study. Pediatrics (2006) 1.83
Unraveling insulin-like growth factor binding protein-3 actions in human disease. Endocr Rev (2009) 1.76
Recovery from retinopathy in a case of diabetes with Simmonds' disease. Diabetes (1953) 1.76
Recent increase in mortality from hyaline membrane disease. J Pediatr (1960) 1.76
Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development. J Neurosci (2000) 1.68
Multicenter trial of cryotherapy for retinopathy of prematurity. One-year outcome--structure and function. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol (1990) 1.63
Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity. Diabetes (2001) 1.59
Academic attainment and special educational needs in extremely preterm children at 11 years of age: the EPICure study. Arch Dis Child Fetal Neonatal Ed (2009) 1.55
Etiology of retrolental fibroplasia and preliminary report of cooperative study of retrolental fibroplasia. Trans Am Acad Ophthalmol Otolaryngol (1955) 1.52
Development of the primate retinal vasculature. Prog Retin Eye Res (2001) 1.51
New insights into the development of retinopathy of prematurity--importance of early weight gain. Acta Paediatr (2009) 1.49
Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes. Diabetes (1996) 1.49
Insulin-like growth factor-I is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2. J Neurosci (2001) 1.48
Learning disabilities in children with very low birthweight: prevalence, neuropsychological correlates, and educational interventions. J Learn Disabil (2005) 1.46
Spectral-domain optical coherence tomographic assessment of severity of cystoid macular edema in retinopathy of prematurity. Arch Ophthalmol (2012) 1.43
The neurovascular retina in retinopathy of prematurity. Prog Retin Eye Res (2009) 1.41
Growth of pulmonary microvasculature in ventilated preterm infants. Am J Respir Crit Care Med (2005) 1.39
Early school-based learning difficulties in children born very preterm. Early Hum Dev (2008) 1.36
Homozygous and heterozygous expression of a novel insulin-like growth factor-I mutation. J Clin Endocrinol Metab (2005) 1.35
Blood gases, pH, and lactate in appropriate- and small-for-gestational-age fetuses. Am J Obstet Gynecol (1989) 1.35
Transient IGF-I gene expression during the maturation of functionally related central projection neurons. J Neurosci (1991) 1.35
Pathogenesis of retinopathy of prematurity. Semin Neonatol (2003) 1.32
Neonatal white matter abnormalities an important predictor of neurocognitive outcome for very preterm children. PLoS One (2012) 1.30
Very preterm children show impairments across multiple neurodevelopmental domains by age 4 years. Arch Dis Child Fetal Neonatal Ed (2009) 1.28
Lipopolysaccharide-activated microglia induce death of oligodendrocyte progenitor cells and impede their development. Neuroscience (2009) 1.25
Oxygen-induced retinopathy in mice: amplification by neonatal IGF-I deficit and attenuation by IGF-I administration. Pediatr Res (2009) 1.20
In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: evidence that IGF-I increases proliferation of granule cell progenitors. Brain Res Dev Brain Res (1996) 1.20
Pathogenesis of retinopathy of prematurity. Acta Paediatr Suppl (2002) 1.20
Insulin-like growth factor I gene deletion causing intrauterine growth retardation and severe short stature. Acta Paediatr Suppl (1997) 1.19
Insulin-like growth factor-I stimulates both cell growth and lipogenesis during differentiation of human mesenchymal stem cells into adipocytes. J Clin Endocrinol Metab (2004) 1.18
The cone electroretinogram in retinopathy of prematurity. Invest Ophthalmol Vis Sci (2008) 1.17
Insulin-like growth factor-I is a differentiation factor for postmitotic CNS stem cell-derived neuronal precursors: distinct actions from those of brain-derived neurotrophic factor. J Neurosci (1998) 1.16
Prevalence of motor-skill impairment in preterm children who do not develop cerebral palsy: a systematic review. Dev Med Child Neurol (2010) 1.15
Natural history of retinopathy of prematurity in infants born before 27 weeks' gestation in Sweden. Arch Ophthalmol (2010) 1.15
Multifocal ERG in subjects with a history of retinopathy of prematurity. Doc Ophthalmol (2006) 1.14
Retinoschisis detected with handheld spectral-domain optical coherence tomography in neonates with advanced retinopathy of prematurity. Arch Ophthalmol (2010) 1.14
Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action. Diabetes (2006) 1.10
Insulin-like growth factor-I prevents apoptosis in neurons after nerve growth factor withdrawal. J Neurobiol (1998) 1.09
Subclinical macular findings in infants screened for retinopathy of prematurity with spectral-domain optical coherence tomography. Ophthalmology (2013) 1.07
Development of scotopic visual thresholds in retinopathy of prematurity. Invest Ophthalmol Vis Sci (2007) 1.07
Quantification and localization of the IGF/insulin system expression in retinal blood vessels and neurons during oxygen-induced retinopathy in mice. Invest Ophthalmol Vis Sci (2008) 1.06
A population-based study on the visual outcome in 10-year-old preterm and full-term children. Arch Ophthalmol (2005) 1.04
Type 1 insulin-like growth factor receptor signaling is essential for the development of the hippocampal formation and dentate gyrus. J Neurosci Res (2009) 1.03
Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats. Exp Neurol (2009) 1.02
Role of OCT in the diagnosis and follow up of diabetic macular edema. Semin Ophthalmol (2003) 1.01
Special care and school difficulties in 8-year-old very preterm children: the Epipage cohort study. PLoS One (2011) 1.00
Acute proliferative retrolental fibroplasia: multivariate risk analysis. Trans Am Ophthalmol Soc (1983) 1.00
A variable degree of intrauterine and postnatal growth retardation in a family with a missense mutation in the insulin-like growth factor I receptor. J Clin Endocrinol Metab (2006) 0.99
Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons. J Neurochem (2001) 0.99
Neurodevelopmental effects of insulin-like growth factor signaling. Front Neuroendocrinol (2012) 0.98
Central macular thickness is correlated with gestational age at birth in prematurely born children. Br J Ophthalmol (2010) 0.96
Retinal nerve fibre layer thickness in school-aged prematurely-born children compared to children born at term. Br J Ophthalmol (2012) 0.96
Postnatal decrease in circulating insulin-like growth factor-I and low brain volumes in very preterm infants. J Clin Endocrinol Metab (2011) 0.96
A pharmacokinetic and dosing study of intravenous insulin-like growth factor-I and IGF-binding protein-3 complex to preterm infants. Pediatr Res (2009) 0.95
Retinopathy of prematurity, a decrease in frequency and severity. Trends over 16 years in a Danish county. Acta Ophthalmol Scand (2000) 0.95
Increased expression of insulin-like growth factor-I (IGF-I) during embryonic development produces neocortical overgrowth with differentially greater effects on specific cytoarchitectonic areas and cortical layers. Brain Res Dev Brain Res (2004) 0.92
Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and development. Mol Endocrinol (2004) 0.91
Optical coherence tomography in retinopathy of prematurity: looking beyond the vessels. Clin Perinatol (2013) 0.90
Coordinate expression of insulin-like growth factor system components by neurons and neuroglia during retinal and cerebellar development. J Neurosci (1992) 0.90
Dark-adapted thresholds in children with histories of mild retinopathy of prematurity. Invest Ophthalmol Vis Sci (1997) 0.90
The role of spectral-domain OCT in the diagnosis and management of neovascular age-related macular degeneration. Ophthalmic Surg Lasers Imaging (2011) 0.90
Trophic effects of insulin-like growth factor-I on fetal rat hypothalamic cells in culture. Neuroscience (1990) 0.90
Ontogeny of insulin-like growth factor-binding protein-1, -2, and -3: quantitative measurements by radioimmunoassay in human fetal serum. Pediatr Res (1994) 0.90
Current role of cryotherapy in retinopathy of prematurity: a report by the American Academy of Ophthalmology. Ophthalmology (2012) 0.89
Serum growth hormone levels and the response of diabetic retinopathy to pituitary ablation. Br Med J (1969) 0.89
The biology of retinopathy of prematurity: how knowledge of pathogenesis guides treatment. Clin Perinatol (2013) 0.89
Poorer neurodevelopmental outcomes associated with cystoid macular edema identified in preterm infants in the intensive care nursery. Ophthalmology (2014) 0.89
Apoptotic cell death and caspase-3 activation induced by N-methyl-D-aspartate receptor antagonists and their prevention by insulin-like growth factor I. J Neurochem (1999) 0.87
The management of retinopathy of prematurity. Paediatr Drugs (2001) 0.87
IGF-1 can either protect against or increase LPS-induced damage in the developing rat brain. Pediatr Res (2010) 0.87
Heterozygous mutation within a kinase-conserved motif of the insulin-like growth factor I receptor causes intrauterine and postnatal growth retardation. J Clin Endocrinol Metab (2010) 0.86
Serum concentrations of vascular endothelial growth factor in relation to retinopathy of prematurity. Pediatr Res (2015) 0.80
Insulin-like growth factor 1 has multisystem effects on foetal and preterm infant development. Acta Paediatr (2016) 0.79
Retinopathy of prematurity: the need for prevention. Eye Brain (2016) 0.76
Photoreceptor glucose metabolism determines normal retinal vascular growth. EMBO Mol Med (2017) 0.75
Cerebellar Exposure to Cell-Free Hemoglobin Following Preterm Intraventricular Hemorrhage: Causal in Cerebellar Damage? Transl Stroke Res (2017) 0.75