Published in Immunol Cell Biol on November 08, 2016
Phenotypic analysis of antigen-specific T lymphocytes. Science (1996) 24.26
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science (2002) 19.77
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck. Cell (1988) 10.47
Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer (2008) 9.82
Adaptive immunity maintains occult cancer in an equilibrium state. Nature (2007) 8.14
Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J Immunother (2003) 5.59
A very high level of crossreactivity is an essential feature of the T-cell receptor. Immunol Today (1998) 5.07
T cell killing does not require the formation of a stable mature immunological synapse. Nat Immunol (2004) 3.85
Human tumor antigens recognized by T lymphocytes. J Exp Med (1996) 3.63
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. Immunity (2003) 3.04
Directed evolution of human T-cell receptors with picomolar affinities by phage display. Nat Biotechnol (2005) 2.97
Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood (2013) 2.91
The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex. Proc Natl Acad Sci U S A (1989) 2.80
Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus. J Exp Med (1994) 2.47
CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature (1995) 2.15
A single autoimmune T cell receptor recognizes more than a million different peptides. J Biol Chem (2011) 2.06
Transfection of the CD8 gene enhances T-cell recognition. Nature (1987) 2.05
Human TCR-binding affinity is governed by MHC class restriction. J Immunol (2007) 2.02
T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics. Immunity (1999) 1.98
The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities. J Biol Chem (2003) 1.92
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface. J Biol Chem (2005) 1.92
Tricks with tetramers: how to get the most from multimeric peptide-MHC. Immunology (2009) 1.78
T cell antigen receptor recognition of antigen-presenting molecules. Annu Rev Immunol (2014) 1.64
CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes. J Exp Med (2001) 1.61
The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain. J Biol Chem (2001) 1.59
Monoclonal TCR-redirected tumor cell killing. Nat Med (2012) 1.57
Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor. J Biol Chem (2009) 1.51
Essential role of CD8 palmitoylation in CD8 coreceptor function. J Immunol (2000) 1.46
Peptide-MHC class I tetrameric complexes display exquisite ligand specificity. J Immunol (2000) 1.41
Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands. Trends Immunol (2002) 1.40
CD8 kinetically promotes ligand binding to the T-cell antigen receptor. Biophys J (2005) 1.38
Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor. Immunol Today (2000) 1.32
Structural and biophysical determinants of αβ T-cell antigen recognition. Immunology (2012) 1.30
Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region. Eur J Immunol (2007) 1.24
CD4 and CD8: modulators of T-cell receptor recognition of antigen and of immune responses? Curr Opin Immunol (1998) 1.23
Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha. J Biol Chem (2000) 1.21
CD8 controls T cell cross-reactivity. J Immunol (2010) 1.15
Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection. Blood (2008) 1.07
The CD8 coreceptor revisited: one chain good, two chains better. Immunity (1994) 1.04
Immunotherapy with gene-modified T cells: limiting side effects provides new challenges. Gene Ther (2013) 1.01
Coreceptor CD8-driven modulation of T cell antigen receptor specificity. J Theor Biol (2007) 1.00
The molecular determinants of CD8 co-receptor function. Immunology (2012) 0.94
MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. J Immunol (2010) 0.92
Prospects for immunotherapy of malignant disease. Clin Exp Immunol (2003) 0.85
Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding. J Immunol (2006) 0.83
Individual MHCI-Restricted T-Cell Receptors are Characterized by a Unique Peptide Recognition Signature. Front Immunol (2013) 0.78